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Rapid Communication | Open Access

SIK2 promotes malignant features of human osteosarcoma via up-regulating MMP2 and β-catenin expression

Yutong Wanga,1, Yulan Yaob,1, Sen Kouc, Shanshan Wangc, Juntao Songd, Siqi Yangc, Hongwei Wange( ), Yunliang Wangb,c( )
School of Public Health and Laboratory of Qilu Medical University, Zibo, Shandong 255300, China
Department of Neurology, The Second Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan 450014, China
Department of Neurology, Zibo 148 Hospital, Zibo, Shandong 255300, China
Department of Oncology and Hematology, Zibo 148 Hospital, Zibo, Shandong 255300, China
School of Pharmacy, Nanjing Medical University, Nanjing, Jiangsu 211166, China

Peer review under responsibility of Chongqing Medical University.

1 Yutong Wang and Yulan Yao are co-first authors.

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Genes & Diseases
Volume 12 Issue 2,
March 2025
Article number: 101325
DOI: 10.1016/j.gendis.2024.101325
Cite this article:
Wang Y, Yao Y, Kou S, et al. SIK2 promotes malignant features of human osteosarcoma via up-regulating MMP2 and β-catenin expression. Genes & Diseases, 2025, 12(2): 101325. https://doi.org/10.1016/j.gendis.2024.101325

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Received: 06 December 2023
Published: 26 June 2024
© 2024 The Authors.

This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
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