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Research paper | Open Access

Rice melatonin deficiency causes premature leaf senescence via DNA methylation regulation

Yue Lua,b,1, Ahmed Ghariba,c,1, Rujia Chena,b,1, Hanyao Wanga,b, Tianyun Taoa,b, Zhihao Zuoa,b, Qing Bua,b, Yanze Sua,b, Yaoqing Lia,b, Yanmo Luoa,b, Hamdi F. El-Mowafid, Zhichao Wanga,b, Qianfeng Huanga,b, Shuting Wanga,b, Yang Xua,b, Pengcheng Lia,b, Chenwu Xua,b( ), Zefeng Yanga,b( )
Jiangsu Key Laboratory of Crop Genomics and Molecular Breeding/Zhongshan Biological Breeding Laboratory/Key Laboratory of Plant Functional Genomics of the Ministry of Education, Agriculture College of Yangzhou University, Yangzhou 225009, Jiangsu, China
Jiangsu Co-Innovation Center for Modern Production Technology of Grain Crops, Jiangsu Key Laboratory of Crop Genetics and Physiology, Yangzhou University, Yangzhou 225009, Jiangsu, China
National Institute of Laser Enhanced Sciences (NILES), Cairo University, Giza 12613, Egypt
Rice Research Department, Field Crops Research Institute, Agricultural Research Center, Sakha, Kafr El-Sheikh 33717, Egypt

1 These authors contributed equally to this work.

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Abstract

In a study of DNA methylation changes in melatonin-deficient rice mutants, mutant plants showed premature leaf senescence during grain-filling and reduced grain yield. Melatonin deficiency led to transcriptional reprogramming, especially of genes involved in chlorophyll and carbon metabolism, redox regulation, and transcriptional regulation, during dark-induced leaf senescence. Hypomethylation of mCG and mCHG in the melatonin-deficient rice mutants was associated with the expression change of both protein-coding genes and transposable element-related genes. Changes in gene expression and DNA methylation in the melatonin-deficient mutants were compensated by exogenous application of melatonin. A decreased S-adenosyl-L-methionine level may have contributed to the DNA methylation variations in rice mutants of melatonin deficiency under dark conditions.

Keywords

DNA methylationMelatoninRiceEpigenetic regulationPremature leaf senescence

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The Crop Journal
Volume 12 Issue 3,
June 2024
Pages 721-731
DOI: 10.1016/j.cj.2024.04.004
Cite this article:
Lu Y, Gharib A, Chen R, et al. Rice melatonin deficiency causes premature leaf senescence via DNA methylation regulation. The Crop Journal, 2024, 12(3): 721-731. https://doi.org/10.1016/j.cj.2024.04.004

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Received: 26 January 2024
Revised: 31 March 2024
Accepted: 22 April 2024
Published: 13 May 2024
© 2024 Crop Science Society of China and Institute of Crop Science, CAAS.

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
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