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Rapid Communication | Open Access

The efficacy and safety of NeuroWell antidepressant dietary supplement, Deanxit, and their combination in the treatment of mild-to-moderate depression: A randomized clinical trial

Honglei Yina,1, Zhuxin Suib,1, Yutong Wangc, Dechen Liud, Qinglu Wange, Yanchao Wanga, Lei Suna, Jinfeng Lif, Zhen Lib, Yue Liug, Shang Guoh, Wenwen Wangi, Hongtao Yinj, Ping Liuj, Kezhong Zhangk, Huaibo Zhangm, Yajun Liua, Yanqiu Liua, Qiqi Zhoun, Dianfang Weib, Hui Zhanga, Shanshan Wanga, Yaochao Ningo, Shuang Genga, Xuejun Wenp,q,r,s,t( ), Youping Dengu( ), Hongwei Wangv( ), Yunliang Wanga,w( )
Neurology Department, ZiBo 148 Hospital, China RongTong Medical Healthcare Group Co., Ltd., Zibo, Shandong 255300, China
Department of Histology and Embryology, Teaching Department of Basic Medicine, Qilu Medical University, Zibo, Shandong 255300, China
School of Public Health and Laboratory, Qilu Medical University, Zibo, Shandong 255300, China
School of Medicine, The Henan University of Chinese Medicine, Zhengzhou, Henan 450046, China
College of Sport and Health, Shandong Sport University, Jinan, Shandong 250102, China
Institute of Oncology, The Fifth Medical Centre, Chinese PLA General Hospital, Beijing 100071, China
School of Nursing, Qilu Medical University, Zibo, Shandong 255300, China
Department of Orthopedic Surgery, Shanghai Sixth People’s Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai 200023, China
Office of Infection Prevention and Control, The Fifth Clinical Medical College of Henan University of Chinese Medicine (Zhengzhou People’s Hospital), Zhengzhou, Henan 450002, China
Department of Neurology, Zibo Central Hospital, Zibo, Shandong 255036, China
Department of Neurology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu 210029, China
Research Assistant Professor Center for Alcohol Research in Epigenetics, Department of Psychiatry, University of Illinois at Chicago, Chicago, IL 60612, USA
Department of Pharmacology, School of Pharmacy, Qilu Medical University, Zibo, Shandong 255300, China
Department of Rehabilitation Medicine, Zibo First Hospital, Zibo, Shandong 255200, China
XREGEN Research Institute, Hangzhou, Zhejiang 310056, China
School of Life Sciences, Zhengzhou University, Zhengzhou, Henan 450001, China
Key Laboratory of Spine and Spinal Cord Injury Repair and Regeneration of Ministry of Education, Orthopedic Department of Tongji Hospital, School of Life Science and Technology, Tongji University, Shanghai 200065, China
International Institute for Biomedical Biomaterials (I2BM), Zhengzhou, Henan 450018, China
Department of Chemical and Life Science Engineering, School of Engineering, Virginia Commonwealth University, Richmond, VA 23284, USA
Department of Quantitative Health Sciences, John A. Burns School of Medicine, University of Hawaii at Manoa, Honolulu, HI 96813, USA
Department of Medicine, The University of Chicago, Chicago, IL 60637, USA
Neurology Department, The Second Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan 450014, China

1 These authors contributed equally to this work.

Peer review under responsibility of Chongqing Medical University.

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Genes & Diseases
Volume 11 Issue 6,
November 2024
Article number: 101171
DOI: 10.1016/j.gendis.2023.101171
Cite this article:
Yin H, Sui Z, Wang Y, et al. The efficacy and safety of NeuroWell antidepressant dietary supplement, Deanxit, and their combination in the treatment of mild-to-moderate depression: A randomized clinical trial. Genes & Diseases, 2024, 11(6): 101171. https://doi.org/10.1016/j.gendis.2023.101171

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Received: 28 June 2023
Published: 13 December 2023
© 2024 The Authors.

This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
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