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Review Article | Open Access

The Golgi apparatus in neurorestoration

Jianyang Liu, Jialin He, Yan Huang, Han Xiao, Zheng Jiang, Zhiping Hu( )
Department of Neurology, The Second Xiangya Hospital of Central South University, Changsha 410011, Hunan, China
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Abstract

The central role of the Golgi apparatus in critical cellular processes such as the transport, processing, and sorting of proteins and lipids has placed it at the forefront of cell science. Golgi apparatus dysfunction caused by primary defects within the Golgi or pharmacological and oxidative stress has been implicated in a wide range of neurodegenerative diseases. In addition to participating in disease progression, the Golgi apparatus plays pivotal roles in angiogenesis, neurogenesis, and synaptogenesis, thereby promoting neurological recovery. In this review, we focus on the functions of the Golgi apparatus and its mediated events during neurorestoration.

Keywords

Golgi apparatusneurogenesissynaptogenesisangiogenesisneurodegeneration

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Journal of Neurorestoratology
Volume 7 Issue 3,
September 2019
Pages 116-128
DOI: 10.26599/JNR.2019.9040017
Cite this article:
Liu J, He J, Huang Y, et al. The Golgi apparatus in neurorestoration. Journal of Neurorestoratology, 2019, 7(3): 116-128. https://doi.org/10.26599/JNR.2019.9040017

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Received: 16 July 2019
Revised: 08 September 2019
Accepted: 19 September 2019
Published: 09 October 2019
© The authors 2019

This article is published with open access at http://jnr.tsinghuajournals.com
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