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Review | Open Access

The True Complexity of Photothermal Therapy: A Brief Perspective

Gabriel Alfranca1,2,3Daxiang Cui2Jesus Martinez de la Fuente1,2,3( )
Institute of Nano Biomedicine and Engineering, Department of Instrument Science and Engineering, Shanghai Engineering Centre for Intelligent Diagnosis and Treatment Instrument. Shanghai Jiao Tong University, Shanghai 200240, China
Instituto de Ciencia de los Materiales de Aragón (ICMA-CSIC/University of Zaragoza) C/Pedro Cerbuna 12, 50009, Zaragoza, Spain
Centro de Investigación Biomédica en red en Bioingenieria Biomateriales y Nanomedicina (CIBER-BBN), Zaragoza, Spain
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Abstract

Despite its undoubted potential, recent studies have began to highlight the complex processes of photothermal therapy. In this perspective, we tackle several issues that affect current research on photothermal therapy, such as the influence of other factors produced in the process, for instance reactive oxygen species or vapor nanobubbles. After focusing on several of the aspects of photothermal therapy that need further clarification, we step back and see this therapy from a wider angle in order to identify its weaknesses. Finally, we briefly summarize what we consider should be the orientation and key focus of future researches in order to establish the full potential of this rapidly advancing and promising therapy.

References

[1]

D. de Melo-Diogo, C. Pais-Silva, D.R. Dias, et al., Strategies to improve cancer photothermal therapy mediated by nanomaterials. Adv. Healthc. Mater., 2017: 1700073.

[2]

M.P. Stewart, A. Sharei, X. Ding, et al., Break and enter: in vitro and ex vivo strategies for intracellular delivery. Nature, 2016, 538: 183-192.

[3]

R.R. Castillo, M. Colilla, and M. Vallet-Regí, Advances in mesoporous silica-based nanocarriers for co-delivery and combination therapy against cancer. Expert Opin. Drug Deliv., 2017, 14: 229-243.

[4]

B. Liu, C. Li, Z. Cheng, et al., Functional nanomaterials for near-infrared-triggered cancer therapy. Biomater. Sci., 2016, 4: 890-909.

[5]

W. Qin, G. Huang, Z. Chen, et al., Nanomaterials in targeting cancer stem cells for cancer therapy. Front. Pharmacol., 2017, 8: 1.

[6]

Y. Oh, J.O. Jin, and J. Oh, Photothermal-triggered control of sub-cellular drug accumulation using doxorubicin-loaded single-walled carbon nanotubes for the effective killing of human breast cancer cells. Nanotechnology, 2017, 28: 125101.

[7]

H. Wang, R. Zhao, Y. Li, et al., Aspect ratios of gold nanoshell capsules mediated melanoma ablation by synergistic photothermal therapy and chemotherapy. Nanomedicine, 2016, 12: 439-448.

[8]

L. Li, R.H. Leila, M. Yao, et al., CuS nanoagents for photodynamic and photothermal therapies: phenomena and possible mechanisms. Photodiagnosis Photodyn. Ther., 2017, 19: 5-14.

[9]

C. Bao, N. Beziere, P. del Pino, et al., Gold nanoprisms as optoacoustic signal nanoamplifiers for in vivo bioimaging of gastrointestinal cancers. Small, 2013, 9: 68-74.

[10]

P. Huang, P. Rong, J. Lin, et al., Triphase interface synthesis of plasmonic gold bellflowers as near-infrared light mediated acoustic and thermal theranostics. J. Am. Chem. Soc., 2014, 136: 8307-8313.

[11]

J. Zhang, F. Xia, Y. Yang, et al., Human CIK cells loaded with gold nanoprisms as theranostic platform for targeted photoacoustic imaging and enhanced immuno-photothermal combined therapy. Nano Biomed. Eng., 2016, 8: 109-124.

[12]

M. Aioub, S.R. Panikkanvalappil, and M.A. El-Sayed, Platinum-coated gold nanorods: Efficient reactive oxygen scavengers that prevent oxidative damage toward healthy, untreated cells during plasmonic photothermal therapy. ACS Nano, 2016, 11: 579-586.

[13]

L. Minai, D. Yeheskely-Hayon, and D. Yelin, High levels of reactive oxygen species in gold nanoparticle-targeted cancer cells following femtosecond pulse irradiation. Sci. Rep., 2013, 3: 2146.

[14]

R. Xiong, K. Raemdonck, K. Peynshaert, et al., Comparison of gold nanoparticle mediated photoporation: Vapor nanobubbles outperform direct heating for delivering macromolecules in live cells. ACS Nano, 2014, 8: 6288-6296.

[15]

M. Pérez-Hernández, P. del Pino, S.G. Mitchell, et al., Dissecting the molecular mechanism of apoptosis during photothermal therapy using gold nanoprisms. ACS Nano, 2015, 9: 52-61.

[16]

J. Kim, J. Kim, C. Jeong, and W.J. Kim, Synergistic nanomedicine by combined gene and photothermal therapy. Advanced Drug Delivery Reviews, 2016, 98: 99-112.

Nano Biomedicine and Engineering
Pages 129-134
Cite this article:
Alfranca G, Cui D, de la Fuente JM. The True Complexity of Photothermal Therapy: A Brief Perspective. Nano Biomedicine and Engineering, 2017, 9(2): 129-134. https://doi.org/10.5101/nbe.v9i2.p129-134

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Received: 23 May 2017
Accepted: 05 June 2017
Published: 08 June 2017
© 2017 Gabriel Alfranca, Daxiang Cui, and Jesus Martinez de la Fuente.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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