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Original Article | Open Access

Publication characteristics and visualized analysis of research about liver sinusoidal endothelial cells

Shanshan Zhaoa,b( ), Lan Zhanga, Junzhe Zhaoc, Farah Tasnimd, Hanry Yub,e,f
Department of Pharmacy, Xuanwu Hospital of Capital Medical University, National Clinical Research Center for Geriatric Diseases, Beijing Engineering Research Center for Nerve System Drugs, Beijing Municipal Geriatric Medical Research Center, Beijing 100053, China
Department of Physiology, The Institute for Digital Medicine (WisDM), Yong Loo Lin School of Medicine, MD9-04-11, 2 Medical Drive, Singapore 117593, Singapore
Duke-NUS Medical School, 8 College Road, Singapore 169857, Singapore
Biomedical Sciences Industry Partnership Office (BMSIPO), A*STAR, 31 Biopolis Way, Singapore 138669, Singapore
CAMP, Singapore-MIT Alliance for Research and Technology, 1 CREATE Way, Level 4 Enterprise Wing, Singapore 138602, Singapore
Mechanobiology Institute, National University of Singapore, T-Lab, #05-01, 5A Engineering Drive 1, Singapore 117411, Singapore
Show Author Information

Abstract

Background and aims

Through visual analysis of related literature, the main research direction and hot spots of liver sinusoidal endothelial cells (LSECs) in recent 24 years were explored.

Methods

This study used bibliometric analysis with CiteSpace, VOSviewer, Biblioshiny and online analytic tool bibliometric.com to provide a quantitative analysis, hot spot mining, and commentary of articles published in the field of LSECs research. The relevant literature in the Web of Science Core Collection (WOSCC) was searched from 2000 to 2023. The publications with topics or titles or keywords containing LSECs were included into this study. The countries, organizations, journals, authors, and keywords of the publications were summarized and analyzed.

Results

This study included 3,747 publications from 14,132 authors belonging to 389 institutions in 61 countries/regions and published in 150 journals, with 156,309 citations. The United States contributed most (1,150) to the publications. The most productive institution was the University of Sydney. Hepatology accounts for the most output (293, 7.8%), European authors had a widespread cooperation. The most productive author was Adam DH with 68 papers. Immunological function of LSECs is research hot spot.

Conclusion

This study highlights key trends based on a large dataset of the most influential publications about LSECs research over a 24-year period. It provides important clues and ideas for researchers focusing in this area and facilitates future liver disease mechanism, understanding, and treatment.

Keywords

BibliometricsCiteSpaceVOSviewerLiver sinusoidal endothelial cells

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iLIVER
Volume 3 Issue 1,
March 2024
DOI: 10.1016/j.iliver.2023.11.002
Cite this article:
Zhao S, Zhang L, Zhao J, et al. Publication characteristics and visualized analysis of research about liver sinusoidal endothelial cells. iLIVER, 2024, 3(1). https://doi.org/10.1016/j.iliver.2023.11.002

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Received: 16 October 2023
Revised: 03 November 2023
Accepted: 09 November 2023
Published: 28 November 2023
© 2023 The Authors. Tsinghua University Press.

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
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