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Research Article

Single-walled carbon nanotube based SERS substrate with single molecule sensitivity

Chenmaya Xia, Daqi Zhang, Henan Li, Sheng Li, Haoming Liu, Li Ding, Xiyan Liu, Min Lyu, Ruoming Li, Juan Yang( ), Yan Li( )
Beijing National Laboratory for Molecular Sciences Key Laboratory for the Physics and Chemistry of Nanodevices State Key Laboratory of Rare Earth Materials Chemistry and Applications College of Chemistry and Molecular Engineering Peking UniversityBeijing 100871 China
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Abstract

In single molecule study, surface-enhanced Raman scattering (SERS) has the advantage of specifically providing structural information of the molecules targeted. The main challenge in single molecule SERS is developing reusable plasmonic substrates that ensures single molecule sensitivity and acquires intrinsic information of molecules. Here, we proposed a strategy to utilize single- walled carbon nanotubes (SWNTs) to construct SERS substrates. Employing ultrasonic spray pyrolysis, we prepared in situ polyhedral gold nanocrystals closely spaced and attached to nanotubes, ensuring valid hot spots formed along the tube-walls. With such SERS substrates, we proved the single molecule detection by the statistical analysis based on the natural abundance of isotopes. Since SWNTs provide non-chemical bonding adsorption sites, our SERS substrates are easily reusable and have a unique advantage of preserving the intrinsic property of the molecules detected. Using SWNTs to build SERS substrates may become a powerful general strategy in various static and dynamic studies of single molecules.

Keywords

goldsingle-walled carbon nanotubessurface-enhanced Raman scatteringsingle molecule studies

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Nano Research
Volume 15 Issue 1,
January 2022
Pages 694-700
DOI: 10.1007/s12274-021-3549-y
Cite this article:
Xia C, Zhang D, Li H, et al. Single-walled carbon nanotube based SERS substrate with single molecule sensitivity. Nano Research, 2022, 15(1): 694-700. https://doi.org/10.1007/s12274-021-3549-y
Topics:
Single walled carbon nanotubes (SWCN)

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Received: 05 March 2021
Revised: 24 April 2021
Accepted: 27 April 2021
Published: 10 September 2021
© Tsinghua University Press and Springer-Verlag GmbH Germany, part of Springer Nature 2021
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