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Research Article

Low-temperature optothermal nanotweezers

Jianxing Zhou1, Xiaoqi Dai1, Yuhang Peng1, Yili Zhong1, Ho-Pui Ho2, Yonghong Shao1, Bruce Zhi Gao3, Junle Qu1, Jiajie Chen1()
State Key Laboratory of Radio Frequency Heterogeneous Integration; Key Laboratory of Optoelectronic Devices and Systems of Ministry of Education and Guangdong Province, College of Physics and Optoelectronics Engineering, Shenzhen University, Shenzhen 518060, China
Department of Biomedical Engineering, The Chinese University of Hong Kong, Hong Kong 999077, China
Department of Bioengineering and COMSET, Clemson University, Clemson, SC 29634, USA
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We developed low-temperature optothermal nanotweezers by incorporating a self-made microfluidic refrigerator. It is free from auxiliary surfactants or semiconductor materials and works at low temperature (0–4 °C) to avoid possible optothermal influence.

Abstract

Optical tweezers that rely on laser irradiation to capture and manipulate nanoparticles have provided powerful tools for biological and biochemistry studies. However, the existence of optical diffraction-limit and the thermal damage caused by high laser power hinder the wider application of optical tweezers in the biological field. For the past decade, the emergence of optothermal tweezers has solved the above problems to a certain extent, while the auxiliary agents used in optothermal tweezers still limit their biocompatibility. Here, we report a kind of nanotweezers based on the sign transformation of the thermophoresis coefficient of colloidal particles in low-temperature environment. Using a self-made microfluidic refrigerator to reduce the ambient temperature to around 0 °C in the microfluidic cell, we can control a single nanoparticle at lower laser power without adding additional agent solute in the solution. This novel optical tweezering scheme has provided a new path for the manipulation of inorganic nanoparticles as well as biological particles.

Keywords

optothermal tweezersoptical manipulationmicrofluidic devicethermophoresisthermo-osmotic flow

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Nano Research
Volume 16 Issue 5,
May 2023
Pages 7710-7715
DOI: 10.1007/s12274-023-5659-1
Cite this article:
Zhou J, Dai X, Peng Y, et al. Low-temperature optothermal nanotweezers. Nano Research, 2023, 16(5): 7710-7715. https://doi.org/10.1007/s12274-023-5659-1
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