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Letter to the Editor | Open Access

A preclinical evaluation and first-in-man case for transcatheter edge-to-edge mitral valve repair using PulveClip® transcatheter repair device

Gang-Jun ZONG^{¹^,^*}, Jie-Wen DENG^{²^,^*}, Ke-Yu CHEN^², Hua WANG^², Fei-Fei DONG^², Xing-Hua SHAN^², Jia-Feng WANG^³, Ni ZHU^², Fei LUO^², Peng-Fei DAI^², Zhi-Fu GUO^², Yong-Wen QIN^², Yuan BAI^²()

Department of Cardiology, The 904th Hospital of Joint Logistic Support Force of PLA, Jiangsu, China

Department of Cardiology, Shanghai Changhai Hospital, Navy Military Medical University, Shanghai, China

Department of Anesthesiology, Shanghai Changhai Hospital, Navy Military Medical University, Shanghai, China

^*The authors contributed equally to this manuscript

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Journal of Geriatric Cardiology

Volume 22 Issue 2,
February 2025

Pages 265-269

DOI: 10.26599/1671-5411.2025.02.007

Cite this article:

ZONG G-J, DENG J-W, CHEN K-Y, et al. A preclinical evaluation and first-in-man case for transcatheter edge-to-edge mitral valve repair using PulveClip® transcatheter repair device. Journal of Geriatric Cardiology, 2025, 22(2): 265-269. https://doi.org/10.26599/1671-5411.2025.02.007

Hemodynamic parameters	Baseline	Post-procedure	P-value
Data are presented as means ± SD.
Mitral valve area, cm²	3.72 ± 1.06	3.52 ± 1.21	0.112
Left ventricular ejection fraction, %	63.14 ± 4.23	62.14 ± 1.53	0.09
Mean left atrium pressure, mmHg	11.8 ± 2.0	12.1 ± 1.5	0.231
Maximum transvalvular gradient, mmHg	1.3 ± 0.3	1.5 ± 1.0	0.441
Mean transvalvular gradient, mmHg	0.8 ± 0.4	0.71 ± 0.4	0.114
Left atrial anterior-posterior diameter, mm	29.8 ± 3.6	30.9 ± 2.6	0.009