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Rapid Communication | Open Access

Aldh2 deficiency plays a dual role in lung tumorigenesis and tumor progression

Hongjia Zhanga,b,c,,1, Xueqian Sund,1, Zhanming Lie,1, Tingting Liud, Fang Zhangf, Xinyu Mengd, Kaimi Lig, Jianhua Xua,c, Wei Hea,c, Bo Jingh, Tong Wangi, Na Nid, Beibei Sunj, Feng Yaoj, Yadi Wuk, Qi Wangm, Jing Dud, Eugene Y. Chinn, Binhua P. Zhouk, Ping Jiangc, Lishun Wange( ), Jiong Denga,b,d,n( )
Key Laboratory of Cell Differentiation and Apoptosis of Chinese Minister of Education, Department of Pathophysiology, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China
Shanghai Key Laboratory for Tumor Microenvironment and Inflammation, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China
Department of Pathology, Kunming Medical University, Kunming, Yunnan 650500, China
Medical Research Center, Binzhou Medical University Hospital, Binzhou, Shandong 256600, China
Center for Traditional Chinese Medicine and Gut Microbiota, Minhang Hospital, Fudan University, Shanghai 201100, China
Department of Radiation Oncology, Yantai Affiliated Hospital of Binzhou Medical University, Yantai, Shandong 264100, China
Department of Pathology, Molecular Pathology Research Center, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100730, China
Department of Laboratory Medicine, Shanghai Pulmonary Hospital Affiliated Tongji University, Shanghai 200080, China
Department of Physiology, School of Basic Medical Sciences, Weifang Medical University, Weifang, Shandong 261021, China
Department of Thoracic Surgery, Shanghai Chest Hospital, Shanghai Jiao Tong University, Shanghai 200030, China
Department of Molecular and Cellular Biochemistry, Markey Cancer Center, University of Kentucky College of Medicine, Lexington, KY 40506, USA
Department of Respiratory Medicine, The Second Affiliated Hospital, Dalian Medical University, Dalian, Liaoning 116023, China
Peninsular Cancer Center, Binzhou Medical University, Yantai, Shandong 264003, China

Peer review under responsibility of Chongqing Medical University.

1 These authors contributed equally to this work.

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References

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Genes & Diseases
Volume 11 Issue 3,
May 2024
Article number: 100999
DOI: 10.1016/j.gendis.2023.04.030
Cite this article:
Zhang H, Sun X, Li Z, et al. Aldh2 deficiency plays a dual role in lung tumorigenesis and tumor progression. Genes & Diseases, 2024, 11(3): 100999. https://doi.org/10.1016/j.gendis.2023.04.030

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Received: 07 January 2023
Published: 24 June 2023
© 2023 The Authors.

This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
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