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Research Article | Open Access

Mechanical property and biocompatibility of co-precipitated nano hydroxyapatite–gelatine composites

Huirong LEa( ), Kiruthika NATESANb, Sundaram PRANTI-HARANc
School of Marine Science and Engineering, Plymouth University, United Kingdom
Peninsular Schools of Medicine and Dentistry, Plymouth University, United Kingdom
School of Engineering, Physics and Mathematics, University of Dundee, United Kingdom
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Abstract

Uniform and well dispersed nano hydroxyapatite (HA)–gelatine composites were obtained by co-precipitation of hydroxyapatite and denatured calf skin collagen. The process allowed much higher concentration of hydroxyapatite to be produced over conventional hydrothermal process to improve the productivity. The effect of gelatine on the morphology, mechanical properties, and biocompatibility of hydroxyapatite particles was investigated. Fibroblast cell tests of the consolidated hydroxyapatite–gelatine composites showed that the composites have excellent biocompatibility.

Keywords

biomaterialsnanocompositeshydroxyapatite (HA)gelatinebiocompatibility

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Journal of Advanced Ceramics
Volume 4 Issue 3,
September 2015
Pages 237-243
DOI: 10.1007/s40145-015-0155-z
Cite this article:
LE H, NATESAN K, PRANTI-HARAN S. Mechanical property and biocompatibility of co-precipitated nano hydroxyapatite–gelatine composites. Journal of Advanced Ceramics, 2015, 4(3): 237-243. https://doi.org/10.1007/s40145-015-0155-z

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Received: 01 April 2015
Revised: 20 April 2015
Accepted: 03 May 2015
Published: 07 July 2015
© The author(s) 2015

Open Access: This article is distributed under the terms of the Creative Commons Attribution License which permits any use, distribution, and reproduction in any medium, provided the original author(s) and the source are credited.
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