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Rapid Communication | Open Access

The single-cell landscape reveals unique tumor subsets and microenvironments associated with poor clinical outcomes in primary testicular diffuse large B-cell lymphoma

Zhouliang Biana,b,1Benhong Guc,1Guohai Shid,e,1Jiahui Guoa,bDong LicHanlin Zenga,bBin Jianga()Daliu Minf()Hengchuan Sud,e()Yanjie Zhanga,b()
Department of Oncology, Ninth People’s Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 201900, China
Shanghai Institute of Precision Medicine, Ninth People’s Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200125, China
Department of Urology, Tongren Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200336, China
Department of Urology, Fudan University Shanghai Cancer Center, Shanghai 200032, China
Department of Oncology, Shanghai Medical College, Fudan University, Shanghai 200032, China
Department of Oncology, Shanghai Jiao Tong University Affiliated Sixth People’s Hospital, Shanghai 200233, China

1 These authors contributed equally to this work.

Peer review under responsibility of Chongqing Medical University.

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References

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Pollari M, Leivonen SK, Leppä S. Testicular diffuse large B-cell lymphoma-clinical, molecular, and immunological features. Cancers. 2021;13(16):4049.

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Takahashi H, Tomita N, Yokoyama M, et al. Prognostic impact of extranodal involvement in diffuse large B-cell lymphoma in the rituximab era. Cancer. 2012;118(17):4166-4172.

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Venturutti L, Melnick AM. The dangers of déjà vu: memory B cells as the cells of origin of ABC-DLBCLs. Blood. 2020;136(20):2263-2274.

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Steen CB, Luca BA, Esfahani MS, et al. The landscape of tumor cell states and ecosystems in diffuse large B cell lymphoma. Cancer Cell. 2021;39(10):1422-1437.

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Xu-Monette ZY, Møller MB, Tzankov A, et al. MDM2 phenotypic and genotypic profiling, respective to TP53 genetic status, in diffuse large B-cell lymphoma patients treated with rituximab-CHOP immunochemotherapy: a report from the International DLBCL Rituximab-CHOP Consortium Program. Blood. 2013;122(15):2630-2640.

Genes & Diseases
Pages 80-83
Cite this article:
Bian Z, Gu B, Shi G, et al. The single-cell landscape reveals unique tumor subsets and microenvironments associated with poor clinical outcomes in primary testicular diffuse large B-cell lymphoma. Genes & Diseases, 2024, 11(1): 80-83. https://doi.org/10.1016/j.gendis.2023.02.036
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