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Research Article

Peroxidase-like active Cu-ZIF-8 with rich copper(I)-nitrogen sites for excellent antibacterial performances toward drug-resistant bacteria

Xiaoze Wang1,2, Hui Wang3, Jingkun Zhang1,2, Ning Han1,2, Wenjun Ma1,2, Donghai Zhang1,2, Mingshui Yao1,2( ), Xianliang Wang4( ), Yunfa Chen1,2( )
State Key Laboratory of Mesoscience and Engineering, Institute of Process Engineering, Chinese Academy of Sciences, Beijing 100190, China
University of the Chinese Academy of Sciences, Beijing 100049, China
Laboratory of Theoretical and Computational Nanoscience, CAS Key Laboratory of Nanosystem and Hierarchial Fabrication, CAS Center for Excellence in Nanoscience, National Center for Nanoscience and Technology, Beijing 100190, China
China CDC Key Laboratory of Environment and Population Health, National Institute of Environmental Health, Chinese Center for Disease Control and Prevention, Beijing 100021, China
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Graphical Abstract

The abundant Cu-Nx active sites enable copper-doped ZIF-8 to possess efficient peroxidase-like activity and excellent antibacterial properties.

Abstract

Bacterial pathogens pose a serious threat to human health, and there is an urgent need to develop highly effective antibacterial materials to eliminate the increasingly serious contamination of drug-resistant bacteria. Here, a Cu-doped ZIF-8 particle with unsaturated copper exhibits high peroxidase-like activity. 99.998% antibacterial efficiency against S. aureus can be achieved for 30 min at a low concentration of 50 μg·mL−1, as well as complete sterilization against E. coli (up to 8 log). 99.999% antibacterial efficiency against Methicillin-resistant Staphylococcus aureus can be achieved, performing orders of magnitude higher than Vancomycin. The mechanism shows that the unsaturated Cu-Nx sites are enzyme-like active centers, which could promote the consumption of bacteria reducing substances by H2O2, and the generated *OH further aggravates bacterial oxidative stress and membrane damage. More importantly, the oxidation activity of adsorbed oxygen species on Cu-ZIF-8 is enhanced by charge transfer and structural changes between the ligand and copper center like natural enzymes. Cu-doped ZIF-8 with peroxidase-like activity shows great potential in antibacterial application and the revealed catalytic mechanism is helpful for understanding the high antibacterial activity of nanoparticles with Cu-Nx sites.

Keywords

Cu-doped ZIF-8peroxidase-likereactive oxygen species (ROS)catalytic mechanismantibacterial activity

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References

[1]

Jones, K. E.; Patel, N. G.; Levy, M. A.; Storeygard, A.; Balk, D.; Gittleman, J. L.; Daszak, P. Global trends in emerging infectious diseases. Nature 2008, 451, 990–993.
Crossref Google Scholar
[2]

Ikuta, K. S.; Swetschinski, L. R.; Robles Aguilar, G.; Sharara, F.; Mestrovic, T.; Gray, A. P.; Davis Weaver, N.; Wool, E. E.; Han, C.; Gershberg Hayoon, A. et al. Global mortality associated with 33 bacterial pathogens in 2019: A systematic analysis for the Global Burden of Disease Study 2019. Lancet 2022, 400, 2221–2248.
Crossref Google Scholar
[3]

Zhang, Y.; Wen, W. H.; Pu, J. Y.; Tang, M. C.; Zhang, L. W.; Peng, C.; Xu, Y. Q.; Tang, G. L. Extracellularly oxidative activation and inactivation of matured prodrug for cryptic self-resistance in naphthyridinomycin biosynthesis. Proc. Natl. Acad. Sci. USA 2018, 115, 11232–11237.
Crossref Google Scholar
[4]

Cao, M. Y.; Chang, Z. S.; Tan, J. S.; Wang, X. N.; Zhang, P. F.; Lin, S.; Liu, J. Q.; Li, A. H. Superoxide radical-mediated self-synthesized Au/MoO3- x hybrids with enhanced peroxidase-like activity and photothermal effect for anti-MRSA therapy. ACS Appl. Mater. Interfaces 2022, 14, 13025–13037.
Crossref Google Scholar
[5]

