Journal Home > Online First
Nano Biomedicine and Engineering https://doi.org/10.26599/NBE.2024.9290070
Review | Open Access | Online first | Published: 26 March 2024

Azadirachta indica-based Green Fabrication of Metal Oxide Nanoparticles: A State-of-the-Art Review

Show Author's Information Zille Huma1,§,  Musfira Arain2,§,  Muhammad Hammad Parvaiz1,  Sana Ullah3,  Khan Gul4,  Roohul Amin5,  Waheed Rehman2,  Faiq Saeed6( ),  Samia Arain7( )
Department of Chemistry, Riphah International University, Faisalabad 38000, Pakistan
School of Environmental Science and Engineering, Tianjin University, Tianjin 300072, China
Key Laboratory for Green Chemical Technology of the Ministry of Education, School of Chemical Engineering and Technology, Tianjin University, Tianjin 300072, China
Department of chemistry, Bacha Khan University Palosa, Charsadda, Pakistan
Government College Peshawar, University of Peshawar, Pakistan
Tianjin Key Laboratory of Low Dimensional Materials Physics and Preparing Technology, School of Science, Tianjin University, Tianjin 300072, China
Tianjin Key Laboratory of Molecular Optoelectronic Science, Department of Chemistry, School of Science, Tianjin University, Tianjin 300072, China

§These authors contributed equally to this work.

Keywords:
imaging, purification, microorganisms, metal oxide nanoparticles (NPs)
Cite this article:
Huma Z, Arain M, Parvaiz MH, et al. Azadirachta indica-based Green Fabrication of Metal Oxide Nanoparticles: A State-of-the-Art Review. Nano Biomedicine and Engineering, 2024, https://doi.org/10.26599/NBE.2024.9290070
Download citation
EndNote(RIS)
BibTeX

255

Views

47

Downloads

Citations

0

Crossref

N/A

WoS

0

Scopus

N/A

CSCD

Abstract Full text About this article

The green synthesis of metal oxide nanoparticles (MONPs) using Azadirachta indica (neem) as a biogenic reducing and capping agent is discussed in this review. Neem eliminates the need for harmful chemicals and solvents that are typically used in standard synthesis procedures of MONPs. This review discusses the many ways, such as coprecipitation, hydrothermal, and microemulsion approaches, that neem leaf extract can be used to produce oxide NPs. This review focused on obtaining data from recent advances in synthesis, characterization and applications of biological synthesis techniques. The relative abundance of A. indica (neem) means this can be widely used for creating reductant and stabilizing agents needed for MONPs formation. Using plant biomolecules in MONPs increases their toxicity toward microorganisms, enabling them to resist degradation and prevent ecological pollution. The review explores the size, shape, and crystal structure of neem-based NPs, which have potential uses in areas including water purification, biological imaging, and catalysis. Overall, this review finds that A. indica is a promising substitute for conventional synthetic techniques in the green synthesis of metallic oxide NPs.


menu
Abstract
Full text
Outline
About this article

Azadirachta indica-based Green Fabrication of Metal Oxide Nanoparticles: A State-of-the-Art Review

Show Author's information Zille Huma1,§, Musfira Arain2,§, Muhammad Hammad Parvaiz1, Sana Ullah3, Khan Gul4, Roohul Amin5, Waheed Rehman2, Faiq Saeed6( ), Samia Arain7( )
Department of Chemistry, Riphah International University, Faisalabad 38000, Pakistan
School of Environmental Science and Engineering, Tianjin University, Tianjin 300072, China
Key Laboratory for Green Chemical Technology of the Ministry of Education, School of Chemical Engineering and Technology, Tianjin University, Tianjin 300072, China
Department of chemistry, Bacha Khan University Palosa, Charsadda, Pakistan
Government College Peshawar, University of Peshawar, Pakistan
Tianjin Key Laboratory of Low Dimensional Materials Physics and Preparing Technology, School of Science, Tianjin University, Tianjin 300072, China
Tianjin Key Laboratory of Molecular Optoelectronic Science, Department of Chemistry, School of Science, Tianjin University, Tianjin 300072, China

§These authors contributed equally to this work.

Abstract

The green synthesis of metal oxide nanoparticles (MONPs) using Azadirachta indica (neem) as a biogenic reducing and capping agent is discussed in this review. Neem eliminates the need for harmful chemicals and solvents that are typically used in standard synthesis procedures of MONPs. This review discusses the many ways, such as coprecipitation, hydrothermal, and microemulsion approaches, that neem leaf extract can be used to produce oxide NPs. This review focused on obtaining data from recent advances in synthesis, characterization and applications of biological synthesis techniques. The relative abundance of A. indica (neem) means this can be widely used for creating reductant and stabilizing agents needed for MONPs formation. Using plant biomolecules in MONPs increases their toxicity toward microorganisms, enabling them to resist degradation and prevent ecological pollution. The review explores the size, shape, and crystal structure of neem-based NPs, which have potential uses in areas including water purification, biological imaging, and catalysis. Overall, this review finds that A. indica is a promising substitute for conventional synthetic techniques in the green synthesis of metallic oxide NPs.

