References
Sato, T., Vries, R. G., Snippert, H. J., van de Wetering, M., Barker, N., Stange, D. E., van Es, J. H., Abo, A., Kujala, P., Peters, P. J. et al. Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche. Nature, 2009, 459(7244): 262–265. https://doi.org/10.1038/nature07935
Xiang, D. X., He, A. N., Zhou, R., Wang, Y. G., Xiao, X. Y., Gong, T., Kang, W. Y., Lin, X. L., Wang, X. C., PDO-based DST Consortium, et al. Building consensus on the application of organoid-based drug sensitivity testing in cancer precision medicine and drug development. Theranostics, 2024, 14(8): 3300–3316. https://doi.org/10.7150/thno.96027
Turajlic, S., Sottoriva, A., Graham, T., Swanton, C. Resolving genetic heterogeneity in cancer. Nature Reviews Genetics, 2019, 20(7): 404–416. https://doi.org/10.1038/s41576-019-0114-6
Zhao, Z. X., Chen, X. Y., Dowbaj, A. M., Sljukic, A., Bratlie, K., Lin, L. D., Fong, E. L. S., Balachander, G. M., Chen, Z. W., Soragni, A., et al. Organoids. Nature Reviews Methods Primers, 2022, 2: 94. https://doi.org/10.1038/s43586-022-00174-y
Hartung, T., Morales Pantoja, I. E., Smirnova, L. Brain organoids and organoid intelligence from ethical, legal, and social points of view. Frontiers in Artificial Intelligence, 2024, 6: 1307613. https://doi.org/10.3389/frai.2023.1307613
Shi, H. Y., Kowalczewski, A., Vu, D., Liu, X. Y., Salekin, A., Yang, H. X., Ma, Z. Organoid intelligence: Integration of organoid technology and artificial intelligence in the new era of in vitro models. Medicine in Novel Technology and Devices, 2024, 21: 100276. https://doi.org/10.1016/j.medntd.2023.100276
Milford, S. R., Shaw, D., Starke, G. Playing brains: The ethical challenges posed by silicon sentience and hybrid intelligence in DishBrain. Science and Engineering Ethics, 2023, 29(6): 38. https://doi.org/10.1007/s11948-023-00457-x
Han, X. X., Cai, C. H., Deng, W., Shi, Y. H., Li, L. Y., Wang, C., Zhang, J., Rong, M. J., Liu, J. P., Fang, B. J. et al. Landscape of human organoids: Ideal model in clinics and research. The Innovation, 2024, 5(3): 100620. https://doi.org/10.1016/j.xinn.2024.100620
Kataoka, M., Gyngell, C., Savulescu, J., Sawai, T. The ethics of human brain organoid transplantation in animals. Neuroethics, 2023, 16(3): 27. https://doi.org/10.1007/s12152-023-09532-3