Wang, H.; Sarwar, M. T.; Tian, L. Y.; Bao, W. X.; Yang, H. M. Nanoclay modulates cation occupancy in manganese ferrite for catalytic antibacterial treatment. Inorg. Chem. 2022, 61, 17692–17702.
Crossref Google Scholar
[6]

Li, L.; Cao, S. J.; Wu, Z. H.; Guo, R. Q.; Xie, L.; Wang, L. Y.; Tang, Y. J.; Li, Q.; Luo, X. L.; Ma, L. et al. Modulating electron transfer in vanadium-based artificial enzymes for enhanced ROS-catalysis and disinfection. Adv. Mater. 2022, 34, 2108646.
Crossref Google Scholar
[7]

Ali, S. R.; De, M. Thiolated ligand-functionalized MoS2 nanosheets for peroxidase-like activities. ACS Appl. Nano Mater. 2021, 4, 12682–12689.
Crossref Google Scholar
[8]

Yin, W. Y.; Yu, J.; Lv, F. T.; Yan, L.; Zheng, L. R.; Gu, Z. J.; Zhao, Y. L. Functionalized nano-MoS2 with peroxidase catalytic and near-infrared photothermal activities for safe and synergetic wound antibacterial applications. ACS Nano 2016, 10, 11000–11011.
Crossref Google Scholar
[9]

Han, D. L.; Han, Y. J.; Li, J.; Liu, X. M.; Yeung, K. W. K.; Zheng, Y. F.; Cui, Z. D.; Yang, X. J.; Liang, Y. Q.; Li, Z. Y. et al. Enhanced photocatalytic activity and photothermal effects of cu-doped metal-organic frameworks for rapid treatment of bacteria-infected wounds. Appl. Catal. B: Environ. 2020, 261, 118248.
Crossref Google Scholar
[10]

Zhang, R. M.; Song, C. J.; Kou, M. P.; Yin, P. Q.; Jin, X. L.; Wang, L.; Deng, Y.; Wang, B.; Xia, D. H.; Wong, P. K. et al. Sterilization of Escherichia coli by photothermal synergy of WO3- x /C nanosheet under infrared light irradiation. Environ. Sci. Technol. 2020, 54, 3691–3701.
Crossref Google Scholar
[11]

Li, P.; Li, J. Z.; Feng, X.; Li, J.; Hao, Y. C.; Zhang, J. W.; Wang, H.; Yin, A. X.; Zhou, J. W.; Ma, X. J. et al. Metal-organic frameworks with photocatalytic bactericidal activity for integrated air cleaning. Nat. Commun. 2019, 10, 2177.
Crossref Google Scholar
[12]

Liang, Z. D.; Wang, H. Q.; Zhang, K. N.; Ma, G.; Zhu, L. S.; Zhou, L.; Yan, B. Oxygen-defective MnO2/ZIF-8 nanorods with enhanced antibacterial activity under solar light. Chem. Eng. J. 2022, 428, 131349.
Crossref Google Scholar
[13]

Dong, F. L.; Pang, Z.; Yang, S. Y.; Lin, Q. F.; Song, S.; Li, C.; Ma, X. Y.; Nie, S. X. Improving wastewater treatment by triboelectric-photo/electric coupling effect. ACS Nano 2022, 16, 3449–3475.
Crossref Google Scholar
[14]

Wang, W. W.; Pan, X. T.; Yang, H. L.; Wang, H.; Wu, Q. Y.; Zheng, L. R.; Xu, B. L.; Wang, J. H.; Shi, X. H.; Bai, F. et al. Bioactive metal-organic frameworks with specific metal-nitrogen (M-N) active sites for efficient sonodynamic tumor therapy. ACS Nano 2021, 15, 20003–20012.
Crossref Google Scholar
[15]

Liang, M. M.; Yan, X. Y. Nanozymes: From new concepts, mechanisms, and standards to applications. Acc. Chem. Res. 2019, 52, 2190–2200.
Crossref Google Scholar
[16]

