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Short Communication | Open Access

Complete resection of cavernous malformations in the hypothalamus: A case report and review of the literature

Xingchao Wang1, Zhenmin Wang1, Zhixian Gao1( ), Pinan Liu1,2( )
Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing 100050, China
Department of Neural Reconstruction, Beijing Neurosurgery Institute, Capital Medical University, Beijing 100050, China
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Abstract

Objective:

Cavernous malformation (CM) originating from the hypothalamus is extremely rare and the deep location presents a challenge for its neurosurgical management. We report such a case to better understand its clinical features.

Methods and Results:

A 40-year-old male patient presented with impaired vision in the left eye. Magnetic resonance imaging (MRI) revealed a regularly shaped round lesion located in the suprasellar cistern, and a clinical diagnosis of hypothalamic CM was made. Complete microsurgical excision was performed via a right pterional craniotomy. The patient showed good recovery with no further visual acuity or field deficits postoperatively. No CM recurrence or rebleeding was seen on follow-up MRI scans performed over the course of two years.

Conclusions:

For patients with cavernous malformation in the hypothalamus, accurate preoperative diagnosis with complete surgical removal by an appropriate surgical approach can contribute to satisfactory outcomes.

Keywords

surgeryhypothalamuscavernous malformationdeep-location

References

[1]
Batra S, Lin D, Recinos PF, Zhang J, Rigamonti D. Cavernous malformations: Natural history, diagnosis and treatment. Nat Rev Neurol 2009, 5(12): 659–670.
Crossref Google Scholar
[2]
Hassler W, Zentner J, Wilhelm H. Cavernous angiomas of the anterior visual pathways. J Clin Neuroophthalmol 1989, 9(3): 160–164.
Google Scholar
[3]
Mizutani T, Goldberg HI, Kerson LA, Murtagh F. Cavernous hemangioma in the diencephalon. Arch Neurol 1981, 38(6): 379–382.
Crossref Google Scholar
[4]
Reyns N, Assaker R, Louis E, Lejeune JP. Intraventricular cavernomas: Three cases and review of the literature. Neurosurgery 1999, 44(3): 648–654.
Crossref Google Scholar
[5]
Samii M, Eghbal R, Carvalho GA, Matthies C. Surgical management of brainstem cavernomas. J Neurosurg 2001, 95(5): 825–832.
Crossref Google Scholar
[6]
Abou-Al-Shaar H, Bahatheq A, Takroni R, Al-Thubaiti I. Optic chiasmal cavernous angioma: A rare suprasellar vascular malformation. Surg Neurol Int 2016, 7(Suppl 18): S523–S526.
Crossref Google Scholar
[7]
Liu JK, Lu Y, Raslan AM, Gultekin SH, Delashaw JB Jr. Cavernous malformations of the optic pathway and hypothalamus: Analysis of 65 cases in the literature. Neurosurg Focus 2010, 29(3): E17.
Crossref Google Scholar
[8]
Mizoi K, Yoshimoto T, Suzuki J. Clinical analysis of ten cases with surgically treated brain stem cavernous angiomas. Tohoku J Exp Med 1992, 166(2): 259–267.
Crossref Google Scholar
[9]
Kurokawa Y, Abiko S, Ikeda N, Ideguchi M, Okamura T. Surgical strategy for cavernous angioma in hypothalamus. J Clin Neurosci 2001, 8 Suppl1: 106–108.
Crossref Google Scholar
[10]
Katayama Y, Tsubokawa T, Maeda T, Yamamoto T. Surgical management of cavernous malformations of the third ventricle. J Neurosurg 1994, 80(1): 64–72.
Crossref Google Scholar
[11]
Rheinboldt M, Blase J. Exophytic hypothalamic cavernous malformation mimicking an extra-axial suprasellar mass. Emerg Radiol 2011, 18(4): 363–367.
Crossref Google Scholar
[12]
Gross BA, Du R. Cerebral cavernous malformations: Natural history and clinical management. Expert Rev Neurother 2015, 15(7): 771–777.
Crossref Google Scholar
[13]
Simard JM, Garcia-Bengochea F, Ballinger WE Jr, Mickle JP, Quisling RG. Cavernous angioma: A review of 126 collected and 12 new clinical cases. Neurosurgery 1986, 18(2): 162–172.
Crossref Google Scholar
[14]
Hempelmann RG, Mater E, Schröder F, Schön R. Complete resection of a cavernous haemangioma of the optic nerve, the chiasm, and the optic tract. Acta Neurochir (Wien) 2007, 149(7): 699–703; discussion 703.
Crossref Google Scholar
[15]
Wang CH, Lin SM, Chen Y, Tseng SH. Multiple deep-seated cavernomas in the third ventricle, hypothalamus and thalamus. Acta Neurochir (Wien) 2003, 145(6): 505–508.
Crossref Google Scholar
[16]
Ogawa Y, Tominaga T. Sellar and parasellar tumor removal without discontinuing antithrombotic therapy. J Neurosurg 2015, 123(3): 794–798.
Crossref Google Scholar
[17]
Hasegawa H, Bitoh S, Koshino K, Obashi J, Kobayashi Y, Kobayashi M, Wakasugi C. Mixed cavernous angioma and glioma (angioglioma) in the hypothalamus—Case report. Neurol Med Chir (Tokyo) 1995, 35(4): 238–242.
Crossref Google Scholar
[18]
Robinson JR, Awad IA, Little JR. Natural history of the cavernous angioma. J Neurosurg 1991, 75(5): 709–714.
Crossref Google Scholar
[19]
Porter RW, Detwiler PW, Spetzler RF, Lawton MT, Baskin JJ, Derksen PT, Zabramski JM. Cavernous malformations of the brainstem: Experience with 100 patients. J Neurosurg 1999, 90(1): 50–58.
Crossref Google Scholar
[20]
Lehner M, Fellner FA, Wurm G. Cavernous haemangiomas of the anterior visual pathways. Short review on occasion of an exceptional case. Acta Neurochir (Wien) 2006, 148(5): 571–578.
Crossref Google Scholar
Brain Science Advances
Volume 2 Issue 3,
September 2016
Pages 199-202
DOI: 10.18679/CN11-6030_R.2016.028
Cite this article:
Wang X, Wang Z, Gao Z, et al. Complete resection of cavernous malformations in the hypothalamus: A case report and review of the literature. Brain Science Advances, 2016, 2(3): 199-202. https://doi.org/10.18679/CN11-6030_R.2016.028

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Received: 05 July 2016
Revised: 26 July 2016
Accepted: 21 August 2016
Published: 01 September 2016
© The authors 2016.

This article is published with open access at www.TNCjournal.com
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