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Traditional tissue engineering scaffolds commonly consists of straight rods, inducing abrupt structure transition as well as large stress concentration on the rods’ intersections. Aiming to overcome this challenge, the triply periodic minimal surface (TPMS) scaffolds offer advantages like high surface area to volume ratio and less stress concentration with smooth surface joints. Especially, gradient porous scaffolds have received extensive attention in the research field of tissue engineering because they can provide an appropriate microenvironment for cell growth and tissue regeneration. However, there are only few studies on how to design the TPMS scaffold with gradient structure. In this paper, a parametric digital modeling method was utilized to design TPMS scaffolds, generating different kinds of gradient TPMS structures. The equivalent stress and strain of the proposed scaffolds were simulated by finite element (FE) models and the equivalent stress cloud diagrams under certain load conditions were obtained. The relations between the TPMS structure type, porosity, and the period number to the mechanical properties of the scaffolds were analyzed. Typical and gradient TPMS scaffold models were printed through FDM and SLA, validating the designing methods and the performance of the TPMS scaffold.
Zhang L, Liu H, Yao H, et al. Preparation, microstructure, and properties of ZrO2(3Y)/Al2O3 bioceramics for 3D printing of all-ceramic dental implants by vat photopolymerization. Chinese Journal of Mechanical Engineering: Additive Manufacturing Frontiers 2022;1(2):100023.
Shao H, Nian Z, Jing Z, et al. Additive manufacturing of hydroxyapatite bioceramic scaffolds with projection based 3D printing. Chinese Journal of Mechanical Engineering: Additive Manufacturing Frontiers 2022;1:100021.
Hu Y, Wu B, Xiong Y, et al. Cryogenic 3D printed hydrogel scaffolds loading exosomes accelerate diabetic wound healing. Chemical Engineering Journal 2021;426:130634.
Tian W, Liu X, Ren K, et al. Biomimetic Janus film fabricated via cryogenic electrospinning for gastrointestinal mucosa repair. Materials & Design 2023;228:111839.
Wang N, Chang S, Li G, et al. Effects of various processing parameters on mechanical properties and biocompatibility of Fe-based bulk metallic glass processed via selective laser melting at constant energy density. Chinese Journal of Mechanical Engineering: Additive Manufacturing Frontiers 2022;1:100038.
Bai J, Bu G. Progress in 4D printing technology. Journal of Advanced Manufacturing Science and Technology 2022; 2(1): 2022001.
Jung Y, Chu KT, Torquato S. A variational level set approach for surface area minimization of triply-periodic surfaces. Journal of Computational Physics 2007;223:711-730.
Restrepo S, Ocampo S, Ramírez JA, et al. Mechanical properties of ceramic structures based on Triply Periodic Minimal Surface (TPMS) processed by 3D printing. Journal of Physics: Conference Series 2017;935:012036.
Ma S, Tang Q, Zhu C, et al. Laser powder bed fusion-built Ti6Al4V bone scaffolds composed of sheet and strut-based porous structures: morphology. Mechanical Properties, and Biocompatibility 2022;1:100051.
Melchels FP, Barradas AM, Van Blitterswijk CA, et al. Effects of the architecture of tissue engineering scaffolds on cell seeding and culturing. Acta Biomaterialia 2010;6:4208-4217.
Bobbert FSL, Lietaert K, Eftekhari AA, et al. Additively manufactured metallic porous biomaterials based on minimal surfaces: a unique combination of topological, mechanical, and mass transport properties. Acta Biomaterialia 2017; 53:572-584.
Montazerian H, Davoodi E, Asadi-Eydivand M, et al. Porous scaffold internal architecture design based on minimal surfaces: a compromise between permeability and elastic properties, Materials & Design 2017; 126:98-114.
Yang L, Mertens R, Ferrucci M, et al. Continuous graded gyroid cellular structures fabricated by selective laser melting: design, manufacturing and mechanical properties. Materials & Design 2019; 162: 394-404.
Yang H, Qi J. The unit design and analysis of artificial bone scaffold structure. Machine Design and Manufacturing Engineering 2018; 47: 17-20.
Zhu L, Li L, Shi L, et al. Mechanical characterization of 3D printed multi-morphology porous Ti6Al4V scaffolds based on triply periodic minimal surface architectures. American Journal of Translational Research 2018;10:3443-3454.
Vijayavenkataraman S, Zhang L, Zhang S, et al. Triply periodic minimal surfaces sheet scaffolds for tissue engineering applications: an optimization approach toward biomimetic scaffold design. ACS Applied Bio Materials 2018;1:259-269.
Wang P, Cui J. Metal plastic forming mechanics. Beijing: Metallurgical Industry Press, 2006.
Karakoc A. Region TPMS - Region based triply periodic minimal surfaces (TPMS) for 3D printed multiphase bone scaffolds with exact porosity values. SoftwareX 2021;16:100835.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License http://creativecommons.org/licenses/by/4.0)，which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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