Ji, S. F.; Jiang, B.; Hao, H. G.; Chen, Y. J.; Dong, J. C.; Mao, Y.; Zhang, Z. D.; Gao, R.; Chen, W. X.; Zhang, R. F. et al. Matching the kinetics of natural enzymes with a single-atom iron nanozyme. Nat. Catal. 2021, 4, 407–417.
Crossref Google Scholar
[17]

Xing, Y. X.; Wang, L.; Wang, L. C.; Huang, J. X.; Wang, S.; Xie, X. Y.; Zhu, J.; Ding, T.; Cai, K. Y.; Zhang, J. X. Flower-like nanozymes with large accessibility of single atom catalysis sites for ROS generation boosted tumor therapy. Adv. Funct. Mater. 2022, 32, 2111171.
Crossref Google Scholar
[18]

Ai, Y. J.; Hu, Z. N.; Liang, X. P.; Sun, H. B.; Xin, H. B.; Liang, Q. L. Recent advances in nanozymes: From matters to bioapplications. Adv. Funct. Mater. 2022, 32, 2110432.
Crossref Google Scholar
[19]

Yao, M. S.; Otake, K. I.; Zheng, J. J.; Tsujimoto, M.; Gu, Y. F.; Zheng, L.; Wang, P.; Mohana, S.; Bonneau, M.; Koganezawa, T. et al. Integrated soft porosity and electrical properties of conductive-on-insulating metal-organic framework nanocrystals. Angew. Chem., Int. Ed. 2023, 62, e202303903.
Crossref Google Scholar
[20]

Gao, L. Z.; Zhuang, J.; Nie, L.; Zhang, J. B.; Zhang, Y.; Gu, N.; Wang, T. H.; Feng, J.; Yang, D. L.; Perrett, S. et al. Intrinsic peroxidase-like activity of ferromagnetic nanoparticles. Nat. Nanotechnol. 2007, 2, 577–583.
Crossref Google Scholar
[21]

Natalio, F.; André, R.; Hartog, A. F.; Stoll, B.; Jochum, K. P.; Wever, R.; Tremel, W. Vanadium pentoxide nanoparticles mimic vanadium haloperoxidases and thwart biofilm formation. Nat. Nanotechnol. 2012, 7, 530–535.
Crossref Google Scholar
[22]

Huang, H. J.; Geng, W.; Wu, X. Z.; Zhang, Y. Y.; Xie, L.; Ma, T.; Cheng, C. Spiky artificial peroxidases with V-O-Fe pair sites for combating antibiotic-resistant pathogens. Angew. Chem., Int. Ed. 2024, 63, e202310811.
Crossref Google Scholar
[23]

Shan, J. Y.; Li, X.; Yang, K. L.; Xiu, W.; Wen, Q. R.; Zhang, Y. Q.; Yuwen, L. H.; Weng, L. X.; Teng, Z. G.; Wang, L. H. Efficient bacteria killing by Cu2WS4 nanocrystals with enzyme-like properties and bacteria-binding ability. ACS Nano 2019, 13, 13797–13808.
Crossref Google Scholar
[24]

Chen, Y. L.; Chen, F. M.; He, X. H.; Guo, C. Y.; Cheng, C. X.; Wu, Z. P.; He, Y.; Zhang, W. S.; Cui, F.; Wang, Y. S. et al. Myeloperoxidase-mimetic nanozyme generates hypochlorous acid for phagosomal bacteria elimination. Nano Today 2024, 54, 102137.
Crossref Google Scholar
[25]
Shi, X. D.; Lv, J.; Deng, S. L.; Zhou, F.; Mei, J. G.; Zheng, L.; Zhang, J. Construction of interlayer coupling diatomic nanozyme with peroxidase-like and photothermal activities for efficient synergistic antibacteria. Adv. Sci., in press, DOI: 10.1002/ADVS.202305823.
[26]
Zhang, C. Y.; Nan, Z. D. 2D/3D-shaped Fe0.8Ni0.2S2/ZIF-67 as a nanozyme for rapid measurement of H2O2 and ascorbic acid with a low limit of detection. Inorg. Chem. 2022 , 61, 13933–13943.
[27]