Keywords: imaging, purification, microorganisms, metal oxide nanoparticles (NPs)

References(112)

[1]

S. Adewale Akintelu, A. Kolawole Oyebamiji, Charles S. Olugbeko, et al. Green chemistry approach towards the synthesis of copper nanoparticles and its potential applications as therapeutic agents and environmental control. Current Research in Green and Sustainable Chemistry, 2021, 4: 100176. https://doi.org/10.1016/j.crgsc.2021.100176
DOI Google Scholar
[2]

M. Nasrollahzadeh, M. Sajjadi, J. Dadashi, et al. Pd-based nanoparticles: Plant-assisted biosynthesis, characterization, mechanism, stability, catalytic and antimicrobial activities. Advances in Colloid and Interface Science, 2020, 276: 102103. https://doi.org/10.1016/j.cis.2020.102103
DOI Google Scholar
[3]

S. Sathiyavimal, S. Vasantharaj, V. Veeramani, et al. Green chemistry route of biosynthesized copper oxide nanoparticles using Psidium guajava leaf extract and their antibacterial activity and effective removal of industrial dyes. Journal of Environmental Chemical Engineering, 2021, 9(2): 105033. https://doi.org/10.1016/j.jece.2021.105033
DOI Google Scholar
[4]

D. Nawal, P.R.S. Deora, C.G. Priya. A short review on green synthesis of iron oxide npsby neem plant (Azadirachta Indica) leavs extract. International Journal of Mechanical Engineering, 2022, 7(4): 1555−1562.
Google Scholar
[5]

M.S. Chavali, M.P. Nikolova. Metal oxide nanoparticles and their applications in nanotechnology. SN Applied Sciences, 2019, 1(6): 607. https://doi.org/10.1007/s42452-019-0592-3
DOI Google Scholar
[6]

S.A. Akintelu, A.S. Folorunso, O.T. Ademosun. Instrumental characterization and antibacterial investigation of silver nanoparticles synthesized from garcinia kola leaf. Journal of Drug Delivery and Therapeutics, 2019, 9(6-s): 58−64. https://doi.org/10.22270/jddt.v9i6-s.3749
DOI Google Scholar
[7]
A.S. Adewale, F.A. Similoluwa. Biosynthesis, characterization and antifungal investigation of Ag-Cu NPs from rind extracts of Garcina kola. Stem Cell, 2019, 10(4): 30–37.
[8]

A. Folorunso, S. Akintelu, A.K. Oyebamiji, et al. Biosynthesis, characterization and antimicrobial activity of gold nanoparticles from leaf extracts of Annona muricata. Journal of Nanostructure in Chemistry, 2019, 9(2): 111−117. https://doi.org/10.1007/s40097-019-0301-1
DOI Google Scholar
[9]

F.F.M. Al-Kazazz, S.H. Jaber, A.H. Mohammed, et al. Preparation of magnesium oxide nanoparticles and study its loaded with recombinant human erythropoietin Alfa drug. Nano Biomedicine and Engineering, 2022, 14(2): 186−191. https://doi.org/10.5101/nbe.v14i2.p186-191
DOI Google Scholar
[10]

S. Jadoun, R. Arif, N.K. Jangid, et al. Green synthesis of nanoparticles using plant extracts: A review. Environmental Chemistry Letters, 2021, 19(1): 355−374. https://doi.org/10.1007/s10311-020-01074-x
DOI Google Scholar
[11]

M. Nasrollahzadeh, N. Shafiei, Z. Nezafat, et al. Valorisation of fruits, their juices and residues into valuable (Nano)materials for applications in chemical catalysis and environment. The Chemical Record, 2020, 20(11): 1338−1393. https://doi.org/10.1002/tcr.202000078
DOI Google Scholar
[12]

S.K. Moorthy, C. Ashok, K.V. Rao, et al. Synthesis and characterization of mgo nanoparticles by neem leaves through green method. Materials Today:Proceedings, 2015, 2(9): 4360−4368. https://doi.org/10.1016/j.matpr.2015.10.027
DOI Google Scholar
[13]

S. Yasin, L. Liu, J. Yao. Biosynthesis of silver NPs by bamboo leavs extract and their antimicrobial activity. Journal of Fiber Bioengineering and Informatics, 2013, 6(6): 77−84. https://doi.org/10.3993/jfbi03201307
DOI Google Scholar
[14]

K.S. Kavitha, S. Baker, D. Rakshith, et al. Plants as green source towards synthesis of nanoparticles. International Research Journal of Biological Sciences, 2013, 2(6): 66−76.
Google Scholar
[15]

F.Y. Meng, H.X. Sun, Y. Huang, et al. Peptide cleavage-based electrochemical biosensor coupling graphene oxide and silver nanoparticles. Analytica Chimica Acta, 2019, 1047: 45−51. https://doi.org/10.1016/j.aca.2018.09.053
DOI Google Scholar
[16]

S. Kamble, K. Bhisale, M. Mohite, et al. Methods of preparation of nanoparticles. International Journal of Advances in Engineering &Technology, 2022, 2(1): 640−646.
DOI Google Scholar
[17]

R. Chandrasekaran, S. Gnanasekar, P. Seetharaman, et al. Formulation of Carica papaya latex-functionalized silver nanoparticles for its improved antibacterial and anticancer applications. Journal of Molecular Liquids, 2016, 219: 232−238. https://doi.org/10.1016/j.molliq.2016.03.038
DOI Google Scholar
[18]

