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Review | Open Access

Advances and Prospects in Integrated Nano-oncology

Jinlei Jiang1,4Xinyuan Cui2Yixin Huang1,4Dongmei Yan3Bensong Wang1Ziyang Yang1,4Mingrui Chen1Junhao Wang1Yuna Zhang1Guan Liu1Cheng Zhou1,4Shengsheng Cui1,4Jian Ni1,4Fuhua Yang2( )Daxiang Cui1,4,5( )
Institute of Nano Biomedicine and Engineering, School of Sensing Science and Engineering, Shanghai Jiao Tong University, Shanghai 200240, China
Department of Radiology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China
Lianyungang Maternal and Child Health Hospital, Lianyungang 222000, China
National Engineering Research Center for Nanotechnology, Shanghai 200241, China
School of Medicine, Henan University, Kaifeng 475004, China
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Abstract

In recent years, the deep integration of basic research and clinical translational research of nanotechnology and oncology has led to the emergence of a new branch, namely integrated nano-oncology. This is an emerging and important interdisciplinary field, which plays an irreplaceable role in the diagnosis, treatment, early warning, monitoring and prevention of tumors, and has become a new interdisciplinary frontier. Here main advances of integrated nano-oncology was reviewed, mainly included controlled preparation of nanomaterials, ultra-sensitive detection of tumor biomarkers, multi-functional nanoimaging probes and integrated diagnosis and treatment technology, innovative nano drugs and nano drug delivery system, DNA nanotechnology, RNA nanotechnology, nano self-assembly technology, nanosensors, intelligent nanorobots, nanotherapeutic machines. The terms, concepts, trends and challenges are also discussed with the aim of promoting the application of nanotechnology in integrated oncology and solving the scientific and key technical problems in basic and clinical translational research of cancer.

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Nano Biomedicine and Engineering
Pages 152-187
Cite this article:
Jiang J, Cui X, Huang Y, et al. Advances and Prospects in Integrated Nano-oncology. Nano Biomedicine and Engineering, 2024, 16(2): 152-187. https://doi.org/10.26599/NBE.2024.9290060

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Received: 29 July 2023
Revised: 30 October 2023
Accepted: 24 November 2023
Published: 05 February 2024
© The Author(s) 2024.

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