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Review | Open Access

Plants and endophytes – a partnership for the coumarin production through the microbial systems

Chandrashekar Srinivasaa, Govindappa Mellappab, Shashank M. Patilc, Ramith Ramuc, Bhargav Shreevatsac, Chandan Dharmashekarc, Shiva Prasad Kollurd,e, Asad Syedf, Chandan Shivamalluc( )
Department of Studies in Biotechnology, Davangere University, Davangere, India
Department of Studies in Botany, Davangere University, Davangere, India
Department of Biotechnology and Bioinformatics, School of Life Sciences, JSS Academy of Higher Education and Research, Mysuru, India
Department of Sciences, Amrita School of Arts and Sciences, Amrita Vishwa Vidyapeetham, Mysuru Campus, Mysuru, India
School of Agriculture, Geography, Environment, Ocean and Natural Sciences (SAGEONS), The University of South Pacific, Suva, Fiji
Department of Botany and Microbiology, College of Science, King Saud University, Riyadh, Saudi Arabia
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Abstract

Plant-based secondary metabolite production system is well established. However, host–endophyte interaction in the production of secondary metabolite is a new less exploited area that is overcoming barriers and evolving as one of the prospective fields. Endophytes such as bacteria or fungi have the ability to produce some of the secondary metabolites that mimic the plant metabolites therefore escaping the host defence system. Coumarin is one such metabolite with immense biological functions. Most of the studies have demonstrated coumarin production from fungal endophytes but not bacterial endophytes. Herein, we present an overview of all the coumarin derivatives produced from endophytic sources and their biosynthetic pathways. Furthermore, the review also throws light on the isolation of these coumarins and different derivatives with respect to their biological activity. The biotransformation of coumarin derivatives by the action of endophytic fungi is also elaborated. The present review provides an insight on the challenges faced in the coumarin production through fungal endophytes.

Keywords

Endophytic fungicoumarinhost–endophyte interactionsecondary metabolites

References

 

Bacon CW, Porter JK, Robbins JD, Luttrell ES. 1977. Epichloetyphina from toxic tall fescue grasses. Appl Environ Microbiol. 34(5):576–581. doi: 10.1128/aem.34.5.576-581.1977.
Crossref Google Scholar
 

Borges WDS, Borges KB, Bonato PS, Said S, Pupo MT. 2009. Endophytic fungi: natural products, enzymes and biotransformation reactions. Curr Org Chem. 13(12):1137–1163. doi: 10.2174/138527209788921783.
Crossref Google Scholar
 

Brader G, Compant S, Mitter B, Trognitz F, Sessitsch A. 2014. Metabolic potential of endophytic bacteria. Current Opinion in Biotechnology. 27: 30–37. doi: 10.1016/j.copbio.2013.09.012.
Crossref Google Scholar
 

Costa TM, Tavares LBB, de Oliveira D. 2016. Fungi as a source of natural coumarins production. Appl Microbiol Biotechnol. 100(15):6571–6584. doi: 10.1007/s00253-016-7660-z.
Crossref Google Scholar
 
de Bary A. 1866. Morphologie und Physiologie der Pilze, Flechten, und Myxomyceten. In: de Bary, A editors. Hofmeister’s handbook of physiological botany. Vol. Ⅱ. Leipzig (Germany): Engelmann.
Crossref
 

Debbab A, Aly AH, Proksch P. 2013. Mangrove derived fungal endophytes – a chemical and biological perception. Fungal Divers. 61:1–27. doi:10.1007/s13225-013-0243-8.
Crossref Google Scholar
 

Gagana SL, Kumaraswamy BE, Shivanna MB. 2020. Diversity, antibacterial and antioxidant activities of the fungal endophytes associated with Schleichera oleosa (Lour.) Merr. S Afr J Bot. 134:369–381. doi:10.1016/j.sajb.2020.06.012.
Crossref Google Scholar
 

Guerin P. 1898. Sur la presence d’un champignon dansl’ivraie. J Botanique. 12(1898):230–238.
Google Scholar
 

Han Z, Mei W, Zhao Y, Deng Y, Dai H. 2009. A new cytotoxic isocoumarin from endophytic fungus Penicillium sp. 091402 of the mangrove plant Bruguiera sexangula. Chem Nat Compd. 45(6):805–807. doi:10.1007/s10600-010-9503-y.
Crossref Google Scholar
 