Q.H. Tran, V.Q. Nguyen, A.-T. Le. Silver nanoparticles: synthesis, properties, toxicology, application and perspectives. Advances in Natural Sciences:Nanoscience and Nanotechnology, 2013, 4(3): 033001. https://doi.org/10.1088/2043-6262/4/3/033001
DOI Google Scholar
[19]

H. Abdul Salam, R. Sivaraj, R. Venckatesh. Green synthesis and characterization of zinc oxide nanoparticles from Ocimum basilicum L. var. purpurascens Benth.-Lamiaceae leaf extract. Materials Letters, 2014, 131: 16−18. https://doi.org/10.1016/j.matlet.2014.05.033
DOI Google Scholar
[20]

J.K. Sharma, P. Srivastava, S. Ameen, et al. Azadirachta indica plant-assisted green synthesis of Mn3O4 nanoparticles: Excellent thermal catalytic performance and chemical sensing behavior. Journal of Colloid and Interface Science, 2016, 472: 220−228. https://doi.org/10.1016/j.jcis.2016.03.052
DOI Google Scholar
[21]

G.K. Prashanth, G.M. Krishnaiah. Chemical composition of the leavs of Azadirachta indica Linn (Neem). International Journal of Advancement in Engineering and Technology,Management and Applied Science, 2014, 1(5): 21−31.
Google Scholar
[22]
S. Maji. Role of neem leavs in diabetes and obesity. In: Role of Phytochemicals in Human Physiological Disorders: Diabetes and Obesity.Scholars’ Press: Atlanta, 2020: 85–102.
[23]

P. Bharat, R. Sagar, R. Sulav, et al. Investigations of antioxidant and antibacterial activity of leaf extracts of Azadirachta indica. African Journal of Biotechnology, 2015, 14(46): 3159−3163. https://doi.org/10.5897/ajb2015.14811
DOI Google Scholar
[24]

M.A. Hossain, W.A.S. Al-Toubi, A.M. Weli, et al. Identification and characterization of chemical compounds in different crude extracts from leaves of Omani neem. Journal of Taibah University for Science, 2013, 7(4): 181−188. https://doi.org/10.1016/j.jtusci.2013.05.003
DOI Google Scholar
[25]

S. Siddiqui, S. Faizi, B.S. Siddiqui, et al. Constituents of azadirachta indica: Isolation and structure elucidation of a new antibacterial tetranortriterpenoid, mahmoodin, and a new protolimonoid, naheedin. Journal of Natural Products, 1992, 55(3): 303−310. https://doi.org/10.1021/np50081a005
DOI Google Scholar
[26]

S. Banerjee, T. Ghosh, S. Barik, et al. Neem leaf glycoprotein prophylaxis transduces immune dependent stop signal for tumor angiogenic switch within tumor microenvironment. PLoS One, 2014, 9(11): e110040. https://doi.org/10.1371/journal.pone.0110040
DOI Google Scholar
[27]

N.K. Chundran, I.R. Husen, I. Rubianti. Effect of neem leaves extract (Azadirachta indica) on wound healing. Althea Medical Journal, 2015, 2(2): 199−203. https://doi.org/10.15850/amj.v2n2.535
DOI Google Scholar
[28]

C. Sharma, A.J. Vas, P. Goala, et al. Ethanolic neem (Azadirachta indica) leaf extract prevents growth of MCF-7 and HeLa cells and potentiates the therapeutic index of cisplatin. Journal of Oncology, 2014, 2014: 321754. https://doi.org/10.1155/2014/321754
DOI Google Scholar
[29]

F.R. Durrani, N. Chand, M. Jan, et al. Immunomodulatory and growth promoting effects of neem leavs infusion in broiler chicks. Sarhad Journal of Agriculture, 2008, 24(4): 655−659.
Google Scholar
[30]

F.R. Durrani, N. Chand, S. Akhtar. Hematological, biochemical, immunomodulatory and growth promoting effect of feed added wild mint (Mentha longifolia) in broiler chicks. Sarhad Journal of Agriculture, 2008, 24(4): 661−665.
Google Scholar
[31]

P.A. Peer, P.C. Trivedi, P.B. Nigade, et al. Cardioprotective effect of Azadirachta indica A. Juss. on isoprenaline induced myocardial infarction in rats. International Journal of Cardiology, 2008, 126(1): 123−126. https://doi.org/10.1016/j.ijcard.2007.01.108
DOI Google Scholar
[32]

A.-V. Ferlemi, F. Lamari. Berry leaves: An alternative source of bioactive natural products of nutritional and medicinal value. Antioxidants, 2016, 5(2): 17. https://doi.org/10.3390/antiox5020017
DOI Google Scholar
[33]

N. Esther, T. Fatima, B. Agbo Ediga. Evaluation of phytochemicals and activity index of some plant leaf extracts on typhoidal and non-typhoidal Salmonella isolates from selected hospitals in Bauchi, Nigeria. GSC Biological and Pharmaceutical Sciences, 2020, 10(2): 120−129. https://doi.org/10.30574/gscbps.2020.10.2.0204
DOI Google Scholar
[34]