Hu, M. Z.; Yang, W. J.; Tan, H. Y.; Jin, L.; Zhang, L.; Kerns, P.; Dang, Y. L.; Dissanayake, S.; Schaefer, S.; Liu, B. et al. Template-free synthesis of mesoporous and crystalline transition metal oxide nanoplates with abundant surface defects. Matter 2020, 2, 1244–1259.
Crossref Google Scholar
[28]

Xie, Z. X.; Liang, S.; Cai, X. C.; Ding, B. B.; Huang, S. S.; Hou, Z. Y.; Ma, P. A.; Cheng, Z. Y.; Lin, J. O2-Cu/ZIF-8@Ce6/ZIF-8@F127 composite as a tumor microenvironment-responsive nanoplatform with enhanced photo-/chemodynamic antitumor efficacy. ACS Appl. Mater. Interfaces 2019, 11, 31671–31680.
Crossref Google Scholar
[29]

Kumari, G.; Jayaramulu, K.; Maji, T. K.; Narayana, C. Temperature induced structural transformations and gas adsorption in the zeolitic imidazolate framework ZIF-8: A Raman study. J. Phys. Chem. A 2013, 117, 11006–11012.
Crossref Google Scholar
[30]

Thomas, A.; Prakash, M. The role of binary mixtures of ionic liquids in ZIF-8 for selective gas storage and separation: A perspective from computational approaches. J. Phys. Chem. C 2020, 124, 26203–26213.
Crossref Google Scholar
[31]

Yang, Q. H.; Yang, C. C.; Lin, C. H.; Jiang, H. L. Metal-organic-framework-derived hollow N-doped porous carbon with ultrahigh concentrations of single Zn atoms for efficient carbon dioxide conversion. Angew. Chem., Int. Ed. 2019, 58, 3511–3515.
Crossref Google Scholar
[32]

Xu, B. L.; Wang, H.; Wang, W. W.; Gao, L. Z.; Li, S. S.; Pan, X. T.; Wang, H. Y.; Yang, H. L.; Meng, X. Q.; Wu, Q. W. et al. A single-atom nanozyme for wound disinfection applications. Angew. Chem., Int. Ed. 2019, 58, 4911–4916.
Crossref Google Scholar
[33]

Liang, N.; Ge, X. Y.; Zhao, Y.; Xia, L.; Song, Z. L.; Kong, R. M.; Qu, F. L. Promoting sensitive colorimetric detection of hydroquinone and Hg2+ via ZIF-8 dispersion enhanced oxidase-mimicking activity of MnO2 nanozyme. J. Hazard. Mater. 2023, 454, 131455.
Crossref Google Scholar
[34]

Park, K. S.; Ni, Z.; Côté, A. P.; Choi, J. Y.; Huang, R. D.; Uribe-Romo, F. J.; Chae, H. K.; O’Keeffe, M.; Yaghi, O. M. Exceptional chemical and thermal stability of zeolitic imidazolate frameworks. Proc. Natl. Acad. Sci. USA 2006, 103, 10186–10191.
Crossref Google Scholar
[35]

Taheri, M.; Bernardo, I. D.; Lowe, A.; Nisbet, D. R.; Tsuzuki, T. Green full conversion of ZnO nanopowders to well-dispersed zeolitic imidazolate framework-8 (ZIF-8) nanopowders via a stoichiometric mechanochemical reaction for fast dye adsorption. Cryst. Growth Des. 2020, 20, 2761–2773.
Crossref Google Scholar
[36]

Chen, C. L.; Alalouni, M. R.; Dong, X. L.; Cao, Z.; Cheng, Q. P.; Zheng, L. R.; Meng, L. K.; Guan, C.; Liu, L. M.; Abou-Hamad, E. et al. Highly active heterogeneous catalyst for ethylene dimerization prepared by selectively doping Ni on the surface of a zeolitic imidazolate framework. J. Am. Chem. Soc. 2021, 143, 7144–7153.
Crossref Google Scholar
[37]

