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Original Article | Open Access

The influence of different kVs and phantoms on computed tomography number to relative electron density calibration curve for radiotherapy dose calculation

Ahmed Mousa Jaafar1,2, Hussein Elsayed3, Magdy M. Khalil1,4, Mohamed Nabil Yaseen1, Ahmed Alshewered5 ( ), Hany Ammar3,6
Faculty of Science, Department of Physics, Helwan University, Helwan, Egypt
Baghdad Center for Radiotherapy and Nuclear Medicine, Medical City, Iraq
Radiation Oncology Department, Children's Cancer Hospital, Cairo, Egypt
Department of Biotechnology, School of Biotechnology, Badr University in Cairo (BUC), Cairo, Egypt
Misan RO Center, Misan Health Directorate, Ministry of Health and Environment, Misan, Iraq
Faculty of Medicine, Clinical Oncology Department, Aswan University, Aswan, Egypt
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Abstract

Objective

This study was carried out to analyze the effect of varying kilovoltage peak (kVp) on Hounsfield unit (HU) for various tissue substitutes in two different phantoms and their dosimetric impact on dose calculation in Monaco treatment planning system version 5.11.02.

Methods

HU for different density materials was obtained from computed tomography images of the phantoms acquired at various kVps (80, 100, and 120). Two different phantoms (CatPhan 503 and CIRS 062 M) were used to construct their suitability for computed tomography. Both scan phantoms were used to perform 30 volumetric modulated arc therapy plans.

Results

No significant variation in the CatPhan phantom was observed for HU of different density materials with various kVp. In contrast, a direct relationship between kVp and HU was observed in the case of CIRS phantom, as increases in the kVp resulted in a corresponding decrease in HU. The maximum HU deviation was found in breast tissue. HU is inversely proportional to the kVp for tissues. There was a difference of ≥22% in HU values between the highest densities in CatPhan and CIRS phantoms.

Conclusion

CIRS 062 M was found more convenient for calibration than CatPhan 503, especially for high-density material.

Keywords

computed tomographyelectron density calibration curveHounsfield unitphantomsvolumetric modulated arc therapy

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Precision Radiation Oncology
Volume 6 Issue 4,
December 2022
Pages 289-297
DOI: 10.1002/pro6.1177
Cite this article:
Jaafar AM, Elsayed H, Khalil MM, et al. The influence of different kVs and phantoms on computed tomography number to relative electron density calibration curve for radiotherapy dose calculation. Precision Radiation Oncology, 2022, 6(4): 289-297. https://doi.org/10.1002/pro6.1177

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Received: 30 June 2022
Revised: 24 October 2022
Accepted: 31 October 2022
Published: 26 November 2022
© 2022 The Authors. Precision Radiation Oncology published by John Wiley & Sons Australia, Ltd on behalf of Shandong Cancer Hospital & Institute.

This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
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