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Topical Review | Open Access

Functional microfluidics: theory, microfabrication, and applications

Mingzhu Xie1Ziheng Zhan1Yinfeng Li1Junkai Zhao2,3Ce Zhang3( )Zhaolong Wang1 ( )Zuankai Wang4( )
Interdisciplinary Research Center of Low-carbon Technology and Equipment, College of Mechanical and Vehicle Engineering, Hunan University, Changsha 410082, People’s Republic of China
Energy Research Institute of Shandong Academy of Sciences, Qilu University of Technology (Shandong Academy of Sciences), Jinan 250014, People’s Republic of China
Qian Xuesen Laboratory of Space Technology, China Academy of Space Technology (CAST), Beijing 100094, People’s Republic of China
Department of Mechanical Engineering, Hong Kong Polytechnic University, Hong Kong Special Administrative Region of China 999077, People’s Republic of China
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Abstract

Microfluidic devices are composed of microchannels with a diameter ranging from ten to a few hundred micrometers. Thus, quite a small (10−9–10−18 l) amount of liquid can be manipulated by such a precise system. In the past three decades, significant progress in materials science, microfabrication, and various applications has boosted the development of promising functional microfluidic devices. In this review, the recent progress on novel microfluidic devices with various functions and applications is presented. First, the theory and numerical methods for studying the performance of microfluidic devices are briefly introduced. Then, materials and fabrication methods of functional microfluidic devices are summarized. Next, the recent significant advances in applications of microfluidic devices are highlighted, including heat sinks, clean water production, chemical reactions, sensors, biomedicine, capillaric circuits, wearable electronic devices, and microrobotics. Finally, perspectives on the challenges and future developments of functional microfluidic devices are presented. This review aims to inspire researchers from various fields—engineering, materials, chemistry, mathematics, physics, and more—to collaborate and drive forward the development and applications of functional microfluidic devices, specifically for achieving carbon neutrality.

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International Journal of Extreme Manufacturing
Article number: 032005
Cite this article:
Xie M, Zhan Z, Li Y, et al. Functional microfluidics: theory, microfabrication, and applications. International Journal of Extreme Manufacturing, 2024, 6(3): 032005. https://doi.org/10.1088/2631-7990/ad2c5f

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Received: 29 June 2023
Revised: 05 September 2023
Accepted: 22 February 2024
Published: 19 March 2024
© 2024 The Author(s).

Original content from this work may be used under the terms of the Creative Commons Attribution 4.0 licence. Any further distribution of this work must maintain attribution to the author(s) and the title of the work, journal citation and DOI.

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