Wang, X. Z.; Wang, H.; Cheng, J. F.; Li, H.; Wu, X. F.; Zhang, D. H.; Shi, X. H.; Zhang, J. K.; Han, N.; Chen, Y. F. Initiative ROS generation of Cu-doped ZIF-8 for excellent antibacterial performance. Chem. Eng. J. 2023, 466, 143201.
Crossref Google Scholar
[38]

Liu, Q.; Wan, K. W.; Shang, Y. X.; Wang, Z. G.; Zhang, Y. Y.; Dai, L. R.; Wang, C.; Wang, H.; Shi, X. H.; Liu, D. S. et al. Cofactor-free oxidase-mimetic nanomaterials from self-assembled histidine-rich peptides. Nat. Mater. 2021, 20, 395–402.
Crossref Google Scholar
[39]

Chen, Y.; Zou, H.; Yan, B.; Wu, X. J.; Cao, W. W.; Qian, Y. H.; Zheng, L.; Yang, G. W. Atomically dispersed Cu nanozyme with intensive ascorbate peroxidase mimic activity capable of alleviating ROS-mediated oxidation damage. Adv. Sci. 2022, 9, 2103977.
Crossref Google Scholar
[40]

Wang, Y. F.; Wang, M. K.; Wang, X. X.; Ma, W. Y.; Liu, J. X.; Li, J. Y. Designed synthesis of CD@Cu-ZIF-8 composites as excellent peroxidase mimics for assaying glutathione. Mater. Chem. Front. 2021, 5, 6125–6132.
Crossref Google Scholar
[41]

Nosaka, Y.; Nosaka, A. Y. Generation and detection of reactive oxygen species in photocatalysis. Chem. Rev. 2017, 117, 11302–11336.
Crossref Google Scholar
[42]

Liu, S. B.; Zeng, T. H.; Hofmann, M.; Burcombe, E.; Wei, J.; Jiang, R. R.; Kong, J.; Chen, Y. Antibacterial activity of graphite, graphite oxide, graphene oxide, and reduced graphene oxide: Membrane and oxidative stress. ACS Nano 2011, 5, 6971–6980.
Crossref Google Scholar
[43]

Cao, F. F.; Zhang, L.; Wang, H.; You, Y. W.; Wang, Y.; Gao, N.; Ren, J. S.; Qu, X. G. Defect-rich adhesive nanozymes as efficient antibiotics for enhanced bacterial inhibition. Angew. Chem., Int. Ed. 2019, 58, 16236–16242.
Crossref Google Scholar
[44]

Wan, Y.; Fang, J.; Wang, Y.; Sun, J.; Sun, Y.; Sun, X. L.; Qi, M. L.; Li, W.; Li, C. Y.; Zhou, Y. M. et al. Antibacterial zeolite imidazole frameworks with manganese doping for immunomodulation to accelerate infected wound healing. Adv. Healthcare Mater. 2021, 10, 2101515.
Crossref Google Scholar
[45]

Nagarjun, N.; Dhakshinamoorthy, A. A Cu-Doped ZIF-8 metal organic framework as a heterogeneous solid catalyst for aerobic oxidation of benzylic hydrocarbons. New J. Chem. 2019, 43, 18702–18712.
Crossref Google Scholar
[46]

Wang, Y. F.; Liu, X. S. B. J.; Wang, M. K.; Wang, X. X.; Ma, W. Y.; Li, J. Y. Facile synthesis of CDs@ZIF-8 nanocomposites as excellent peroxidase mimics for colorimetric detection of H2O2 and glutathione. Sens. Actuators B: Chem. 2021, 329, 129115.
Crossref Google Scholar
[47]

Dai, Y.; Xing, P.; Cui, X. Q.; Li, Z. H.; Zhang, X. M. Coexistence of Cu(II) and Cu(I) in Cu ion-doped zeolitic imidazolate frameworks (ZIF-8) for the dehydrogenative coupling of silanes with alcohols. Dalton Trans. 2019, 48, 16562–16568.
Crossref Google Scholar
[48]

