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Review | Open Access

Biological Application of Digital Microfluidics Technology

Bin Liu1, Yan Deng1,2, Binbing Qin1, Zhiyang Li1, Nongyue He1,2( )
State Key Laboratory of Bioelectronics, School of Biological Science and Medical Engineering, Southeast University, Nanjing, 210096, P.R. China
Hunan Key Laboratory of Green Packaging and Application of Biological Nanotechnology, Hunan University of Technology, Zhuzhou 412008, China
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Abstract

Digital microfluidics technology offers a platform for developing diagnostic applications with the advantages of portability, sample and reagent volume reduction, faster analysis, increased automation, low power consumption, compatibility with mass manufacturing and high throughput. In addition to diagnostics, digital microfluidics is finding use in nucleic acid analysis, peptide and protein analysis, cell analysis, drug analysis and delivery and immunization analysis. In this review, we describe these applications, their implementation, and associated design issues. As other review in the digital microfluidics technology, there have been and will be unexpected developments as DMF matures, but we predict that the future is bright for this promising technology at the last section.

Keywords

Digital microfluidics technologyNucleic acid analysisPeptide and protein analysisCell analysisDrug analysis and delivery

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Nano Biomedicine and Engineering
Volume 2 Issue 2,
June 2010
Pages 149-154
DOI: 10.5101/nbe.v2i2.p149-154
Cite this article:
Liu B, Deng Y, Qin B, et al. Biological Application of Digital Microfluidics Technology. Nano Biomedicine and Engineering, 2010, 2(2): 149-154. https://doi.org/10.5101/nbe.v2i2.p149-154

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Received: 15 May 2010
Accepted: 22 June 2010
Published: 18 July 2010
© 2010 B. Liu et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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