AI Chat Paper
Discover the SciOpen Platform and Achieve Your Research Goals with Ease.
Search articles, authors, keywords, DOl and etc.
{{expandStatus?'Exit ':''}}Advanced Search
Plant extracts play an essential role in bioreducing metal ions and capping the resultant nanomaterials. We report the green synthesis of indole pyrazole-capped cadmium sulfide quantum dots (TRPIDC-CH3CdSQDs) using Moringa oleifera leaf extract and indole pyrazole ligand. Morphological analysis using a high-resolution electron microscope indicated the presence of spherical particles with an average diameter of 4.5 nm. The ultraviolet–visible (UV–Vis) spectroscopy results exhibited a bandgap energy of 2.95 eV, and phytochemical deposition on the TRPIDC-CH3CdSQDs was confirmed by Fourier transform infrared (FTIR). The cytotoxicity analysis was conducted using the 3-(4,5)-dimethylthiahiazo(-z-y1)-3,5-di-phenytetrazoliumromide (MTT) assay on two cancer ((breast (MCF-7) and lung (A549)) cells and a normal human embryonic kidney (HEK293) cell. Low cytotoxic activity was found for TRPIDC-CH3CdSQDs against all three cell types, the highest activity percentage being 63.80% against MCF-7 and TRPIDC-CH3CdSQDs show a dose-dependent increase in cytotoxic activity. Spectroscopic interaction studies were undertaken with human serum albumin using UV–Vis and fluorescence spectroscopy. The interactions between TRPIDC-CH3CdSQDs and human serum albumin were hydrophobic. Using corrected fluorescence data, the Stern–Volmer constant and binding constant were 2.06 × 103 and 2.85 × 103 mol·L−1, respectively. The findings indicate its potential to be used in drug delivery.
J. Rajangam, P. Sampathi, N.N. Palei, et al. Green synthesis, characterization and antiepileptic activity of herbal nanoparticles of Mimusops elengi in mice. Nano Biomedicine and Engineering, 2022, 14(4): 295−307. https://doi.org/10.5101/nbe.v14i4.p295-307
B.A. de Marco, B.S. Rechelo, E.G. Tótoli, et al. Evolution of green chemistry and its multidimensional impacts: A review. Saudi Pharmaceutical Journal, 2019, 27(1): 1−8. https://doi.org/10.1016/j.jsps.2018.07.011
P. Rauwel, S. Küünal, S. Ferdov, et al. A review on the green synthesis of silver nanoparticles and their morphologies studied via TEM. Advances in Materials Science and Engineering, 2015, 2015: 682749. https://doi.org/10.1155/2015/682749
Z. Machalova, M. Sajfrtova, R. Pavela, et al. Extraction of botanical pesticides from Pelargonium graveolens using supercritical carbon dioxide. Industrial Crops and Products, 2015, 67: 310−317. https://doi.org/10.1016/j.indcrop.2015.01.070
A.C. Mendes Hacke, D. Lima, S. Kuss. Green synthesis of electroactive nanomaterials by using plant-derived natural products. Journal of Electroanalytical Chemistry, 2022, 922: 116786. https://doi.org/10.1016/j.jelechem.2022.116786
E. Alzahrani, A.T. Alkhudidy. Synthesis, optimization, and characterization of ecofriendly production of gold nanoparticles using lemon peel extract. International Journal of Analytical Chemistry, 2021, 2021: 7192868. https://doi.org/10.1155/2021/7192868
B.B. Zhao, T. Lan, H. Li, et al. Antioxidation activity of Moringa oleifera Lam. leaves extract on soybean oil during both storage and thermal treatment. Journal of Food Processing and Preservation, 2019, 43(8): e13975. https://doi.org/10.1111/jfpp.13975
K. El-bakry, E.-s. Toson, M. Serag, et al. Hepatoprotective effect of Moringa oleifera leaves extract against carbon tetrachloride-induced liver damage in rats. World journal of pharmaceutical research, 2016, 5(5): 76−89.
