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Research Article | Open Access

Simultaneous determination of 15 pesticide residues in Chinese cabbage and cucumber by liquid chromatography-tandem mass spectrometry utilizing online turbulent flow chromatography

Sufang Fana,b, Junmei Mab, Meirong Caob, Juan Wangb, Leilei Zhangb, Yan Zhanga,b( ), Qiang Lib( ), Jia Chenc
Hebei Key Laboratory of Forensic Medicine, College of Forensic Medicine, Hebei Medical University, Shijiazhuang 050017, China
Hebei Food Safety Key Laboratory, Hebei Food Inspection and Research Institute, 050227, Shijiazhuang, China
College of Food Science and Technology, Hebei Agricultural University, 071001, Baoding, China
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Abstract

In this experiment, a liquid chromatography tandem mass spectrometry method was built to determine 15 pesticide residues in Chinese cabbage and cucumber samples based on online turbulent flow chromatography purification. After modified quick, easy, cheap, effective, rugged, and safe (QuEChERS) extraction, extracts were directly injected to the TLX (TurboFlow Liquid Xcalibur) system and brought to TurboFlowTM columns for on-line purification and then transferred to analytical column for further separation and analysis. TurboFlowTM columns types, transfer flow rate, and transfer time were optimized. Limits of detection and limits of quantification of the method obtained for 15 pesticide residues were ranged between 0.2–1.0 μg/kg and 0.5–2.0 μg/kg in Chinese cabbage and cucumber samples. Recoveries of pesticide residues were in range of 75.3%–103.7%. Matrix effects for 15 pesticides were in range of 5.6%–106.6%. The developed method has been successfully used for the determination of 15 pesticide residues in real samples.

Keywords

Pesticide residuesOnline turbulent flow chromatographyLiquid chromatography-tandem mass spectrometry

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Food Science and Human Wellness
Volume 10 Issue 1,
January 2021
Pages 78-86
DOI: 10.1016/j.fshw.2020.06.003
Cite this article:
Fan S, Ma J, Cao M, et al. Simultaneous determination of 15 pesticide residues in Chinese cabbage and cucumber by liquid chromatography-tandem mass spectrometry utilizing online turbulent flow chromatography. Food Science and Human Wellness, 2021, 10(1): 78-86. https://doi.org/10.1016/j.fshw.2020.06.003

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Received: 27 February 2020
Revised: 26 April 2020
Accepted: 01 June 2020
Published: 26 July 2020
© 2021 Beijing Academy of Food Sciences. Production and hosting by Elsevier B.V. on behalf of KeAi Communications Co., Ltd.

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
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