AI Chat Paper
Note: Please note that the following content is generated by AMiner AI. SciOpen does not take any responsibility related to this content.
{{lang === 'zh_CN' ? '文章概述' : 'Summary'}}
{{lang === 'en_US' ? '中' : 'Eng'}}
Chat more with AI
Powered by AMiner. Clicking this button will take you away from SciOpen.
Home Genes & Diseases Article
PDF (847.1 KB)
Cite
EndNote(RIS) BibTeX
Collect
Submit Manuscript AI Chat Paper
Show Outline
Outline
Show full outline
Hide outline
Outline
Show full outline
Hide outline
Rapid Communication | Open Access

MPZL1 as an HGF/MET signaling amplifier promotes cell migration and invasion in glioblastoma

Haimin Songa,1, Bowen Nib,1, Xuetao Pengc, Weijuan Xud, Shaochun Yanga, Runwei Yange, Ziyu Wangb, Kaishu Lif, Rui Ling, Yunxiao Zhange, Jinglin Guoe, Kezhi Wub, Guangwei Shib, Jichao Sunh, Chunming Hea( ), Yawei Liub( )
Department of Neurosurgery, The First Affiliated Hospital of Gannan Medical University, Ganzhou, Jiangxi 341000, China
Department of Neurosurgery & Medical Research Center, Shunde Hospital, Southern Medical University (The First People's Hospital of Shunde Foshan), Foshan, Guangdong 528300, China
Medical Research Center, Shunde Hospital, Southern Medical University (The First People's Hospital of Shunde Foshan), Foshan, Guangdong 528300, China
Bidding and Procurement Office, Shunde Hospital, Southern Medical University (The First People's Hospital of Shunde Foshan), Foshan, Guangdong 528300, China
Department of Neurosurgery, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong 510515, China
Department of Neurosurgery, The Sixth Affiliated Hospital of Guangzhou Medical University, Qingyuan, Guangdong 511518, China
Department of Neurosurgery, The First Affiliated Hospital of Shantou University Medical College, Shantou, Guangdong 515041, China
Department of Geriatrics, Shenzhen People's Hospital (The Second Clinical Medical College, Jinan University; The First Affiliated Hospital, Southern University of Science and Technology), Shenzhen, Guangdong 518020, China

1 These authors contributed equally to the work.

Peer review under responsibility of Chongqing Medical University.

Show Author Information

References

1

Sa JK, Kim SH, Lee JK, et al. Identification of genomic and molecular traits that present therapeutic vulnerability to HGF-targeted therapy in glioblastoma. Neuro Oncol. 2019;21(2):222-233.
Crossref Google Scholar
2

Shi X, Wang M, Zhang Y, et al. Hypoxia activated HGF expression in pancreatic stellate cells confers resistance of pancreatic cancer cells to EGFR inhibition. EBioMedicine. 2022;86:104352.
Crossref Google Scholar
3

Cloughesy T, Finocchiaro G, Belda-Iniesta C, et al. Randomized, double-blind, placebo-controlled, multicenter phase II study of onartuzumab plus bevacizumab versus placebo plus bevacizumab in patients with recurrent glioblastoma: efficacy, safety, and hepatocyte growth factor and O6-methylguanine-DNA methyltransferase biomarker analyses. J Clin Oncol. 2017;35(3):343-351.
Crossref Google Scholar
4

Wen PY, Drappatz J, de Groot J, et al. Phase II study of cabozantinib in patients with progressive glioblastoma: subset analysis of patients naive to antiangiogenic therapy. Neuro Oncol. 2018;20(2):249-258.
Crossref Google Scholar
5

Kelley LA, Mezulis S, Yates CM, Wass MN, Sternberg MJE. The Phyre2 web portal for protein modeling, prediction and analysis. Nat Protoc. 2015;10(6):845-858.
Crossref Google Scholar
Genes & Diseases
Volume 11 Issue 5,
September 2024
Article number: 101085
DOI: 10.1016/j.gendis.2023.101085
Cite this article:
Song H, Ni B, Peng X, et al. MPZL1 as an HGF/MET signaling amplifier promotes cell migration and invasion in glioblastoma. Genes & Diseases, 2024, 11(5): 101085. https://doi.org/10.1016/j.gendis.2023.101085

131

Views

0

Downloads

0

Crossref

1

Web of Science

1

Scopus

0

CSCD

Altmetrics
Received: 25 April 2023
Published: 09 September 2023
© 2023 The Authors.

This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
Return