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Review Article

A prospective future towards bio/medical technology and bioelectronics based on 2D vdWs heterostructures

Guru Prakash Neupane1,§( ), Linglong Zhang1,§, Tanju Yildirim1, Kai Zhou2, Bowen Wang1, Yilin Tang1, Wendi Ma1, Yunzhou Xue3( ), Yuerui Lu1( )
Research School of Electrical, Energy and Materials Engineering, College of Engineering and Computer Science, The Australian National University, Canberra ACT 2601, Australia
College of Mechatronics and Control Engineering, Shenzhen University, Nan-hai Ave 3688, Shenzhen 518060, China
College of Chemistry and Environmental Engineering, Shenzhen University, Shenzhen 518052, China

§ Guru Prakash Neupane and Linglong Zhang contributed equally to this work.

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Graphical Abstract

Abstract

Nano-biotechnology research has become extremely important due to the possibilities in manipulation and characterization of biological molecules through nanodevices. Nanomaterials exhibit exciting electrical, optoelectronic, magnetic, mechanical and chemical properties that can be exploited to develop efficient biosensors or bio-probes. Those unique properties in nanomaterials can also be used in bioimaging and cancer therapeutics, where biomolecules influence the inherent properties in nanomaterials. Effective manipulation of nanomaterial properties can lead to many breakthroughs in nanotechnology applications. Nowadays, two-dimensional (2D) nanomaterials have emerged as viable materials for nanotechnology. Large cross-section area and functional availability of 2D or one-dimensional (1D) quantum limit in these nanomaterials allow greater flexibility and better nanodevice performance. 2D nanomaterials enable advanced bioelectronics to be more easily integrated due to their atomic thickness, biocompatibility, mechanical flexibility and conformity. Furthermore, with the development of 2D material heterostructures, enhanced material properties can be obtained which can directly influence bio-nanotechnology applications. This article firstly reviews the development of various types of 2D heterostructures in a wide variety of nano-biotechnology applications. Furthermore, future 2D heterostructure scopes in bioimaging, nanomedicine, bio-markers/therapy and bioelectronics are discussed. This paper can be an avenue for providing a wide scope for 2D van der Waals (vdWs) heterostructures in bio- and medical fields.

Keywords

two-dimensional (2D) nanomaterials heterostructuresbioimagingnano-medicinenano-bio-electronicswearable 2D nanotechnology

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Nano Research
Volume 13 Issue 1,
January 2020
Pages 1-17
DOI: 10.1007/s12274-019-2585-3
Cite this article:
Neupane GP, Zhang L, Yildirim T, et al. A prospective future towards bio/medical technology and bioelectronics based on 2D vdWs heterostructures. Nano Research, 2020, 13(1): 1-17. https://doi.org/10.1007/s12274-019-2585-3
Topics:
BiocompatibilityBiomolecules BiotechnologyMedical nanotechnologyVan der Waals forces

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Received: 08 October 2019
Revised: 21 November 2019
Accepted: 27 November 2019
Published: 19 December 2019
© Tsinghua University Press and Springer-Verlag GmbH Germany, part of Springer Nature 2019
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