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Letter | Open Access

Comprehensive characterization of cell disulfidptosis in human cancers: An integrated pan-cancer analysis

Guo Zhao1Yale Jiang1Yuning Wang1Shuhang Wang( )Ning Li( )
Clinical Trial Center, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China

Peer review under responsibility of Chongqing Medical University.

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References

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Liu X, Olszewski K, Zhang Y, et al. Cystine transporter regulation of pentose phosphate pathway dependency and disulfide stress exposes a targetable metabolic vulnerability in cancer. Nat Cell Biol. 2020;22(4):476–486.

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Joly JH, Delfarah A, Phung PS, Parrish S, Graham NA. A synthetic lethal drug combination mimics glucose deprivation-induced cancer cell death in the presence of glucose. J Biol Chem. 2020;295(5):1350–1365.

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Liu X, Nie L, Zhang Y, et al. Actin cytoskeleton vulnerability to disulfide stress mediates disulfidptosis. Nat Cell Biol. 2023;25(3):404–414.

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Tong X, Tang R, Xiao M, et al. Targeting cell death pathways for cancer therapy: recent developments in necroptosis, pyroptosis, ferroptosis, and cuproptosis research. J Hematol Oncol. 2022;15(1):174.

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Á Bartha, Győrffy B. Comprehensive outline of whole exome sequencing data analysis tools available in clinical oncology. Cancers. 2019;11(11):1725.

Genes & Diseases
Article number: 101095
Cite this article:
Zhao G, Jiang Y, Wang Y, et al. Comprehensive characterization of cell disulfidptosis in human cancers: An integrated pan-cancer analysis. Genes & Diseases, 2024, 11(4): 101095. https://doi.org/10.1016/j.gendis.2023.101095

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Received: 25 May 2023
Published: 14 September 2023
© 2024 The Authors.

This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).

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