Mechanical sensor PDLIM5 promotes the osteogenesis of human adipose-derived stem cells through microfilament alterations

Yuchao Yang; Shutong Wu; Rongmei Qu; Congrong Wang; Jinyang Wang; Asmat Ullah Khan; You Pan; Wenqing Liu; Jinhui Zhu; Muhammad Akram Khan; Chujiang Xu; Jingxing Dai; Jun Ouyang

doi:10.1016/j.gendis.2023.06.001

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Rapid Communication | Open Access

Mechanical sensor PDLIM5 promotes the osteogenesis of human adipose-derived stem cells through microfilament alterations

Yuchao Yang^{^a^,¹}, Shutong Wu^{^a^,¹}, Rongmei Qu^{^a}, Congrong Wang^{^b}, Jinyang Wang^{^c}, Asmat Ullah Khan^{^a}, You Pan^{^d}, Wenqing Liu^{^a}, Jinhui Zhu^{^a}, Muhammad Akram Khan^{^e}, Chujiang Xu^{^f}, Jingxing Dai^{^a}(), Jun Ouyang^{^a}()

Guangdong Provincial Key Laboratory of Medical Biomechanics & National Key Discipline of Human Anatomy, School of Basic Medical Sciences, Southern Medical University, Guangzhou, Guangdong 510515, China

Department of Laboratory Medicine, Nanfang Hospital of Southern Medical University, Guangzhou, Guangdong 510515, China

Department of Pathology, Guangdong Provincial People’s Hospital, Guangdong Academy of Medical Sciences, Guangzhou, Guangdong 510080, China

Department of Breast Surgery, Guangxi Medical University Cancer Hospital, Nanning, Guangxi 530000, China

Department of Veterinary Pathology, Faculty of Veterinary and Animal Sciences, PMAS Arid Agriculture University, Rawalpindi 46300, Pakistan

Department of Orthopedics, TCM-Integrated Hospital, Southern Medical University, Guangzhou, Guangdong 510000, China

¹ These authors contributed equally to this work.

Peer review under responsibility of Chongqing Medical University.

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References

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Genes & Diseases

Volume 11 Issue 3,
May 2024

Article number: 101023

DOI: 10.1016/j.gendis.2023.06.001

Cite this article:

Yang Y, Wu S, Qu R, et al. Mechanical sensor PDLIM5 promotes the osteogenesis of human adipose-derived stem cells through microfilament alterations. Genes & Diseases, 2024, 11(3): 101023. https://doi.org/10.1016/j.gendis.2023.06.001