C. Okoli, P. Akah, A.S. Okoli. Potentials of leaves of Aspilia Africana (Compositae) in wound care: An experimental evaluation. BMC Complementary and Alternative Medicine, 2007, 7(1): 24. https://doi.org/10.1186/1472-6882-7-24
DOI Google Scholar
[35]

T. Revathi, S. Thambidurai. Cytotoxic, antioxidant and antibacterial activities of copper oxide incorporated chitosan-neem seed biocomposites. International Journal of Biological Macromolecules, 2019, 139: 867−878. https://doi.org/10.1016/j.ijbiomac.2019.07.214
DOI Google Scholar
[36]

B.Q. Jia, Y. Mei, L. Cheng, et al. Preparation of copper nanoparticles coated cellulose films with antibacterial properties through one-step reduction. ACS Applied Materials &Interfaces, 2012, 4(6): 2897−2902. https://doi.org/10.1021/am3007609
DOI Google Scholar
[37]

N. Nagar, V. Devra. Green synthesis and characterization of copper nanoparticles using Azadirachta indica leaves. Materials Chemistry and Physics, 2018, 213: 44−51. https://doi.org/10.1016/j.matchemphys.2018.04.007
DOI Google Scholar
[38]

A. Dey, S. Manna, S. Chattopadhyay, et al. Azadirachta indica leaves mediated green synthesized copper oxide nanoparticles induce apoptosis through activation of TNF-α and caspases signaling pathway against cancer cells. Journal of Saudi Chemical Society, 2019, 23(2): 222−238. https://doi.org/10.1016/j.jscs.2018.06.011
DOI Google Scholar
[39]

Z.Y. Duan, G.L. Ma, W.J. Zhang. Preparation of copper nanoparticles and catalytic properties for the reduction of aromatic nitro compounds. Bulletin of the Korean Chemical Society, 2012, 33(12): 4003−4006. https://doi.org/10.5012/bkcs.2012.33.12.4003
DOI Google Scholar
[40]

A.H. Wani, M.A. Shah. A unique and profound effect of MgO and ZnO NPson some plant pathogenic fungi. Journal of Applied Pharmaceutical Science, 2012, 2(3): 40−44.
Google Scholar
[41]

J. Sawai. Quantitative evaluation of antibacterial activities of metallic oxide powders (ZnO, MgO and CaO) by conductimetric assay. Journal of Microbiological Methods, 2003, 54(2): 177−182. https://doi.org/10.1016/s0167-7012(03)00037-x
DOI Google Scholar
[42]

J.K. Sharma, P. Srivastava, S. Singh, et al. Review on the catalytic effect of nanoparticles on the thermal decomposition of ammonium perchlorate. Energy and Environment Focus, 2014, 3(2): 121−130. https://doi.org/10.1166/eef.2014.1079
DOI Google Scholar
[43]

Z. Durmus, A. Baykal, H. Kavas, et al. Ovalbumin mediated synthesis of Mn3O4. Polyhedron, 2009, 28(11): 2119−2122. https://doi.org/10.1016/j.poly.2009.03.026
DOI Google Scholar
[44]

F. Davar, M. Salavati-Niasari, N. Mir, et al. Thermal decomposition route for synthesis of Mn3O4 nanoparticles in presence of a novel precursor. Polyhedron, 2010, 29(7): 1747−1753. https://doi.org/10.1016/j.poly.2010.02.026
DOI Google Scholar
[45]

R. Mehdizadeh, L. Ali Saghatforoush, S. Sanati. Solvothermal synthesis and characterization of α-Fe2O3 nanodiscs and Mn3O4 nanoparticles with 1, 10-phenanthroline. Superlattices and Microstructures, 2012, 52(1): 92−98. https://doi.org/10.1016/j.spmi.2012.03.017
DOI Google Scholar
[46]

J.K. Sharma, P. Srivastava, G. Singh, et al. Catalytic thermal decomposition of ammonium perchlorate and combustion of composite solid propellants over green synthesized CuO nanoparticles. Thermochimica Acta, 2015, 614: 110−115. https://doi.org/10.1016/j.tca.2015.06.023
DOI Google Scholar
[47]

M.H. Jameel, M.Z.H. Bin Mayzan, M.S. bin Roslan, et al. Experimental and theoretical DFT study of hydrothermally synthesized MoS2-doped-TiO2 nanocomposites for photocatalytic application. Journal of Photochemistry and Photobiology A:Chemistry, 2024, 448: 115334. https://doi.org/10.1016/j.jphotochem.2023.115334
DOI Google Scholar
[48]

J.K. Sharma, P. Srivastava, G. Singh. Nanocatalysts: Potential burning rate modifier for composite solid propellants. Materials Focus, 2014, 3(2): 81−91. https://doi.org/10.1166/mat.2014.1154
DOI Google Scholar
[49]

G. Singh, S.P. Felix. Studies of energetic compounds, part 29: Effect of NTO and its salts on the combustion and condensed phase thermolysis of composite solid propellants, HTPB-AP. Combustion and Flame, 2003, 132(3): 422−432. https://doi.org/10.1016/s0010-2180(02)00479-0
DOI Google Scholar
[50]

