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Rapid Communication | Open Access

Serum metabolic profiling implicates mTOR activation and insulin resistance in the development of pulmonary hypertension in a rat model of pressure overload-induced heart failure

Qi Zhoua, Chao Tangb, Xinke Xub, Junhao Huc, Shengsen Yaob, Bo Dongb, Xiaojing Wub( )
Department of Cardiology of the Fifth Affiliated Hospital of Southern Medical University, Guangzhou, Guangdong 510999, China
Cardiovascular Department of Shenzhen University General Hospital, Shenzhen, Guangdong 518055, China
Cardiovascular Department of Chongqing Medical University Second Affiliated Hospital, Chongqing 400010, China

Peer review under responsibility of Chongqing Medical University.

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Arner P, Rydén M. Fatty acids, obesity and insulin resistance. Obes Facts. 2015;8(2):147–155.
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Genes & Diseases
Volume 11 Issue 5,
September 2024
Article number: 101097
DOI: 10.1016/j.gendis.2023.101097
Cite this article:
Zhou Q, Tang C, Xu X, et al. Serum metabolic profiling implicates mTOR activation and insulin resistance in the development of pulmonary hypertension in a rat model of pressure overload-induced heart failure. Genes & Diseases, 2024, 11(5): 101097. https://doi.org/10.1016/j.gendis.2023.101097

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Received: 02 June 2023
Published: 14 September 2023
© 2023 The Authors.

This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
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