AI Chat Paper
Note: Please note that the following content is generated by AMiner AI. SciOpen does not take any responsibility related to this content.
{{lang === 'zh_CN' ? '文章概述' : 'Summary'}}
{{lang === 'en_US' ? '中' : 'Eng'}}
Chat more with AI
PDF (1.3 MB)
Collect
Submit Manuscript AI Chat Paper
Show Outline
Outline
Show full outline
Hide outline
Outline
Show full outline
Hide outline
Rapid Communication | Open Access

EZH2 is a prognostic factor associated with tumor stemness and immune infiltration in skull base chordoma

Qian Liua,b,1Mingxuan Lib,1Yujia Xionga,1Yutao ShenaTianshun MaaTianhao ZhangaXiaohong R. YangcYazhuo Zhanga,b( )Jiwei Baia,b( )
Beijing Neurosurgical Institute, Capital Medical University, Beijing 100070, China
Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing 100070, China
Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, Bethesda, MD 20892, USA

Peer review under responsibility of Chongqing Medical University.

1 These authors contributed equally to this work.

Show Author Information

References

1

Duan R, Du W, Guo W. EZH2: a novel target for cancer treatment. J Hematol Oncol. 2020;13(1):104.

2

Peng D, Kryczek I, Nagarsheth N, et al. Epigenetic silencing of TH1-type chemokines shapes tumour immunity and immunotherapy. Nature. 2015;527(7577):249-253.

3

Yin Y, Qiu S, Li X, Huang B, Xu Y, Peng Y. EZH2 suppression in glioblastoma shifts microglia toward M1 phenotype in tumor microenvironment. J Neuroinflammation. 2017;14(1):220.

4

Bai J, Shi J, Zhang Y, et al. Gene expression profiling identifies two chordoma subtypes associated with distinct molecular mechanisms and clinical outcomes. Clin Cancer Res. 2023;29(1):261-270.

5

Bai J, Shi J, Li C, et al. Whole genome sequencing of skull-base chordoma reveals genomic alterations associated with recurrence and chordoma-specific survival. Nat Commun. 2021;12:757.

Genes & Diseases
Article number: 101133
Cite this article:
Liu Q, Li M, Xiong Y, et al. EZH2 is a prognostic factor associated with tumor stemness and immune infiltration in skull base chordoma. Genes & Diseases, 2024, 11(5): 101133. https://doi.org/10.1016/j.gendis.2023.101133

145

Views

0

Downloads

0

Crossref

0

Web of Science

0

Scopus

0

CSCD

Altmetrics

Received: 21 May 2023
Published: 11 October 2023
© 2023 The Authors.

This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).

Return