Actin polymerization regulates the osteogenesis of hASCs by influencing α-tubulin expression and Eg5 activity

Tingyu Fan; Wenqing Liu; Rongmei Qu; Jinhui Zhu; Yulian Shi; Jiaxuan Liu; Xiangtian Li; Zhitao Zhou; Yunbing Chang; Jun Ouyang; Jingxing Dai

doi:10.1016/j.gendis.2024.101380

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Rapid Communication | Open Access

Actin polymerization regulates the osteogenesis of hASCs by influencing α-tubulin expression and Eg5 activity

Tingyu Fan^{^a^,¹}, Wenqing Liu^{^a^,¹}, Rongmei Qu^{^a}, Jinhui Zhu^{^a}, Yulian Shi^{^a}, Jiaxuan Liu^{^a}, Xiangtian Li^{^a}, Zhitao Zhou^{^b}, Yunbing Chang^{^c}(), Jun Ouyang^{^a}(), Jingxing Dai^{^a}()

Guangdong Provincial Key Laboratory of Digital Medicine and Biomechanics & Guangdong Engineering Research Center for Translation of Medical 3D Printing Application & National Virtual & Reality Experimental Education Center for Medical Morphology (Southern Medical University) & National Key Discipline of Human Anatomy, School of Basic Medical Sciences, Southern Medical University, Guangzhou, Guangdong 510515, China

Central Laboratory, Southern Medical University, Guangzhou, Guangdong 510515, China

Department of Spine Surgery, Guangdong Provincial People’s Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, Guangdong 510515, China

¹ These authors contributed equally to this work.

Peer review under responsibility of Chongqing Medical University.

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References

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Genes & Diseases

Volume 12 Issue 2,
March 2025

Article number: 101380

DOI: 10.1016/j.gendis.2024.101380

Cite this article:

Fan T, Liu W, Qu R, et al. Actin polymerization regulates the osteogenesis of hASCs by influencing α-tubulin expression and Eg5 activity. Genes & Diseases, 2025, 12(2): 101380. https://doi.org/10.1016/j.gendis.2024.101380