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Original Article | Open Access

Analgesic effects and hemodynamic mechanisms of perpendicular and transverse needling at Sanyinjiao (SP 6) in patients with primary dysmenorrhea: A randomized controlled trial

Ali Mohammadia,b,1Mohammad Reza Afshari Farda,1Liangxiao Maa( )Jiedan MuaTianyi SunaWenyan YuaSanaz DehghanicMohammad Hossein Ayatid( )
School of Acupuncture-Moxibustion and Tuina, Beijing University of Chinese Medicine, Beijing, 102488, China
Faculty of Medicine, Shiraz Medical University of Iran, Shiraz, 7134814336, Iran
Qeshem International Branch, Islamic Azad University of Medical Science, Hormozgan, 7953163135, Iran
School of Traditional Medicine, Tehran University of Medical Sciences, Tehran, 1484754363, Iran

Peer review under responsibility of Beijing University of Chinese Medicine.

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Abstract

Objective

To explore the analgesic effects and uterine hemodynamics of perpendicular needling (PN) and transverse needling (TN) at SP 6 in patients with primary dysmenorrhea (PD).

Methods

In this randomized controlled trial, patients with PD diagnosed with cold-dampness congealing pattern were randomly assigned in a ratio of 1:1 to receive PN or TN at bilateral SP 6 for 10 min. Acupuncture was performed when the menstrual pain score was over 40 mm on the first day of menstruation, as measured using the visual analog scale for pain (VAS-P). The primary outcome was average menstrual pain (VAS-P). Secondary outcomes included the pulsatility index (PI), resistance index (RI), and systolic-diastolic peaks ratio (S/D) in uterine arteries as measured using color Doppler ultrasonography; anxiety as assessed using the Hamilton Anxiety Rating Scale (HAMA), blood pressure (BP), and heart rate (HR).

Results

Forty-eight patients completed the study. The TN group exhibited a significant reduction in VAS-P scores (–5.71 mm, 95% confidence interval (CI): –8.78, –2.63, P = .001), RI values (–0.05, 95% CI: –0.09, –0.01, P = .015), and HAMA values (–2.50, 95% CI: –4.78, –0.22, P = .032) when compared with the PN group. No significant differences in PI, S/D, BP, or HR values were observed between the two groups (P > .05).

Conclusion

TN at SP 6 was superior to PN in alleviating menstrual pain and anxiety in patients with PD. This analgesic effect of TN may be due to its better ability to improve uterine arterial blood flow via decreases in RI values.

Journal of Traditional Chinese Medical Sciences
Pages 248-256
Cite this article:
Mohammadi A, Afshari Fard MR, Ma L, et al. Analgesic effects and hemodynamic mechanisms of perpendicular and transverse needling at Sanyinjiao (SP 6) in patients with primary dysmenorrhea: A randomized controlled trial. Journal of Traditional Chinese Medical Sciences, 2021, 8(3): 248-256. https://doi.org/10.1016/j.jtcms.2021.07.002

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Received: 28 May 2021
Revised: 05 July 2021
Accepted: 07 July 2021
Published: 09 July 2021
© 2021 Beijing University of Chinese Medicine.

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

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