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Research Article

Multifunctional N,S-doped and methionine functionalized carbon dots for on−off−on Fe3+ and ascorbic acid sensing, cell imaging, and fluorescent ink applying

Zheng Yang1,2,3, Tiantian Xu2, Shaobing Zhang2, Hui Li1,2, Yali Ji1, Xiaodan Jia2,3, Jianli Li1( )
Key Laboratory of Synthetic and Natural Functional Molecule of the Ministry of Education, College of Chemistry & Materials Science, Northwest University, Xi’an 710127, China
College of Chemistry and Chemical Engineering, Xi’an University of Science and Technology, Xi’an 710054, China
Key Laboratory of Coal Resources Exploration and Comprehensive Utilization, Ministry of Land and Resources, Xi’an 710012, China
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Graphical Abstract

This work presents multifunctional N,S-doped methionine functionalized carbon dots as promising fluorescent sensors, ink, and message encryption materials in solution, filter paper, and hydrogels for on–off–on sensitive and selective response, absorbing, and cell imaging of Fe3+ and ascorbic acid.

Abstract

Fluorescent carbon dots (CDs) have been identified as potential nanosensors and attracted tremendous research interests in wide areas including anti-counterfeiting, environmental and biological sensing and imaging in considering of the attractive optical properties. In this work, we present a CDs based fluorescent sensor from polyvinylpyrrolidone, citric acid, and methionine as precursors by hydrothermal approach. The selective quantifying of Fe3+ and ascorbic acid (AA) are based on the fluorescent on–off–on process, in which the fluorescent quenching is induced by the coordination of the Fe3+ on the surface of the CDs, while the fluorescence recovery is mainly attributed to redox reaction between Fe3+ and AA, breaking the coordination and bringing the fluorescence back. Inspired by the good water solubility and biocompatibility, significant photostability, superior photobleaching resistance as well as high selectivity, sensitivity, and interference immunity, which are constructed mainly from the N,S-doping and methionine surface functionalization, the CDs have not only been employed as fluorescence ink in multiple anti-counterfeiting printing and confidential document writing or transmitting, but also been developed as promising fluorescence sensors in solution and solid by CDs doped test strips and hydrogels for effectively monitoring and removing of Fe3+ and AA in environmental aqueous solution. The CDs have been also implemented as effective diagnostic candidates for imaging and tracking of Fe3+ and AA in living cells, accelerating the understanding of their function and importance in related biological processes for the prevention and treatment specific diseases.

Keywords

carbon dotsfluorescent sensorsFe3+ascorbic acidfluorescent inkmessage encryption

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Nano Research
Volume 16 Issue 4,
April 2023
Pages 5401-5411
DOI: 10.1007/s12274-022-5107-7
Cite this article:
Yang Z, Xu T, Zhang S, et al. Multifunctional N,S-doped and methionine functionalized carbon dots for on−off−on Fe3+ and ascorbic acid sensing, cell imaging, and fluorescent ink applying. Nano Research, 2023, 16(4): 5401-5411. https://doi.org/10.1007/s12274-022-5107-7
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Received: 08 August 2022
Revised: 19 September 2022
Accepted: 26 September 2022
Published: 09 November 2022
© Tsinghua University Press 2022
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