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Rapid Communication | Open Access

SPNS1 ablation drives skeletal muscle atrophy by disrupting mitophagy, mitochondrial function, and apoptosis in mice

Xianzhong Zhanga,1, Fengmin Zhanga,1, Haofan Wua,b, Zhen Yua, Chengle Zhuanga,b( )
Department of Gastrointestinal Surgery, Shanghai Tenth People’s Hospital, School of Medicine, Tongji University, Shanghai 200092, China
Colorectal Cancer Center, Shanghai Tenth People’s Hospital, School of Medicine, Tongji University, Shanghai 200072, China

1 These authors contributed equally to this work.

Peer review under responsibility of Chongqing Medical University.

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He M, Kuk ACY, Ding M, et al. Spns1 is a lysophospholipid transporter mediating lysosomal phospholipid salvage. Proc Natl Acad Sci U S A. 2022;119(40):e2210353119.
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Genes & Diseases
Volume 11 Issue 5,
September 2024
Article number: 101083
DOI: 10.1016/j.gendis.2023.101083
Cite this article:
Zhang X, Zhang F, Wu H, et al. SPNS1 ablation drives skeletal muscle atrophy by disrupting mitophagy, mitochondrial function, and apoptosis in mice. Genes & Diseases, 2024, 11(5): 101083. https://doi.org/10.1016/j.gendis.2023.101083

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Received: 09 February 2023
Published: 07 September 2023
© 2023 The Authors.

This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
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