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Research Article | Open Access

Highly-sensitive electrochemiluminescence biosensor for detection of inosine monophosphate in meat based on graphdiyne/AuNPs/luminol nanocomposites

Jing Liua,1, Yizhong Shenb,1, Guangxian Wanga, Yaodong Xianga, Yemin Guoa, Xia Suna( ), Yuan Liuc( )
School of Agricultural Engineering and Food Science, Shandong University of Technology, Zibo 255049, China
School of Food and Biological Engineering, Hefei University of Technology, Hefei 230009, China
School of Agriculture and Biology, Shanghai Jiao Tong University, Shanghai 200240, China

1 These authors contribute equally to this paper and should be considered as co-first author.Peer review under responsibility of KeAi Communications Co., Ltd.]]>

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Abstract

Inosine monophosphate (IMP), as a critical umami substance, is one of the most important indicators for evaluating the quality of meat products. Here, a sensitive electrochemiluminescence (ECL) biosensor based on graphdiyne (GDY)/AuNPs/luminol nanocomposites was constructed to detect IMP. The GDY/AuNPs/luminol nanocomposites were synthesized by using simple one-pot method. GDY utilized its 2D framework to disperse and fix gold nanoparticles, which inhibited the agglomeration of gold nanoparticles and greatly improved its stability and catalytic properties. Importantly, GDY/AuNPs/luminol nanocomposites showed excellent catalytic ability and superior ECL activity towards luminol-H2O2 systems due to the synergistic effect of GDY and AuNPs. Under optimal conditions, the prepared biosensor exhibited a wide linear range from 0.01 g/L to 20 g/L, a satisfactory limit detection of 0.0013 g/L, as well as an excellent specificity. Moreover, we carried out the precise analysis of IMP in actual meat samples with acceptable results compared to the liquid chromatography. We believe that this work could offer an efficient ECL platform for accurate and reliable report of IMP levels, which is significant for maintaining food quality and safety.

Keywords

Inosine monophosphate (IMP)ElectrochemiluminescenceGraphdiyne (GDY)/AuNPs/luminolBienzyme

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Food Science and Human Wellness
Volume 12 Issue 4,
July 2023
Pages 1149-1156
DOI: 10.1016/j.fshw.2022.10.040
Cite this article:
Liu J, Shen Y, Wang G, et al. Highly-sensitive electrochemiluminescence biosensor for detection of inosine monophosphate in meat based on graphdiyne/AuNPs/luminol nanocomposites. Food Science and Human Wellness, 2023, 12(4): 1149-1156. https://doi.org/10.1016/j.fshw.2022.10.040

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Received: 14 May 2021
Revised: 18 July 2021
Accepted: 04 August 2021
Published: 18 November 2022
© 2023 Beijing Academy of Food Sciences. Publishing services by Elsevier B.V. on behalf of KeAi Communications Co., Ltd.

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
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