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Rapid Communication | Open Access

TULP4 degrades RYBP to enhance DNA damage repair and chemosensitivity of pancreatic ductal adenocarcinoma

Jingyao Daia,1, Su Liub,1, Yangyang Xiec, Yixuan Wangc, Xiyun Biand, Tian Yud, Tiantian Lic, Linchuang Jiac, Zhigang Zhaob,e(), Zhiqiang Liub(), Xiaozhi Liud()
Hepatobiliary Surgery Department, Air Force Medical Center, Beijing 100142, China
Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Tianjin Key Laboratory of Cancer Prevention and Therapy, Tianjin’s Clinical Research Center for Cancer, Tianjin 300060, China
Department of Pathophysiology, School of Basic Medical Science, Tianjin Medical University, Tianjin 300060, China
Tianjin Key Laboratory of Epigenetics for Organ Development in Preterm Infants, Tianjin Fifth Central Hospital, Tianjin 300450, China
Department of Medical Oncology, Tianjin First Central Hospital, School of Medicine, Nankai University, Tianjin 300192, China

1 These authors contribute equally to this work.

Peer review under responsibility of Chongqing Medical University.

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Genes & Diseases
Volume 12 Issue 2,
March 2025
Article number: 101288
DOI: 10.1016/j.gendis.2024.101288
Cite this article:
Dai J, Liu S, Xie Y, et al. TULP4 degrades RYBP to enhance DNA damage repair and chemosensitivity of pancreatic ductal adenocarcinoma. Genes & Diseases, 2025, 12(2): 101288. https://doi.org/10.1016/j.gendis.2024.101288
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