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Research Article | Open Access

Green Synthesis of Piperine Loaded Gold/Triton X-100 Nanoconjugates: In-vitro Evaluation of Biocompatibility and Anti-Oxidant Activity

Muthusamy Prabakaran1, Periakaruppan Nithya1, Vellaikannu Kalaiarasi2, Kalaivani Raman3, Susaimanickam Arul Antony1( ), Mani Gajendiran3( )
PG and Research, Department of Chemistry, Presidency College, Chennai 600005, India
Department of Chemistry, Karpaga Vinayaga College of Engineering and Technology, Palaynoor, Maduranthakam, Tamilnadu-603308, India
Department of Chemistry, School of Basic Sciences, Vels Institute of Science Technology and Advanced Studies (Vels University), Chennai 600117, India
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Abstract

In this research, gold nanoparticles (Au NPs) were synthesized by a green chemical approach using the organic natural product piperine isolated from the black pepper. The piperine-Au NPs attached on the Triton X-100 and they were characterized by ultraviolet-visible absorption spectroscopy (UV-Vis), dynamic light scattering spectroscopy (DLS), X-ray powder diffraction (XRD), transmission electron microscopy (TEM), and energy dispersive X-ray spectroscopy (EDS). The TEM analysis confirmed the spherical shape of Au NPs with a diameter of 17-30 nm. The XRD analysis revealed that the Au NPs exhibited fcc crystal structure with an average crystallite size of 26 nm. The biocompatibility of the piperine-AuNPs-Triton X-100 nanoconjugates were examined on Hep-G2 cells. The piperine-AuNPs-Triton X-100 nanoconjugates exhibited better anti-oxidant activity.

Keywords

Gold nanoparticlesIn vitro cytotoxicityPiperineTriton X-100Anti-oxidant activity

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Nano Biomedicine and Engineering
Volume 11 Issue 2,
June 2019
Pages 192-199
DOI: 10.5101/nbe.v11i2.p192-199
Cite this article:
Prabakaran M, Nithya P, Kalaiarasi V, et al. Green Synthesis of Piperine Loaded Gold/Triton X-100 Nanoconjugates: In-vitro Evaluation of Biocompatibility and Anti-Oxidant Activity. Nano Biomedicine and Engineering, 2019, 11(2): 192-199. https://doi.org/10.5101/nbe.v11i2.p192-199

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Received: 25 November 2018
Accepted: 09 June 2019
Published: 21 June 2019
© Muthusamy Prabakaran, Periakaruppan Nithya, Vellaikannu Kalaiarasi, Kalaivani Raman, Susaimanickam Arul Antony, and Mani Gajendiran.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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