A.L. Neal. What can be inferred from bacterium–nanoparticle interactions about the potential consequences of environmental exposure to nanoparticles. Ecotoxicology, 2008, 17(5): 362−371. https://doi.org/10.1007/s10646-008-0217-x
DOI Google Scholar
[51]

A. van Dijken, E.A. Meulenkamp, D. Vanmaekelbergh, et al. Identification of the transition responsible for the visible emission in ZnO using quantum size effects. Journal of Luminescence, 2000, 90(3-4): 123−128. https://doi.org/10.1016/s0022-2313(99)00599-2
DOI Google Scholar
[52]

D. Kundu, C. Hazra, A. Chatterjee, et al. Extracellular biosynthesis of zinc oxide nanoparticles using Rhodococcus pyridinivorans NT2: Multifunctional textile finishing, biosafety evaluation and in vitro drug delivery in colon carcinoma. Journal of Photochemistry and Photobiology B:Biology, 2014, 140: 194−204. https://doi.org/10.1016/j.jphotobiol.2014.08.001
DOI Google Scholar
[53]

S. Saleem, M.H. Jameel, A. Rehman, et al. Evaluation of structural, morphological, optical, and electrical properties of zinc oxide semiconductor nanoparticles with microwave plasma treatment for electronic device applications. Journal of Materials Research and Technology, 2022, 19: 2126−2134. https://doi.org/10.1016/j.jmrt.2022.05.190
DOI Google Scholar
[54]

A. Kajbafvala, H. Ghorbani, A. Paravar, et al. Effects of morphology on photocatalytic performance of Zinc oxide nanostructures synthesized by rapid microwave irradiation methods. Superlattices and Microstructures, 2012, 51(4): 512−522. https://doi.org/10.1016/j.spmi.2012.01.015
DOI Google Scholar
[55]

K. Kairyte, A. Kadys, Z. Luksiene. Antibacterial and antifungal activity of photoactivated ZnO nanoparticles in suspension. Journal of Photochemistry and Photobiology B,Biology, 2013, 128: 78−84. https://doi.org/10.1016/j.jphotobiol.2013.07.017
DOI Google Scholar
[56]

G. Sangeetha, S. Rajeshwari, R. Venckatesh. Green synthesis of zinc oxide nanoparticles by aloe barbadensis miller leaf extract: Structure and optical properties. Materials Research Bulletin, 2011, 46(12): 2560−2566. https://doi.org/10.1016/j.materresbull.2011.07.046
DOI Google Scholar
[57]

C.N.R. Rao, S.R.C. Vivekchand, K. Biswas, et al. Synthesis of inorganic nanomaterials. Dalton Transactions, 2007(34): 3728−3749. https://doi.org/10.1039/B708342D
DOI Google Scholar
[58]

A. Kajbafvala, J.P. Samberg, H. Ghorbani, et al. Effects of initial precursor and microwave irradiation on step-by-step synthesis of zinc oxide nano-architectures. Materials Letters, 2012, 67(1): 342−345. https://doi.org/10.1016/j.matlet.2011.09.106
DOI Google Scholar
[59]
T.C. Prathna, L. Mathew, N. Chandrasekaran, et al. Biomimetic synthesis of nanoparticles: Science, technology & applicability. In: Biomimetics Learning from Nature. Mukherjee, A., ed. InTech, 2010.
DOI
[60]

S.S. Shankar, A. Ahmad, R. Pasricha, et al. Bioreduction of chloroaurate ions by geranium leaves and its endophytic fungus yields gold nanoparticles of different shapes. Journal of Materials Chemistry, 2003, 13(7): 1822. https://doi.org/10.1039/b303808b
DOI Google Scholar
[61]

J.K. Sharma, P. Srivastava, S. Ameen, et al. Phytoconstituents assisted green synthesis of cerium oxide nanoparticles for thermal decomposition and dye remediation. Materials Research Bulletin, 2017, 91: 98−107. https://doi.org/10.1016/j.materresbull.2017.03.034
DOI Google Scholar
[62]

G.A. Ashraf, R.T. Rasool, M.M. Fadhali, et al. Novel magnetic carbon@BaBiFe12O19 photocatlyst for efficient pollutants degradation under peroxymonosulphate activation. Materials Science in Semiconductor Processing, 2024, 176: 108291. https://doi.org/10.1016/j.mssp.2024.108291
DOI Google Scholar
[63]

M.H. Jameel, S. Ahmed, Z.Y. Jiang, et al. First principal calculations to investigate structural, electronic, optical, and magnetic properties of Fe3O4and Cd-doped Fe2O4. Computational Condensed Matter, 2022, 30: e00629. https://doi.org/10.1016/j.cocom.2021.e00629
DOI Google Scholar
[64]

N.D.S. Zambri, N.I. Taib, F. Abdul Latif, et al. Utilization of neem leaf extract on biosynthesis of iron oxide nanoparticles. Molecules, 2019, 24(20): 3803. https://doi.org/10.3390/molecules24203803
DOI Google Scholar
[65]

N.L. Mohammad Mohaidin, U.T. Mara, F. Aris, et al. Antibiofilm property of green synthesized iron oxide nanoparticles from neem leaves. Journal of Sustainability Science and Management, 2022, 17(3): 279−290. https://doi.org/10.46754/jssm.2022.03.021
DOI Google Scholar
[66]