J. Seetha, U.M. Mallavarapu, P. Akepogu, et al. Biosynthesis and study of bimetallic copper and silver nanoparticles on cellulose cotton fabrics using Moringa oliefiera leaf extraction as reductant. Inorganic and Nano-Metal Chemistry, 2020, 50(9): 828−835. https://doi.org/10.1080/24701556.2020.1725571
N. Matinise, X.G. Fuku, K. Kaviyarasu, et al. ZnO nanoparticles via Moringa oleifera green synthesis: Physical properties & mechanism of formation. Applied Surface Science, 2017, 406: 339−347. https://doi.org/10.1016/j.apsusc.2017.01.219
E. Kalugendo, P. Kousalya. Synthesis of silver nanoparticles using Moringa oleifera seeds, Glycyrrhiza glabra stems, and its anti-methicillin-resistant Staphylococcus aureus activity. Asian Journal of Pharmaceutical and Clinical Research, 2019, 12(2): 368−370. https://doi.org/10.22159/ajpcr.2019.v12i2.28863
M. Borovaya, Y. Pirko, T. Krupodorova, et al. Biosynthesis of cadmium sulphide quantum dots by using Pleurotus ostreatus (Jacq.) P. Kumm. Biotechnology &Biotechnological Equipment, 2015, 29(6): 1156−1163. https://doi.org/10.1080/13102818.2015.1064264
H. Mohd Yusof, N. Abdul Rahman, R. Mohamad, et al. Microbial mediated synthesis of silver nanoparticles by Lactobacillus plantarum TA4 and its antibacterial and antioxidant activity. Applied Sciences, 2020, 10(19): 6973. https://doi.org/10.3390/app10196973
G. Gahlawat, A.R. Choudhury. A review on the biosynthesis of metal and metal salt nanoparticles by microbes. RSC Advances, 2019, 9(23): 12944−12967. https://doi.org/10.1039/C8RA10483B
D. Verma, N. Gulati, S. Kaul, et al. Protein based nanostructures for drug delivery. Journal of Pharmaceutics, 2018, 2018: 9285854. https://doi.org/10.1155/2018/9285854
J.M. Jacob, S. Sharma, R.M. Balakrishnan. Exploring the fungal protein cadre in the biosynthesis of PbSe quantum dots. Journal of Hazardous Materials, 2017, 324: 54−61. https://doi.org/10.1016/j.jhazmat.2015.12.05
Z. Al-Shalabi, P.M. Doran. Biosynthesis of fluorescent CdS nanocrystals with semiconductor properties: Comparison of microbial and plant production systems. Journal of Biotechnology, 2016, 223: 13−23. https://doi.org/10.1016/j.jbiotec.2016.02.018
G.R. Bardajee, Z. Hooshyar. Interaction of a novel starch-capped CdS quantum dots with human serum albumin and bovine serum albumin. Starch, 2016, 68(3-4): 329−338. https://doi.org/10.1002/star.201500092
T.R. Makhanya, R.M. Gengan, K. Kasumbwe. Synthesis of fused indolo-pyrazoles and their antimicrobial and insecticidal activities against Anopheles arabiensis mosquito. ChemistrySelect, 2020, 5(9): 2756−2762. https://doi.org/10.1002/slct.201904620
S. Dadiboyena, A. Nefzi. Synthesis of functionalized tetrasubstituted pyrazolyl heterocycles–A review. European Journal of Medicinal Chemistry, 2011, 46(11): 5258−5275. https://doi.org/10.1016/j.ejmech.2011.09.016
C. Otitolaiye, A. Omonkhua, K. Oriakhi, et al. Phytochemical analysis and in vitro antioxidant potential of aqueous and ethanol extracts of Irvingia gabonensis stem bark. Pharmacognosy Research, 2023, 15(2): 363−372. https://doi.org/10.5530/pres.15.2.039
K. Shivaji, S. Mani, P. Ponmurugan, et al. Green-synthesis-derived CdS quantum dots using tea leaf extract: Antimicrobial, bioimaging, and therapeutic applications in lung cancer cells. ACS Applied Nano Materials, 2018, 1(4): 1683−1693. https://doi.org/10.1021/acsanm.8b00147
X.Q. Wu, C. Huang, Y.M. Jia, et al. Novel coumarin-dihydropyrazole thio-ethanone derivatives: Design, synthesis and anticancer activity. European Journal of Medicinal Chemistry, 2014, 74: 717−725. https://doi.org/10.1016/j.ejmech.2013.06.014
S. Prasanth, C. Sudarsanakumar. Elucidating the interaction of L-cysteine-capped selenium nanoparticles and human serum albumin: Spectroscopic and thermodynamic analysis. New Journal of Chemistry, 2017, 41(17): 9521−9530. https://doi.org/10.1039/c7nj00477j
