Nanostructured Calcium Phosphates: Preparation and Their Application in Biomedicine

Feng Chen; Yingjie Zhu; Jin Wu; Peng Huang; Daxiang Cui

doi:10.5101/nbe.v4i1.p41-49

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Review | Open Access

Nanostructured Calcium Phosphates: Preparation and Their Application in Biomedicine

Feng Chen^{^a^,^b}, Yingjie Zhu^{^b}(

), Jin Wu^{^b}, Peng Huang^{^a}, Daxiang Cui^{^a}(

)

Department of Bio-Nano Science and Engineering, Research Institute of Micro/Nano Science and Technology, Shanghai Jiao Tong University, Shanghai 200240, P. R. China

State Key Laboratory of High Performance Ceramics and Superfine Microstructure, Shanghai Institute of Ceramics, Chinese Academy of Sciences, Shanghai 200050, P. R. China

Show Author Information

Abstract

Due to the similar chemical properties to the inorganic component in calcified tissues, synthetic calcium phosphate has been considered as ideal biomaterials with excellent biocompatibility. Nanostructured calcium phosphate materials play an important role in the formation of hard tissues in nature. It is reported that calcium phosphates materials in nano-size can mimic the dimensions of constituent components of calcified tissues. Recently, the synthesis and application of nanostructured calcium phosphate materials have become a very hot field. Lots of methods have been reported to prepare nanostructured calcium phosphate, and various morphologies including nanoparticles, plate-like nanocrystals, nano-needles, whiskers/fibres/wires, mesoporous, nanotubes, nano-blades, and powders with three-dimensional (3-D) structures have been obtained. More studies of nanostructured calcium phosphates are expected in biomedical area, such as tissue engineering scaffolds, drug/gene delivery systems and multifunctional systems. In this article, the synthesis and application of nanostructured calcium phosphates are reviewed and discussed.

Keywords

Hydroxyapatite Nanostructure Drug Delivery Tissue Engineering Gene Delivery Biomedicine Calcium Phosphate

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Nano Biomedicine and Engineering

Volume 4 Issue 1,
March 2012

Pages 41-49

DOI: 10.5101/nbe.v4i1.p41-49

Cite this article:

Chen F, Zhu Y, Wu J, et al. Nanostructured Calcium Phosphates: Preparation and Their Application in Biomedicine. Nano Biomedicine and Engineering, 2012, 4(1): 41-49. https://doi.org/10.5101/nbe.v4i1.p41-49

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Published: 31 March 2012

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.