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Review | Open Access

Superoxide Dismutase, A Potential Theranostics Against Oxidative Stress Caused by Nanomaterials

Chao Li, Daxiang Cui( )
Department of Bio-Nano Science and Engineering, Key Laboratory for Thin Film and Micro fabrication Technology of Ministry of Education, National Key Laboratory of Micro/Nano Fabrication Technology, Research Institute of Micro/Nano Science and Technology, Shanghai Jiao Tong University, Shanghai, 200240, P.R. China
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Abstract

Nanomaterials can result in oxidative stress damage, how to prevent oxidative stress caused by nanomaterialshave become our concerns. Superoxide dismutase (SOD) performs some special functions inside the living cells such as combating with the reactive oxygen species (ROS), interfering with the injured made by the hydrogen peroxide (H2O2), and repairing the damage induced by these ROS, exhibiting great application prospects in clinical therapy. Herein we review the main advances of SOD and its high efficient delivery systems, and explore the issue, challenges, and prospects with the aim of developing novel nanoscaletheranostics against oxidative stress-induced damages caused nanomaterials.

Keywords

NanomaterialNanocarrierDrug delivery systemSuperoxide dismutase

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Nano Biomedicine and Engineering
Volume 4 Issue 4,
December 2012
Pages 195-206
DOI: 10.5101/nbe.v4i4.p195-206
Cite this article:
Li C, Cui D. Superoxide Dismutase, A Potential Theranostics Against Oxidative Stress Caused by Nanomaterials. Nano Biomedicine and Engineering, 2012, 4(4): 195-206. https://doi.org/10.5101/nbe.v4i4.p195-206

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Published: 31 December 2012
© 2012 C. Li et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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