F. Samia, Saeed, J. Li, M. Arain, et al. Emerging trends in metal-organic framework (MOFs) photocatalysts for hydrogen energy using water splitting: A state-of-the-art review. Journal of Industrial and Engineering Chemistry, 2024, 131: 54−135. https://doi.org/10.1016/j.jiec.2023.10.055
DOI Google Scholar
[67]
J.K. Sharma, P. Srivastava, M.S. Akhtar, et al. α-Fe2O3 hexagonal cones synthesized from the leaf extract of Azadirachta indica and its thermal catalytic activity. New Journal of Chemistry, 2015, 39(9): 7105–7111.
DOI
[68]

S. Saha, P. Samanta, N.C. Murmu, et al. A review on the heterostructure nanomaterials for supercapacitor application. Journal of Energy Storage, 2018, 17: 181−202. https://doi.org/10.1016/j.est.2018.03.006
DOI Google Scholar
[69]
A.K. Satpati. Synthesis strategies and applications of metallic foams and hollow structured materials. In: Handbook on Synthesis Strategies for Advanced Materials. Singapore: Springer, 2022: 325–376.
DOI
[70]

Y.F. Zhang, X.H. Liu, J.R. Nie, et al. Improve the catalytic activity of α-Fe2O3 particles in decomposition of ammonium perchlorate by coating amorphous carbon on their surface. Journal of Solid State Chemistry, 2011, 184(2): 387−390. https://doi.org/10.1016/j.jssc.2010.12.004
DOI Google Scholar
[71]

R.N. Kharwar, V.K. Sharma, A. Mishra, et al. Harnessing the phytotherapeutic treasure troves of the ancient medicinal plant azadirachta indica (neem) and associated endophytic microorganisms. Planta Medica, 2020, 86(13/14): 906−940. https://doi.org/10.1055/a-1107-9370
DOI Google Scholar
[72]

M.H. Lin, S.F. Yang, J.G. Huang, et al. Insecticidal triterpenes in Meliaceae: Plant species, molecules and activities: Part Ⅰ (Aphanamixis-Chukrasia). International Journal of Molecular Sciences, 2021, 22(24): 13262. https://doi.org/10.3390/ijms222413262
DOI Google Scholar
[73]

G. Chianese, S.R. Yerbanga, L. Lucantoni, et al. Antiplasmodial triterpenoids from the fruits of neem. Azadirachta indica. Journal of Natural Products, 2010, 73(8): 1448−1452. https://doi.org/10.1021/np100325q
DOI Google Scholar
[74]

D. Tristantini, W. Wahidin, F. Feliana, et al. Immunomodulatory and antioxidant activity from Indonesian anti-degenerative herbs water extract. Journal of Complementary and Integrative Medicine, 2021, 18(4): 695−700. https://doi.org/10.1515/jcim-2020-0223
DOI Google Scholar
[75]

K. Chojnacka, D. Skrzypczak, G. Izydorczyk, et al. Antiviral properties of polyphenols from plants. Foods, 2021, 10(10): 2277. https://doi.org/10.3390/foods10102277
DOI Google Scholar
[76]

A. Gupta, S. Ansari, S. Gupta, et al. Therapeutics role of neem and its bioactive constituents in disease prevention and treatment. Journal of Pharmacognosy and Phytochemistry, 2019, 8(3): 680−691.
Google Scholar
[77]

N. Narimatsu, M. Saito, E. Kazuyama, et al. N-hexacosanol prevents diabetes-induced rat ileal dysfunction without qualitative alteration of the muscarinic receptor system. Biomedical Research, 2007, 28(5): 267−273. https://doi.org/10.2220/biomedres.28.267
DOI Google Scholar
[78]

S.S. Nathan, K. Kalaivani, K. Murugan. Effects of neem limonoids on the malaria vector Anopheles stephensi Liston (Diptera: Culicidae). Acta Tropica, 2005, 96(1): 47−55. https://doi.org/10.1016/j.actatropica.2005.07.002
DOI Google Scholar
[79]

J.O. Ogidigo, E.A. Iwuchukwu, C.U. Ibeji, et al. Natural phyto, compounds as possible noncovalent inhibitors against SARS-CoV2 protease: Computational approach. Journal of Biomolecular Structure &Dynamics, 2022, 40(5): 2284−2301. https://doi.org/10.1080/07391102.2020.1837681
DOI Google Scholar
[80]

S. Mahapatra, R.J. Karnes, M.W. Holmes, et al. Novel molecular targets of azadirachta indica associated with inhibition of tumor growth in prostate cancer. The AAPS Journal, 2011, 13(3): 365−377. https://doi.org/10.1208/s12248-011-9279-4
DOI Google Scholar
[81]
T. Akihisa, Y. Nishimoto, E. Ogihara, et al. Nitric oxide production-inhibitory activity of limonoids from Azadirachta indica and Melia azedarach. Chemistry & Biodiversity, 2017, 14(6): e1600468.
DOI
[82]

S. Sharad, S. Kapur. Indian herb-derived phytoconstituent-based antiviral, antimicrobial and antifungal formulation: An oral rinse candidate for oral hygiene and the potential prevention of COVID-19 outbreaks. Pathogens, 2021, 10(9): 1130. https://doi.org/10.3390/pathogens10091130
DOI Google Scholar
[83]