Zhe, Y.; Wang, J. L.; Zhao, Z. Q.; Ren, G. Y.; Du, J. J.; Li, K.; Lin, Y. Q. Ascorbate oxidase-like nanozyme with high specificity for inhibition of cancer cell proliferation and online electrochemical DOPAC monitoring. Biosens. Bioelectron. 2023, 220, 114893.
Crossref Google Scholar
[49]

Zhang, C. H.; Liu, W. D.; Li, Z.; Yan, B. S.; Lin, J. T.; Chen, C. X.; Zhang, L. B.; Lu, Y. Z. Accelerated mimetic oxidase activity of polydopamine-dressed PdCu nanozyme for the detection of ascorbic acid related bioenzymes. ACS Sustain. Chem. Eng. 2022, 10, 1653–1663.
Crossref Google Scholar
[50]

Wang, T. Q.; Wang, Y. F.; Sun, M. Z.; Hanif, A.; Wu, H.; Gu, Q. F.; Ok, Y. S.; Tsang, D. C. W.; Li, J. Y.; Yu, J. H. et al. Thermally treated zeolitic imidazolate framework-8 (ZIF-8) for visible light photocatalytic degradation of gaseous formaldehyde. Chem. Sci. 2020, 11, 6670–6681.
Crossref Google Scholar
[51]

Liu, F. D.; He, H.; Zhang, C. B.; Feng, Z. C.; Zheng, L. R.; Xie, Y. N.; Hu, T. D. Selective catalytic reduction of NO with NH3 over iron titanate catalyst: Catalytic performance and characterization. Appl. Catal. B: Environ. 2010, 96, 408–420.
Crossref Google Scholar
[52]

Ju, Q. Y.; Zheng, J. J.; Xu, L.; Jiang, H. Y.; Xue, Z. Q.; Bai, L.; Guo, Y. Y.; Yao, M. S.; Zhu, T. Y. Enhanced carbon capture with motif-rich amino acid loaded defective robust metal-organic frameworks. Nano Res. 2024, 17, 2004–2010.
Crossref Google Scholar
[53]

Li, Y. H.; Xiao, J. Z.; Guo, Y. Y.; Han, N.; Yuan, F. L.; Chen, Y. F.; Yao, M. S. Dynamic apertures with diffusion-regulatory functionality in soft porous crystals: A key to solving the century puzzle on isotopologues separation. Nano Res. 2023, 16, 3254–3255.
Crossref Google Scholar
[54]

Li, Y.; Ma, W. S.; Sun, J.; Lin, M.; Niu, Y. S.; Yang, X. C.; Xu, Y. H. Electrochemical generation of Fe3C/N-doped graphitic carbon nanozyme for efficient wound healing in vivo. Carbon 2020, 159, 149–160.
Crossref Google Scholar
[55]

Liu, Y. H.; Xu, B. L.; Lu, M. Z.; Li, S. S.; Guo, J.; Chen, F. Z.; Xiong, X. L.; Yin, Z.; Liu, H. Y.; Zhou, D. S. Ultrasmall Fe-doped carbon dots nanozymes for photoenhanced antibacterial therapy and wound healing. Bioact. Mater. 2022, 12, 246–256.
Crossref Google Scholar
[56]

Shakya, S.; He, Y. P.; Ren, X. H.; Guo, T.; Maharjan, A.; Luo, T.; Wang, T. T.; Dhakhwa, R.; Regmi, B.; Li, H. Y. et al. Ultrafine silver nanoparticles embedded in cyclodextrin metal-organic frameworks with GRGDS functionalization to promote antibacterial and wound healing application. Small 2019, 15, 1901065.
Crossref Google Scholar
[57]

Rasool, K.; Helal, M.; Ali, A.; Ren, C. E.; Gogotsi, Y.; Mahmoud, K. A. Antibacterial activity of Ti3C2T x MXene. ACS Nano 2016, 10, 3674–3684.
Crossref Google Scholar
[58]

