AI Chat Paper
Note: Please note that the following content is generated by AMiner AI. SciOpen does not take any responsibility related to this content.
{{lang === 'zh_CN' ? '文章概述' : 'Summary'}}
{{lang === 'en_US' ? '中' : 'Eng'}}
Chat more with AI
Article Link
Collect
Submit Manuscript
Show Outline
Outline
Show full outline
Hide outline
Outline
Show full outline
Hide outline
Case Report | Open Access

Bilateral hypertrophic olivary degeneration caused by unilateral midbrain infarction: A case report

Yuying Suna,1Yunfei Zhanga,1Zhaoyang LuaZijie Chena,bJinggui Songb( )Ping Zhanga( )
Department of Neurology, The First Affiliated Hospital of Xinxiang Medical University, Xinxiang 453100, Henan, China
Department of Neurology, The Second Affiliated Hospital of Xinxiang Medical University (Henan Mental Hospital), Xinxiang 453000, Henan, China

1 These authors contributed equally to this work.

Show Author Information

Abstract

Hypertrophic olivary degeneration (HOD) arises from lesions of the dentato-rubro-olivary pathway (Guillain–Mollaret triangle), and bilateral HOD is the rarest. Our patient, a 42-year-old man with bilateral HOD caused by unilateral midbrain infarction, had both increased dizziness and ataxia as the first symptoms. HOD has no effective treatment and is easily misdiagnosed as other diseases in clinical practice. Our case demonstrated unique HOD symptomatology and emphasizes the important role of magnetic resonance imaging in diagnosing HOD. The use of gabapentin relieved nystagmus in our patient and may provide a reference for the future treatment of such patients.

References

1

Ogut E, Armagan K, Tufekci D. The Guillain-Mollaret triangle: a key player in motor coordination and control with implications for neurological disorders. Neurosurg Rev. 2023;46(1):181. https://doi.org/10.1007/s10143-023-02086-1.

2

Beez T, Munoz-Bendix C, Mijderwijk HJ, et al. Structural damage burden and hypertrophic olivary degeneration in pediatric postoperative cerebellar mutism syndrome. Neurosurg Rev. 2022;45(4):2757–2765. https://doi.org/10.1007/s10143-022-01791-7.

3

Assenza F, Genovese M, Cabboi MP, et al. Peribuccal and pharyngeal myorhythmia as a presenting symptom of hypertrophic olivary degeneration. Parkinsonism Relat Disord. 2021;85:141–143. https://doi.org/10.1016/j.parkreldis.2021.02.019.

4

Schaller-Paule MA, Steidl E, Shrestha M, et al. Multicenter Prospective Analysis of Hypertrophic Olivary Degeneration Following Infratentorial Stroke (HOD-IS): Evaluation of Disease Epidemiology, Clinical Presentation, and MR-Imaging Aspects. Front Neurol. 2021;12:675123. https://doi.org/10.3389/fneur.2021.675123.

5

Memmedova F, Sisman C, Yazici EL, et al. Bilateral hypertrophic olivary degeneration: case report. Neurol Sci. 2021;42(4):1573–1575. https://doi.org/10.1007/s10072-020-04741-7.

6

Steidl E, Rauch M, Hattingen E, et al. Qualitative and quantitative detectability of hypertrophic olivary degeneration in T2, FLAIR, PD, and DTI: A prospective MRI study. Front Neurol. 2022, 13: 950191. https://doi.org/10.3389/fneur.2022.950191.

7

Tilikete C, Desestret V. Hypertrophic Olivary Degeneration and Palatal or Oculopalatal Tremor. Front Neurol. 2017, 8: 302. https://doi.org/10.3389/fneur.2017.00302.

8

Raina GB, Cersosimo MG, Folgar SS, et al. Holmes tremor: Clinical description, lesion localization, and treatment in a series of 29 cases. Neurology. 2016;86(10):931–938. https://doi.org/10.1212/WNL.0000000000002440.

9

Van Eetvelde R, Lemmerling M, Backaert T, et al. Imaging Features of Hypertrophic Olivary Degeneration. J Belg Soc Radiol. 2016;100(1):71. https://doi.org/10.5334/jbr-btr.1065.

10

Konno T, Broderick DF, Tacik P, et al. Hypertrophic olivary degeneration: a clinico-radiologic study. Park Relat Disord. 2016;28:36–40. https://doi.org/10.1016/j.parkreldis.2016.04.008.

Journal of Neurorestoratology
Article number: 100141
Cite this article:
Sun Y, Zhang Y, Lu Z, et al. Bilateral hypertrophic olivary degeneration caused by unilateral midbrain infarction: A case report. Journal of Neurorestoratology, 2024, 12(4): 100141. https://doi.org/10.1016/j.jnrt.2024.100141

53

Views

0

Crossref

0

Web of Science

0

Scopus

Altmetrics

Received: 27 February 2024
Revised: 21 June 2024
Accepted: 08 July 2024
Published: 17 August 2024
© 2024 The Authors.

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

Return