AI Chat Paper
Note: Please note that the following content is generated by AMiner AI. SciOpen does not take any responsibility related to this content.
{{lang === 'zh_CN' ? '文章概述' : 'Summary'}}
{{lang === 'en_US' ? '中' : 'Eng'}}
Chat more with AI
PDF (1.2 MB)
Collect
Submit Manuscript AI Chat Paper
Show Outline
Outline
Show full outline
Hide outline
Outline
Show full outline
Hide outline
Research Article | Open Access

The Effect of Aluminum Nanoparticles on Vaccine-dosed Rabbits Investigated Using Cyclic Voltammetry

Mohammed Abdul Hameed Younis1Muhammed Mizher Radhi2Emad Abbas Jaffar Al-Mulla3( )
Department of Anesthesia Techniques, College of Health and Medical Techniques, Middle Technical University, Baghdad, Iraq
Department of Radiological Techniques, College of Health and Medical Technology, Middle Technical University, Baghdad, Iraq
College of Health and Medical Techniques, Al-Furat Al-Awsat Technical University, Al-Kufa, Iraq
Show Author Information

Graphical Abstract

Abstract

This study investigates the effect of aluminum nanoparticles (AL NPs) on vaccines (e.g., poliomyelitis and bacille Calmette–Guérin (BCG) vaccines). Cyclic voltammetry was used to determine the extent of its effect on the blood composition using an in vivo study on blood samples obtained from rabbits injected with poliomyelitic virus and BCG vaccines across a period of four weeks. The oxidation current peaks of the vaccines in the rabbit blood samples were enhanced with increasing doses of AL NPs. AL NPs acted as oxidative reagents to the rabbit blood components.

References

[1]

M.M. Radhi, A.A. Obaid, W.H. Hoidy. Electrochemical analysis using nano-sensor of stevia herb as a healthful alternative sugar. Nano Biomedicine and Engineering, 2021, 13: 207−211. https://doi.org/10.5101/nbe.v13i2.p207-211

[2]

M.M. Radhi, H.N. Abdullah, S.A. Al-Asadi, et al. Electrochemical oxidation effect of ascorbic acid on mercury ions in blood sample using cyclic voltammetry. International Journal of Industrial Chemistry, 2015, 6: 311−316. https://doi.org/10.1007/s40090-015-0053-9

[3]

M.M. Radhi, H.N. Abdullah, M. S. Jabir, et al. Electrochemical effect of ascorbic acid on redox current peaks of CoCl2 in blood medium. Nano Biomedicine and Engineering, 2017, 9: 103−106. https://doi.org/10.5101/nbe.v9i2.p103-106

[4]

M.M. Radhi, A.A.A. Albakry, A.M. Jassim, et al. Electrochemical study of Pb(II) in present of each ascorbic acid, glucose, urea and uric acid using blood medium as an electrolyte. Nano Biomedicine and Engineering, 2016, 8: 9−15. https://doi.org/10.1007/10.5101/nbe.v8i1.p9-15

[5]

M.M. Radhi, M.A.A. Alasadyb, M.S. Jabir. Electrochemical oxidation effect of nicotine in cigarette tobacco on a blood medium mediated by GCE using cyclic voltammetry. Portugaliae Electrochimica Acta, 2020, 38: 139−148. https://doi.org/10.4152/pea.202003139

[6]

A.L. Abdullah, M.M. Radhi, I.N. Khelkal, et al. Azithromycin nanoparticles: Cyclic voltammetric study in human blood serum samples at electrochemical analysis. Romanian Journal of Neurology, 2020, 19: 5−11. https://doi.org/10.37897/RJN.2020.1.1

[7]

A. Nazarizadeh, A.H. Staudacher, N.L. Wittwer, et al. Aluminium nanoparticles as efficient adjuvants compared to their microparticle counterparts: Current progress and perspectives. International Journal of Molecular Sciences, 2022, 23: 4707. https://doi.org/10.3390/ijms23094707

[8]

A.E. Gregory, R. Titball, D. Williamson. Vaccine delivery using nanoparticles. Frontiers in Cellular and Infection Microbiology, 2013, 3: 13. https://doi.org/10.3389/fcimb.2013.00013

[9]

N. Wang, C. Wei, Z. Zhang, et al. Aluminum nanoparticles acting as a pulmonary vaccine adjuvant-delivery system (VADS) able to safely elicit robust systemic and mucosal immunity. Journal of Inorganic and Organometallic Polymers and Materials, 2020, 30: 4203−4217. https://doi.org/10.1007/s10904-020-01572-z

