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Six saprobic fungal isolates were assayed for the in vitro antimicrobial activity against nine pathogenic microorganisms. The results showed that four fungal isolates including Clonostachys rosea MFLU10-0261, Fusicoccum aesculi MFLU10-0260, MFLU10-0266, and Ophioceras cf. leptosporum MFLU10-0281 were effective inhibitors against some test microorganisms. Of these, Ophioceras cf. leptosporum MFLU 10-0281 and Fusicoccum aesculi MFLU10-0260 exhibited a maximum inhibition zone of 15 ± 1 mm and 11 ± 1.6 mm against Staphylococcus aureus TISTR 1466 and Candida albicans TISTR 5779, respectively. These fungi also act as strong decomposers on leaves of Magnolia liliifera during the decay process from previous study. The results suggest that saprobic fungi could be a promising resource of useful bioactive compounds.
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