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Research Article | Open Access

Immune-boosting effects of nutritional formulations containing acerola cherries extractive and lactoferrin

Haifu Jia1,§, Yuhong Wang1,§, Yueming Zhao2,3, Ziyu Hu1, Qingjing Liu2,3, Yanmei Hou2,3, Yujun Jiang1, Qianyu Zhao1( ), Chaoxin Man1( )
Key Laboratory of Dairy Science, Ministry of Education, College of Food Science, Northeast Agricultural University, Harbin 150030, China
Ausnutria Dairy (China) Co., Ltd., Changsha 410000, China
Aunulife Biotechnology Co., Ltd., Changsha 410000, China

§These authors contributed equally to this work.

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Abstract

Reduced immunity can harm the health of the organism, and nowadays, improving immunity is getting more and more attention, so the nutrients with immune boosting function (acerola cherry, taurine, zinc gluconate, and lactoferrin) are compounded in the best ratio to develop a nutritional formula food, and evaluated by cellular immunity, humoral immunity, non-specific immunity. In this study, an immunocompromised mice model was established using cyclophosphamide (CTX), the ability and difference of different components to enhance the immunity of mice were determined by the gavage of different components. The results showed that the nutritional formula food could recover the body weight of immunocompromised mice, promote the development of immune organs in immunocompromised mice, enhance the delayed-type hypersensitivity (DTH) response, the ability to produce serum hemolysin and the phagocytosis of monocytes in immunocompromised mice, and increase the levels of immunoglobulin A (IgA), IgG and IgM in the serum of immunocompromised mice. It has proved that this nutritional formula food (containing acerola cherry, taurine, zinc gluconate, and lactoferrin) has synergistic effect and can work together on humoral immunity, cellular immunity and non-specific immunity to improve the immune resistance of mice, and has promising application.

Keywords

acerola cherrylactoferrinnutrition formulationimmunity

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Food Science of Animal Products
Volume 2 Issue 1,
March 2024
Article number: 9240055
DOI: 10.26599/FSAP.2024.9240055
Cite this article:
Jia H, Wang Y, Zhao Y, et al. Immune-boosting effects of nutritional formulations containing acerola cherries extractive and lactoferrin. Food Science of Animal Products, 2024, 2(1): 9240055. https://doi.org/10.26599/FSAP.2024.9240055

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Received: 20 April 2024
Revised: 28 April 2024
Accepted: 06 May 2024
Published: 30 May 2024
© Beijing Academy of Food Sciences 2024.

Food Science of Animal Products published by Tsinghua University Press. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
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