PinX1 suppresses cancer progression by inhibiting telomerase activity in cervical squamous cell carcinoma and endocervical adenocarcinoma

Yue Weng; Xiangyu Yan; Biying Chen; Zhouliang Bian; Yunhui Ge; Hong Lu; Shufang He; Jian Wu; Yong Chen; Ming Lei; Yanjie Zhang

doi:10.1016/j.gendis.2024.101319

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PinX1 suppresses cancer progression by inhibiting telomerase activity in cervical squamous cell carcinoma and endocervical adenocarcinoma

Yue Weng^{^a^,^b^,¹}, Xiangyu Yan^{^a^,^b^,¹}, Biying Chen^{^a^,^b^,^c}, Zhouliang Bian^{^a^,^b^,^c}, Yunhui Ge^{^a^,^b}, Hong Lu^{^a^,^b}, Shufang He^{^a^,^b}, Jian Wu^{^a^,^b}, Yong Chen^{^d^,^e^,^f}(), Ming Lei^{^a^,^b}(), Yanjie Zhang^{^a^,^b^,^c}()

Shanghai Institute of Precision Medicine, Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200125, China

State Key Laboratory of Oncogenes and Related Genes, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China

Department of Oncology, Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 201900, China

State Key Laboratory of Molecular Biology, Shanghai Institute of Biochemistry and Cell Biology, Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences, Shanghai 200031, China

University of Chinese Academy of Sciences, Beijing 100049, China

School of Life Science and Technology, ShanghaiTech University, Shanghai 201210, China

Peer review under responsibility of Chongqing Medical University.

¹ These authors contributed equally to this work.

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References

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Genes & Diseases

Volume 12 Issue 2,
March 2025

Article number: 101319

DOI: 10.1016/j.gendis.2024.101319

Cite this article:

Weng Y, Yan X, Chen B, et al. PinX1 suppresses cancer progression by inhibiting telomerase activity in cervical squamous cell carcinoma and endocervical adenocarcinoma. Genes & Diseases, 2025, 12(2): 101319. https://doi.org/10.1016/j.gendis.2024.101319