Cao, X. W.; Zhu, C. X.; Hong, Q.; Chen, X. H.; Wang, K. Y.; Shen, Y. F.; Liu, S. Q.; Zhang, Y. J. Insight into iron leaching from an ascorbate-oxidase-like Fe-N-C nanozyme and oxygen reduction selectivity. Angew. Chem., Int. Ed. 2023, 62, e202302463.
Crossref Google Scholar
[59]

Liu, W. G.; Zhang, L. L.; Liu, X.; Liu, X. Y.; Yang, X. F.; Miao, S.; Wang, W. T.; Wang, A. Q.; Zhang, T. Discriminating catalytically active FeN x species of atomically dispersed Fe-N-C catalyst for selective oxidation of the C-H bond. J. Am. Chem. Soc. 2017, 139, 10790–10798.
Crossref Google Scholar
[60]

De Angelis, J.; Gastel, J.; Klein, D. C.; Cole, P. A. Kinetic analysis of the catalytic mechanism of serotonin N-acetyltransferase (EC 2.3.1.87). J. Biol. Chem. 1998, 273, 3045–3050.
Crossref Google Scholar
[61]

Zhu, C. X.; Zhou, Z. X.; Gao, X. J.; Tao, Y. H.; Cao, X. W.; Xu, Y.; Shen, Y. F.; Liu, S. Q.; Zhang, Y. J. Cascade nanozymatic network mimicking cells with selective and linear perception of H2O2. Chem. Sci. 2023, 14, 6780–6791.
Crossref Google Scholar
[62]

Hong, Q.; Yang, H.; Fang, Y. F.; Li, W.; Zhu, C. X.; Wang, Z.; Liang, S. C.; Cao, X. W.; Zhou, Z. X.; Shen, Y. F. et al. Adaptable graphitic C6N6-based copper single-atom catalyst for intelligent biosensing. Nat. Commun. 2023, 14, 2780.
Crossref Google Scholar
[63]

Zakharova, G. S.; Uporov, I. V.; Tishkov, V. I. Horseradish peroxidase: Modulation of properties by chemical modification of protein and heme. Biochemistry (Moscow) 2011, 76, 1391–1401.
Crossref Google Scholar
[64]

Li, G. M.; Liu, H.; Hu, T. D.; Pu, F.; Ren, J. S.; Qu, X. G. Dimensionality engineering of single-atom nanozyme for efficient peroxidase-mimicking. J. Am. Chem. Soc. 2023, 145, 16835–16842.
Crossref Google Scholar
[65]

Li, H. L.; Wang, L. B.; Dai, Y. Z.; Pu, Z. T.; Lao, Z. H.; Chen, Y. W.; Wang, M. L.; Zheng, X. S.; Zhu, J. F.; Zhang, W. H. et al. Synergetic interaction between neighbouring platinum monomers in CO2 hydrogenation. Nat. Nanotechnol. 2018, 13, 411–417.
Crossref Google Scholar
[66]

Lim, H.; Brueggemeyer, M. T.; Transue, W. J.; Meier, K. K.; Jones, S. M.; Kroll, T.; Sokaras, D.; Kelemen, B.; Hedman, B.; Hodgson, K. O. et al. Kβ X-ray emission spectroscopy of Cu(I)-lytic polysaccharide monooxygenase: Direct observation of the frontier molecular orbital for H2O2 activation. J. Am. Chem. Soc. 2023, 145, 16015–16025
Crossref Google Scholar
Nano Research
Volume 17 Issue 8,
August 2024
Pages 7427-7435
DOI: 10.1007/s12274-024-6699-x
Cite this article:
Wang X, Wang H, Zhang J, et al. Peroxidase-like active Cu-ZIF-8 with rich copper(I)-nitrogen sites for excellent antibacterial performances toward drug-resistant bacteria. Nano Research, 2024, 17(8): 7427-7435. https://doi.org/10.1007/s12274-024-6699-x
Topics:
Bactericides

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Received: 15 February 2024
Revised: 26 March 2024
Accepted: 08 April 2024
Published: 08 May 2024
© Tsinghua University Press 2024
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