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Research Article

Highly stable organic fluorescent nanorods for living-cell imaging

Minhuan Lan1,§Jinfeng Zhang1,§Xiaoyue Zhu1Pengfei Wang2( )Xianfeng Chen1( )Chun-Sing Lee1Wenjun Zhang1( )
Center of Super-Diamond and Advanced Films (COSDAF)Department of Physics and Materials ScienceCity University of Hong Kong, Hong Kong SARChina
Key Laboratory of Photochemical Conversion and Optoelectronic MaterialsTechnical Institute of Physics and Chemistry (TIPC)Chinese Academy of Sciences (CAS)Beijing100190China

§ These authors contributed equally to this work

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Abstract

Metal-free, organic-dye-based fluorescent nanorods were fabricated through a simple solvent-exchange procedure. The as-prepared nanorods exhibit low toxicity to living cells and excellent photostability. Furthermore, they are stable in solutions of various pHs and high ionic strength and in solutions with interfering metal ions. Compared with the free DPP-Br molecules in THF, these nanorods exhibit larger Stokes shift, broader absorption spectra, and greatly improved photostability. We successfully demonstrated the application of the nanorods, including their aforementioned beneficial characteristics, as a good fluorescence probe for bio-imaging.

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Nano Research
Pages 2380-2389
Cite this article:
Lan M, Zhang J, Zhu X, et al. Highly stable organic fluorescent nanorods for living-cell imaging. Nano Research, 2015, 8(7): 2380-2389. https://doi.org/10.1007/s12274-015-0748-4

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Received: 05 September 2014
Revised: 24 December 2014
Accepted: 13 February 2015
Published: 24 April 2015
© Tsinghua University Press and Springer-Verlag Berlin Heidelberg 2014
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