A. Balkrishna, R. Mittal, V. Arya. Computational evidences of phytochemical mediated disruption of PLpro driven replication of SARS-CoV-2: A therapeutic approach against COVID-19. Current Pharmaceutical Biotechnology, 2021, 22(10): 1350−1359. https://doi.org/10.2174/1389201021999201110204116
DOI Google Scholar
[84]

A. Balkrishna, R. Mittal, G. Sharma, et al. Computational insights of phytochemical-driven disruption of RNA-dependent RNA polymerase-mediated replication of coronavirus: A strategic treatment plan against coronavirus disease 2019. New Microbes and New Infections, 2021, 41: 100878. https://doi.org/10.1016/j.nmni.2021.100878
DOI Google Scholar
[85]

B. Sultana, F. Anwar, R. Przybylski. Antioxidant activity of phenolic components present in barks of Azadirachta indica, Terminalia arjuna, Acacia nilotica, and Eugenia jambolana Lam. trees. Food Chemistry, 2007, 104(3): 1106−1114. https://doi.org/10.1016/j.foodchem.2007.01.019
DOI Google Scholar
[86]

G. Brahmachari. Neem—An omnipotent plant: A retrospection. ChemBioChem, 2004, 5(4): 408−421. https://doi.org/10.1002/cbic.200300749
DOI Google Scholar
[87]

M.J. Mitchell, S.L. Smith, S. Johnson, et al. Effects of the neem tree compounds azadirachtin, salannin, nimbin, and 6-desacetylnimbin on ecdysone 20-monooxygenase activity. Archives of Insect Biochemistry and Physiology, 1997, 35(12): 199−209. https://doi.org/10.1002/(SICI)1520-6327(1997)35:1/2<199::AID-ARCH18>3.0.CO;2-6
DOI Google Scholar
[88]

V.D. Dwivedi, I.P. Tripathi, S.K. Mishra. In silico evaluation of inhibitory potential of triterpenoids from Azadirachta indica against therapeutic target of dengue virus, NS2B-NS3 protease. Journal of Vector Borne Diseases, 2016, 53(2): 156−161.
Google Scholar
[89]

N. Baildya, A.A. Khan, N.N. Ghosh, et al. Screening of potential drug from Azadirachta Indica (Neem) extracts for SARS-CoV-2: An insight from molecular docking and MD-simulation studies. Journal of Molecular Structure, 2021, 1227: 129390. https://doi.org/10.1016/j.molstruc.2020.129390
DOI Google Scholar
[90]

S. Garg, A. Anand, Y. Lamba, et al. Molecular docking analysis of selected phytochemicals against SARS-CoV-2 Mpro receptor. Vegetos, 2020, 33(4): 766−781. https://doi.org/10.1007/s42535-020-00162-1
DOI Google Scholar
[91]
M.A. Veeraragavan, C.K. Sen, S.R. Kalidindi. Anti-diabetic activity of neem extract and synergistic combinations of urolithins A and B. Patent No. WO/2020/097014, 2020.
[92]

S. Vardhan, S.K. Sahoo. In silico ADMET and molecular docking study on searching potential inhibitors from limonoids and triterpenoids for COVID-19. Computers in Biology and Medicine, 2020, 124: 103936. https://doi.org/10.1016/j.compbiomed.2020.103936
DOI Google Scholar
[93]

M.H. Jameel, S. Saleem, M. Hashim, et al. A comparative study on characterizations and synthesis of pure lead sulfide (PbS) and Ag-doped PbS for photovoltaic applications. Nanotechnology Reviews, 2021, 10(1): 1484−1492. https://doi.org/10.1515/ntrev-2021-0100
DOI Google Scholar
[94]

M. Maruthupandy, Y. Zuo, J.S. Chen, et al. Synthesis of metal oxide nanoparticles (CuO and ZnO NPs) via biological template and their optical sensor applications. Applied Surface Science, 2017, 397: 167−174. https://doi.org/10.1016/j.apsusc.2016.11.118
DOI Google Scholar
[95]
F. Boscherini. Chapter 7–X-ray absorption fine structure in the study of semiconductor heterostructures and nanostructures. In: Characterization of Semiconductor Heterostructures and Nanostructures (Second Edition). Elsevier, 2013: 295–310.
DOI
[96]
G. Parihar, N. Balekar. Calotropis procera: A phytochemical and pharmacological review. Thai Journal of Pharmaceutical Sciences, 2016. 40(3): 115–131.
[97]

D. Rehana, D. Mahendiran, R.S. Kumar, et al. Evaluation of antioxidant and anticancer activity of copper oxide nanoparticles synthesized using medicinally important plant extracts. Biomedicine &Pharmacotherapy = Biomedecine &Pharmacotherapie, 2017, 89: 1067−1077. https://doi.org/10.1016/j.biopha.2017.02.101
DOI Google Scholar
[98]

M. Rafique, A.J. Shaikh, R. Rasheed, et al. A review on synthesis, characterization and applications of copper nanoparticles using green method. Nano, 2017, 12(4): 1750043. https://doi.org/10.1142/s1793292017500436
DOI Google Scholar
[99]