A.V. Pansare, A.A. Shedge, V.R. Patil. Discrete SeNPs-macromolecule binding manipulated by hydrophilic interaction. International Journal of Biological Macromolecules, 2018, 107: 1982−1987. https://doi.org/10.1016/j.ijbiomac.2017.10.065
M. Mahanthappa, M.A. Savanur, B. Puthusseri, et al. Spectroscopic and electrochemical studies on the molecular interaction between copper sulphide nanoparticles and bovine serum albumin. Journal of Materials Science, 2018, 53(1): 202−214. https://doi.org/10.1007/s10853-017-1521-8
P. Ilanko, P.A. McDonnell, S. van Vuuren, et al. Interactive antibacterial profile of Moringa oleifera Lam. extracts and conventional antibiotics against bacterial triggers of some autoimmune inflammatory diseases. South African Journal of Botany, 2019, 124: 420−435. https://doi.org/10.1016/j.sajb.2019.04.008
P.E. Das, I.A. Abu-Yousef, A.F. Majdalawieh, et al. Green synthesis of encapsulated copper nanoparticles using a hydroalcoholic extract of Moringa oleifera leaves and assessment of their antioxidant and antimicrobial activities. Molecules, 2020, 25(3): 555. https://doi.org/10.3390/molecules25030555
S. Suresh, A.S. Chhipa, M. Gupta, et al. Phytochemical analysis and pharmacological evaluation of methanolic leaf extract of Moringa oleifera Lam. in ovalbumin induced allergic asthma. South African Journal of Botany, 2020, 130: 484−493. https://doi.org/10.1016/j.sajb.2020.01.046
K. Kandasamy, M. Venkatesh, Y.A. Syed Khadar, et al. One-pot green synthesis of CdS quantum dots using Opuntia ficus-indica fruit sap. Materials Today:Proceedings, 2020, 26: 3503−3506. https://doi.org/10.1016/j.matpr.2019.06.003
G.B. Jegadeesan, K. Srimathi, N. Santosh Srinivas, et al. Green synthesis of iron oxide nanoparticles using Terminalia bellirica and Moringa oleifera fruit and leaf extracts: Antioxidant, antibacterial and thermoacoustic properties. Biocatalysis and Agricultural Biotechnology, 2019, 21: 101354. https://doi.org/10.1016/j.bcab.2019.101354
E.SR. El-Sayed, H.K. Abdelhakim, A.S. Ahmed. Solid-state fermentation for enhanced production of selenium nanoparticles by gamma-irradiated Monascus purpureus and their biological evaluation and photocatalytic activities. Bioprocess and Biosystems Engineering, 2020, 43(5): 797−809. https://doi.org/10.1007/s00449-019-02275-7
R. Vivek, R. Thangam, K. Muthuchelian, et al. Green biosynthesis of silver nanoparticles from Annona squamosa leaf extract and its in vitro cytotoxic effect on MCF-7 cells. Process Biochemistry, 2012, 47(12): 2405−2410. https://doi.org/10.1016/j.procbio.2012.09.025
M.A. Farah, M.A. Ali, S.M. Chen, et al. Silver nanoparticles synthesized from Adenium obesum leaf extract induced DNA damage, apoptosis and autophagy via generation of reactive oxygen species. Colloids and Surfaces B:Biointerfaces, 2016, 141: 158−169. https://doi.org/10.1016/j.colsurfb.2016.01.027
M. Ishtikhar, G. Rabbani, S. Khan, et al. Biophysical investigation of thymoquinone binding to ‘N’ and ‘B’ isoforms of human serum albumin: Exploring the interaction mechanism and radical scavenging activity. RSC Advances, 2015, 5(24): 18218−18232. https://doi.org/10.1039/c4ra09892g
G. Rezanejade Bardajee, Z. Hooshyar, M. Rezaei, et al. Spectroscopic studies on the interactions of capped CdS quantum dots with human serum albumin (HSA) and bovine serum albumin (BSA). Inorganic and Nano-Metal Chemistry, 2017, 47(5): 688−696. https://doi.org/10.1080/15533174.2016.1186098
S. Devi, S. Tyagi. Fluorescent determination of trinitrotoluene with bovine serum albumin mediated enhancement of thioglycolic acid capped cadmium selenium quantum dots. Instrumentation Science &Technology, 2019, 47(3): 292−311. https://doi.org/10.1080/10739149.2018.1531019
This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International License (CC BY) (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
京公网安备11010802044758号