Hansen GH, Lübeck M, Frisvad JC, Lübeck PS, Andersen B. 2015. Production of cellulolytic enzymes from ascomycetes: comparison of solid state and submerged fermentation. Process Biochem. 50(9):1327–1341. doi:10.1016/j.procbio.2015.05.017.
Crossref Google Scholar
 

Islam MR, Omar M, PK MMU, Mia MR, Phytochemicals K. 2015. Ganoderma lucidum and Lentinula edodes accessible in Bangladesh. Am J Biol Life Sci. 3(2):31–35.
Google Scholar
 

Liu X, Dong M, Chen X, Jiang M, Lv X, Zhou J. 2008. Antimicrobial activity of an endophytic Xylaria sp. YX-28 and identification of its antimicrobial compound 7-amino-4-methylcoumarin. Appl Microbiol Biotechnol. 78(2):241–247. doi:10.1007/s00253-007-1305-1.
Crossref Google Scholar
 

Lv X, Ma B, Warren A, Gong J. 2013. Shifts in diversity and community structure of endophytic bacteria and archaea across root, stem and leaf tissues in the common reed, Phragmites australis, along a salinity gradient in a marine tidal wetland of northern China. Antonie Van Leeuwenhoek. 104(5):759–768. doi:10.1007/s10482-013-9984-3.
Crossref Google Scholar
 

Melappa G. 2020. Identification of Bioactive Coumarin (s) from Three Endophytic Fungal Species of Calophyllum tomentosum. Nat Prod J. 10(4):502–512. doi:10.2174/2210315509666190430145906.
Crossref Google Scholar
 

Mousa WK, Raizada MN. 2013. The diversity of anti-microbial secondary metabolites produced by fungal endophytes: an interdisciplinary perspective. Frontiers in Microbiology. 4:65. doi:10.3389/fmicb.2013.00065.
Crossref Google Scholar
 

Nicoletti R, Fiorentino A. 2015. Plant bioactive metabolites and drugs produced by endophytic fungi of Spermatophyta. Agriculture. 5(4):918–970. doi:10.3390/agriculture5040918.
Crossref Google Scholar
 

Parshikov IA, Woodling KA, Sutherland JB. 2015. Biotransformations of organic compounds mediated by cultures of Aspergillus Niger. Appl Microbiol Biotechnol. 99(17):6971–6986. doi:10.1007/s00253-015-6765-0.
Crossref Google Scholar
 

Qin W, Liu C, Jiang W, Xue Y, Wang G, Liu S. 2019. A coumarin analogue NFA from endophytic Aspergillus fumigatus improves drought resistance in rice as an antioxidant. BMC Microbiol. 19(1):1–11. doi:10.1186/s12866-019-1419-5.
Crossref Google Scholar
 

Salvatore MM, Andolfi A, Nicoletti R. 2020. The thin line between pathogenicity and endophytism: the case of Lasiodiplodiatheobromae. Agriculture. 10(10):488. doi:10.3390/agriculture10100488.
Crossref Google Scholar
 

Schardl CL, Leuchtmann A, Spiering MJ. 2004. Symbioses of grasses with seedborne fungal endophytes. Annual Review of Plant Biology. 55:315–340. doi:10.1146/annurev.arplant.55.031903.141735.
Crossref Google Scholar
 

Shaaban M, El-Metwally MM, Laatsch H. 2016. New bioactive metabolites from Penicillium purpurogenum MM. Zeitschrift Für Naturforschung B. 71(4):287–295. doi:10.1515/znb-2015-0185.
Crossref Google Scholar
 

Shirahatti PS, Ramu R, Lakkapa DB, Prasad MNN. 2015 Oct. In vitro inhibitory activity of medicinal plants against phomopsis azadirachtae, the incitant die back disease of neem. Int J Pharm Pharmaceut Sci.7(13):199–04.
Google Scholar
 

Srikantaramas S, Asano T, Sudo H, Yamazaki M, Saito K. 2007. Camptothecin: therapeutic potential and Biotechnology. Curr Pharm Biotechnol. 8:196–202. doi:10.2174/138920107781387447.
Crossref Google Scholar
 

Stierle A, Strobel G, Stierle D. 1993. Taxol and taxane production by Taxomyces andreanae, an endophytic fungus of Pacific yew. Science. 260:214–216. doi:10.1126/science.8097061.
Crossref Google Scholar
 