[10]

S. Dhakal, G.J. Renukaradhya. Nanoparticle-based vaccine development and evaluation against viral infections in pigs. Veterinary Research, 2019, 50: 90. https://doi.org/10.1186/s13567-019-0712-5

[11]

G. Guerrini, D. Magrì, S. Gioria, et al. Characterization of nanoparticles-based vaccines for COVID-19. Nature Nanotechnology, 2022, 17: 570−576. https://doi.org/10.1038/s41565-022-01129-w

[12]

B.Y.S. Kim, J.T. Rutka, W.C.W. Chan. Nanomedicine. The New England Journal of Medicine,, 2010, 363: 2434−2443. https://doi.org/10.1056/NEJMra0912273

[13]

P. Pandey, M. Dahiya. A brief review on inorganic nanoparticles. Journal of Critical Reviews, 2016, 3: 18−26.

[14]

S. Zwyea, A.A. Mohsin, M.M. Radhi. Anti-oxidative effect of sulforaphane compound in blood medium using cyclic voltammetry. EurAsian Journal of Biosciences, 2020, 14: 6507−6512.

[15]

Z.N. Kareem, M.M. Radhi, A.A. Moosa. Cyclic voltammetric studies of micro and nano paracetamol using glassy carbon electrode modified with multi-walled carbon nanotube and graphene. Materials Science and Engineering, 2021, 1105: 012054. https://doi.org/10.1088/1757-899X/1105/1/012054

[16]

A.S. Jassim, M.M. Radhi, Z.O. Ali. Study zinc oxide nanoparticles solution as an alternative of iodine contrast medium of CT-scan imaging of the heart, kidney, and liver. Annals of the Romanian Society for Cell Biology, 2021, 25: 8793−8803.

[17]

H.K. Abd, M.M. Radhi. The use of manganese nano-molecular solution as alternative contrast media in CT-scan imaging. Annals of the Romanian Society for Cell Biology, 2021, 25: 7650−7663.

[18]

Z.O. Ali, M.M. Radhi, M.R. Jobayr. Electrochemical oxidation-reduction peaks induced by iron ions (Fe), pH and ascorbic acid (AA) in rabbit plasma assessed by cyclic voltammetry. Online Journal of Veterinary Research, 2019, 23: 829−835.

[19]

M. Fadil, M.M. Radhi, B.F. Hussein. Effect of gold on serum redox status in male and female rabbits determined by cyclic voltammetry. Online Journal of Veterinary Research, 2020, 24: 99−106.

[20]

M.P. Nikolova, M.S. Chavali. Metal oxide nanoparticles as biomedical materials. Biomimetics, 2020, 5(2): E27. https://doi.org/10.3390/biomimetics5020027

[21]

M.M. Radhi, F.K.M. Alosfur, N.J. Ridha. Voltammetric characterization of grafted polymer modified with ZnO nanoparticles on glassy carbon electrode. Russian Journal of Electrochemistry, 2018, 54: 27−32. https://doi.org/10.1134/S1023193518010068

[22]

M.M. Radhi, A.A. Obaid, L.F. Al-baram. Electrochemical study of the stevia as an alternative to the sugar in blood medium using nano-sensor by cyclic voltammetry. Biomedicine and Chemical Sciences, 2023, 2: 44−47. https://doi.org/10.48112/bcs.v2i1.339

Nano Biomedicine and Engineering
Pages 21-27
Cite this article:
Younis MAH, Radhi MM, Al-Mulla EAJ. The Effect of Aluminum Nanoparticles on Vaccine-dosed Rabbits Investigated Using Cyclic Voltammetry. Nano Biomedicine and Engineering, 2023, 15(1): 21-27. https://doi.org/10.26599/NBE.2023.9290004

1550

Views

163

Downloads

0

Crossref

0

Scopus

Altmetrics

Received: 19 November 2022
Revised: 29 December 2022
Accepted: 06 February 2023
Published: 26 April 2023
© The Author(s) 2023.

This is an open-access article distributed under  the  terms  of  the  Creative  Commons  Attribution  4.0 International  License (CC BY) (http://creativecommons.org/licenses/by/4.0/), which  permits  unrestricted  use,  distribution,  and reproduction in any medium, provided the original author and source are credited.

Return