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Review Article | Open Access

The role of glutamine in supporting gut health and neuropsychiatric factors

Brett J. Deters, Mir Saleem( )
Halmos College of Natural Sciences and Oceanography, NOVA Southeastern University, Fort Lauderdale, FL 33314 USA

Peer review under responsibility of KeAi Communications Co., Ltd

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Abstract

Recent research has shown that the amino acid glutamine can positively affect gut health by supporting the gut microbiome, gut mucosal wall integrity, and by modulating inflammatory responses. As modulated by the vagus nerve, via the enteric nervous system, the gut-brain connection can impact the brain's neurochemical environment. Poor gut health can disrupt the balance of neurotransmitters, which can result in neuropsychiatric based conditions such as depression. Glutamine supplementation may provide significant adjunctive nutritional support in cases of depression by promoting proper gut health and function.

Keywords

MicrobiomeGutGlutamineNeuropsychiatryEnteric nervous systemNeurotransmitters

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Food Science and Human Wellness
Volume 10 Issue 2,
March 2021
Pages 149-154
DOI: 10.1016/j.fshw.2021.02.003
Cite this article:
Deters BJ, Saleem M. The role of glutamine in supporting gut health and neuropsychiatric factors. Food Science and Human Wellness, 2021, 10(2): 149-154. https://doi.org/10.1016/j.fshw.2021.02.003

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Received: 28 March 2020
Revised: 26 June 2020
Accepted: 27 June 2020
Published: 22 March 2021
© 2021 Beijing Academy of Food Sciences.

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
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