Sudharshana TN, Venkatesh HN, Nayana B, Manjunath K, and Mohana DC. Anti-microbial and anti-mycotoxigenic activities of endophytic Alternaria alternata isolated from Catharanthus roseus (L.) G. Don.: molecular characterisation and bioactive compound isolation. Mycology. 2019 Jan 2;10(1):40–8.
Crossref
 

Symeonidis T, Chamilos M, Hadjipavlou-Litina DJ, Kallitsakis M, Litinas KE. 2009. Synthesis of hydroxycoumarins and hydroxybenzo [f]-or [h] coumarins as lipid peroxidation inhibitors. Bioorg Med Chem Lett. 19(4):1139–1142. doi:10.1016/j.bmcl.2008.12.098.
Crossref Google Scholar
 

TabishRehman M, U Khan A. 2015. Understanding the interaction between human serum albumin and anti-bacterial/anti-cancer compounds. Curr Pharm Des. 21(14):1785–1799. doi:10.2174/1381612821666150304161201.
Crossref Google Scholar
 

Taechowisan T, Lu C, Shen Y, Lumyong S. 2007. Antitumor activity of 4-arylcoumarins from endophytic Streptomyces aureofaciens CMUAc130. J Cancer Res Ther. 3(2):86. doi:10.4103/0973-1482.34685.
Crossref Google Scholar
 

Tandon R, Ponnan P, Aggarwal N, Pathak R, Baghel AS, Gupta G, Bose M. 2011. Characterization of 7-amino-4-methylcoumarin as an effective antitubercular agent: structure–activity relationships. J Antimicrob Chemother. 66(11):2543–2555. doi:10.1093/jac/dkr355.
Crossref Google Scholar
 

Tian H, Li XP, Zhao J, Gao HW, Xu QM, Wang JW. 2021. Biotransformation of artemisinic acid to bioactive derivatives by endophytic Penicillium oxalicum B4 from Artemisia annua L. Phytochemistry. 185:112682. doi:10.1016/j.phytochem.2021.112682.
Crossref Google Scholar
 

Umashankar T, Govindappa M, Ramachandra YL. 2012. In vitro antioxidant and anti-HIV activity of endophytic coumarin from Crotalaria pallida Aiton. Planta Med. 78(5):P_102. doi:10.1055/s-0032-1307610.
Crossref Google Scholar
 
Valdez-Nuñez RA, Castro-Tuanama R, Castellano-Hinojosa A, Bedmar EJ, and Ríos-Ruiz WF. 2019. PGPR characterization of non-nodulating bacterial endophytes from root nodules of Vignaunguiculata (L.) Walp. In: Zúñiga-Dávila, D, González-Andrés, F, and Ormeño-Orrillo, E editors. Microbial probiotics for agricultural systems. Cham: Springer; p. 111–126.
Crossref
 

Wang Y, and Guo LD. A comparative study of endophytic fungi in needles, bark, and xylem of Pinus tabulaeformis. Botany. 2007 Oct; 85(10):911–7.
Crossref Google Scholar
 

Xu J, Kjer J, Sendker J, Wray V, Guan H, Edrada R, … Proksch P. 2009. Cytosporones, coumarins, and an alkaloid from the endophytic fungus Pestalotiopsis sp. isolated from the Chinese mangrove plant Rhizophora mucronata. Bioorg Med Chem. 17(20):7362–7367. doi:10.1016/j.bmc.2009.08.031.
Crossref Google Scholar
 

Yamazaki T, Tokiwa T. 2010. Isofraxidin, a coumarin component from Acanthopanax senticosus, inhibits matrix metalloproteinase-7 expression and cell invasion of human hepatoma cells. Biol Pharm Bull. 33(10):1716–1722. doi:10.1248/bpb.33.1716.
Crossref Google Scholar
Mycology
Volume 13 Issue 4,
December 2022
Pages 243-256
DOI: 10.1080/21501203.2022.2027537
Cite this article:
Srinivasa C, Mellappa G, Patil SM, et al. Plants and endophytes – a partnership for the coumarin production through the microbial systems. Mycology, 2022, 13(4): 243-256. https://doi.org/10.1080/21501203.2022.2027537

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Received: 17 November 2021
Accepted: 06 January 2022
Published: 07 February 2022
© 2022 The Author(s).

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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