P. Kuppusamy, S. Ilavenil, S. Srigopalram, et al. Treating of palm oil mill effluent using Commelina nudiflora mediated copper nanoparticles as a novel bio-control agent. Journal of Cleaner Production, 2017, 141: 1023−1029. https://doi.org/10.1016/j.jclepro.2016.09.176
DOI Google Scholar
[100]

W.J. Aziz, H.A. Jassim. A new paradigm shift to prepare copper NPs using biological synthesis and evaluation of antimicrobial activity. Plant Archives, 2018, 18(2): 2020−2024.
Google Scholar
[101]

S. Shende, N. Gaikwad, S. Bansod. Synthesis and evaluation of antimicrobial potential of copper nanoparticle against agriculturally important phytopathogens. Synthesis, 2016, 1(4): 41−47.
Google Scholar
[102]

D.J. Manasa, K.R. Chandrashekar, D.J. Madhu Kumar, et al. Mussaenda frondosa L. mediated facile green synthesis of Copper oxide nanoparticles–Characterization, photocatalytic and their biological investigations. Arabian Journal of Chemistry, 2021, 14(6): 103184. https://doi.org/10.1016/j.arabjc.2021.103184
DOI Google Scholar
[103]

S.M.H. Akhter, F. Mohammad, S. Ahmad. Terminalia belerica mediated green synthesis of nanoparticles of copper, iron and zinc metal oxides as the alternate antibacterial agents against some common pathogens. BioNanoScience, 2019, 9(2): 365−372. https://doi.org/10.1007/s12668-019-0601-4
DOI Google Scholar
[104]

K. Pikula, V. Chaika, A. Zakharenko, et al. Comparison of the level and mechanisms of toxicity of carbon nanotubes, carbon nanofibers, and silicon nanotubes in bioassay with four marine microalgae. Nanomaterials, 2020, 10(3): E485. https://doi.org/10.3390/nano10030485
DOI Google Scholar
[105]

J.D. Robertson, L. Rizzello, M. Avila-Olias, et al. Purification of Nanoparticles by size and shape. Scientific reports, 2016, 6: 27494. https://doi.org/10.1038/srep27494
DOI Google Scholar
[106]

J.K. Suthar, R. Rokade, A. Pratinidi, et al. Purification of nanoparticles by liquid chromatography for biomedical and engineering applications. American Journal of Analytical Chemistry, 2017, 8(10): 617−624. https://doi.org/10.4236/ajac.2017.810044
DOI Google Scholar
[107]

L.L. Lazarus, C.T. Riche, N. Malmstadt, et al. Effect of ionic liquid impurities on the synthesis of silver nanoparticles. Langmuir, 2012, 28(45): 15987−15993. https://doi.org/10.1021/la303617f
DOI Google Scholar
[108]

J.M. Hasnain, B.A.M. Arif, B.R.M. Sufi, et al. A comparative DFT study of electronic and optical properties of Pb/Cd-doped LaVO4 and Pb/Cd-LuVO4 for electronic device applications. Computational Condensed Matter, 2023, 34: e00773. https://doi.org/10.1016/j.cocom.2022.e00773
DOI Google Scholar
[109]

F. Saeed, M. Ahmad, Samia, et al. Phosphorus-doped CoFe2O4 nanoparticles decorated nitrogen-doped graphene for efficient and stable electrocatalytic water splitting. International Journal of Hydrogen Energy, 2024, 59: 1196−1204. https://doi.org/10.1016/j.ijhydene.2024.01.035
DOI Google Scholar
[110]

R. Amin, S. Ullah, F. Saeed, et al. Study of mass transfer resistant effect during syn gas and hydrogen production through CO2/CH4 Dry reforming on La/Mg supported Co-Ni/MSU-S zeolite. The Lighthouse Journal of Natural Sciences, 2022, 1(2): 19−34.
Google Scholar
[111]

A. Ibrar, S.A. Shehzadi, F. Saeed, et al. Developing hybrid molecule therapeutics for diverse enzyme inhibitory action: Active role of coumarin-based structural leads in drug discovery. Bioorganic &Medicinal Chemistry, 2018, 26(13): 3731−3762. https://doi.org/10.1016/j.bmc.2018.05.042
DOI Google Scholar
[112]

Z. Hussain, K.M. Khan, A. Ullah, et al. Preparation of bioorganic rechargeable battery using urea and chickpea protein for the storage and generation of electrical power. Journal of the Chemical society of Pakistan, 2013, 35(5): 1412−1416.
Google Scholar
Publication history
Copyright
Acknowledgements
Rights and permissions

Publication history

Received: 26 December 2023
Revised: 21 January 2024
Accepted: 13 February 2024
Published: 26 March 2024

Copyright

© The Author(s) 2024.

Acknowledgements

Acknowledgements

We acknowledge the support from National Natural Science Foundation of China (No. 61975148).

Rights and permissions

This is an open-access article distributed under  the  terms  of  the  Creative  Commons  Attribution  4.0 International  License (CC BY) (http://creativecommons.org/licenses/by/4.0/), which  permits  unrestricted  use,  distribution,  and reproduction in any medium, provided the original author and source are credited.

Return