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Editorial | Open Access

Criticality of an identification standard for mesenchymal stromal cells in clinical investigations

Hongyun Huanga( )Hari Shanker SharmabPaul R. SanbergcLin ChendAli OtomeGustavo A. MovigliafAnna Sarnowskag
Cell Therapy Center, Beijing Hongtianji Neuroscience Academy, Beijing 100143, China
Experimental Central Nervous System Injury & Repair, Anesthesiology & Intensive Care Medicine, Department of Surgical Sciences, University Hospital, Uppsala University, Uppsala SE-75185, Sweden
Center of Excellence for Aging & Brain Repair, Department of Neurosurgery & Brain Repair, Morsani College of Medicine, University of South Florida, Tampa 33612, FL, USA
Department of Neurosurgery, Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing 100007, China
Department of Rehabilitation Medicine, Jordan University Hospital, Amman 11183, Jordan
Wake Forest Institute for Regenerative Medicine, Wake Forest University, Winston-Salem 27109, NC, USA
Translational Platform for Regenerative Medicine, Mossakowski Medical Institute, Polish Academy of Science, Warsaw 02-106, Poland
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References

1

Huang HY, Sharma HS, Chen L, et al. Neurorestoratology: new advances in clin-ical therapy. CNS Neurol Disord: Drug Targets. 2023;22(7):1031–1038. https://doi.org/10.2174/1871527321666220827093805.

2

Huang HY, Ramon-Cueto A, El Masri W, et al. Advances in Neurorestoratology-Current status and future developments. Int Rev Neurobiol. 2023;171:207–239. https://doi.org/10.1016/bs.irn.2023.04.003.

3

Huang HY, Sanberg PR, Moviglia GA, et al. Clinical results of neurorestorative cell therapies and therapeutic indications according to cellular bio-proprieties. Regen Ther. 2023;23:52–59. https://doi.org/10.1016/j.reth.2023.03.004.

4

Chen D, Huang HY, Saberi H, et al. Positive and negative cell therapy in ran-domized control trials for central nervous system diseases. Int Rev Neurobiol. 2023;171:241–254. https://doi.org/10.1016/bs.irn.2023.05.017.

5

Horwitz EM, le Blanc K, Dominici M, et al. Clarification of the nomenclature for MSC: the international society for cellular therapy position statement. Cyto-therapy. 2005;7(5):393–395. https://doi.org/10.1080/14653240500319234.

6

Kuroda Y, Kitada M, Wakao S, et al. Unique multipotent cells in adult human mesenchymal cell populations. Proc Natl Acad Sci U S A. 2010;107(19): 8639–8643. https://doi.org/10.1073/pnas.0911647107.

7

Lo Furno D, Mannino G, Giuffrida R, et al. Neural differentiation of human adipose-derived mesenchymal stem cells induced by glial cell conditioned me-dia. J Cell Physiol. 2018;233(10):7091–7100. https://doi.org/10.1002/jcp.26632.

8

Russo C, Mannino G, Patane M, et al. Ghrelin peptide improves glial condi-tioned medium effects on neuronal differentiation of human adipose mesen-chymal stem cells. Histochem Cell Biol. 2021;156(1):35–46. https://doi.org/10.1007/s00418-021-01980-3.

9

Shi JM, Yin M. Effect of Wnt/b-catenin signaling pathway in neural differentia-tion of human bone marrow mesenchymal stem cells. Chin J Reparative Reconstr Surg. 2023;37(10):1276–1283. https://doi.org/10.7507/1002-1892.202306017.

10

Jaiswal J, Dhayal M. Rapid neurogenic differentiation of human mesenchymal stem cells through electrochemical stimulation. Bioelectrochemistry. 2023;153:108468. https://doi.org/10.1016/j.bioelechem.2023.108468.

11

Thrivikraman G, Madras G, Basu B. Electrically driven intracellular and extra-cellular nanomanipulators evoke neurogenic/cardiomyogenic differentiation in human mesenchymal stem cells. Biomaterials. 2016;77:26–43. https://doi.org/10.1016/j.biomaterials.2015.10.078.

12

Wu H, Gordon JAR, Whitfield TW, et al. Chromatin dynamics regulate mesen-chymal stem cell lineage specification and differentiation to osteogenesis. Bio-chim Biophys Acta Gene Regul Mech. 2017;1860(4):438–449. https://doi.org/10.1016/j.bbagrm.2017.01.003.

13

Xie TQ, Huang QM, Huang QL, et al. Dysregulated lncRNAs regulate human um-bilical cord mesenchymal stem cell differentiation into insulin-producing cells by forming a regulatory network with mRNAs. Stem Cell Res Ther. 2024;15(1): 22. https://doi.org/10.1186/s13287-023-03572-5.

14

Dominici M, le Blanc K, Mueller I, et al. Minimal criteria for defining multipo-tent mesenchymal stromal cells. The International Society for Cellular Therapy position statement. Cytotherapy. 2006;8(4):315–317. https://doi.org/10.1080/14653240600855905.

15

Wakao S, Kuroda Y, Ogura F, et al. Regenerative effects of mesenchymal stem cells: contribution of muse cells, a novel pluripotent stem cell type that resides in mesenchymal cells. Cells. 2012;1(4):1045–1060. https://doi.org/10.3390/cells1041045.

16

Galipeau J, Krampera M, Barrett J, et al. International Society for Cellular Ther-apy perspective on immune functional assays for mesenchymal stromal cells as potency release criterion for advanced phase clinical trials. Cytotherapy. 2016;18(2):151–159. https://doi.org/10.1016/j.jcyt.2015.11.008.

17

Viswanathan S, Shi Y, Galipeau J, et al. Mesenchymal stem versus stromal cells: international Society for Cell & Gene Therapy (ISCT®) Mesenchymal Stromal Cell committee position statement on nomenclature. Cytotherapy. 2019;21(10):1019–1024. https://doi.org/10.1016/j.jcyt.2019.08.002.

18

Viswanathan S, Ciccocioppo R, Galipeau J, et al. Consensus international council for commonality in blood banking automation-international society for cell & gene therapy statement on standard nomenclature abbreviations for the tissue of origin of mesenchymal stromal cells. Cytotherapy. 2021;23(12):1060–1063. https://doi.org/10.1016/j.jcyt.2021.04.009.

19

Ueda K, Sato Y, Shimizu S, et al. Systemic administration of clinical-grade mul-tilineage-differentiating stress-enduring cells ameliorates hypoxic-ischemic brain injury in neonatal rats. Sci Rep. 2023;13(1):14958. https://doi.org/10.1038/s41598-023-41026-3.

20

Xiang S, Gao W, Peng H, et al. Standards of clinical-grade mesenchymal stromal cell preparation and quality control (2020 China Version). J Neurorestoratol. 2020;8(4):197–216.

Journal of Neurorestoratology
Article number: 100115
Cite this article:
Huang H, Sharma HS, Sanberg PR, et al. Criticality of an identification standard for mesenchymal stromal cells in clinical investigations. Journal of Neurorestoratology, 2024, 12(2): 100115. https://doi.org/10.1016/j.jnrt.2024.100115

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Received: 23 February 2024
Published: 11 April 2024
© 2024 The Author(s).

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

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