AI Chat Paper
Note: Please note that the following content is generated by AMiner AI. SciOpen does not take any responsibility related to this content.
{{lang === 'zh_CN' ? '文章概述' : 'Summary'}}
{{lang === 'en_US' ? '中' : 'Eng'}}
Chat more with AI
Powered by AMiner. Clicking this button will take you away from SciOpen.
Home Nano Biomedicine and Engineering Article
PDF (14.5 MB)
Cite
EndNote(RIS) BibTeX
Collect
Submit Manuscript AI Chat Paper
Show Outline
Outline
Show full outline
Hide outline
Outline
Show full outline
Hide outline
Research Article | Open Access

Enhancing Osteoblast Response and Biointegration in vivo: Grown Zirconium Oxide Nanotube Bundles on Zirconium Surgical Screw

Department of Physics, College of Science, Mustansiriyah University, Baghdad, Iraq
Show Author Information

Abstract

In this paper, the surface of zirconium implant was improved by growing zirconium oxide nanotubes using a simple chemical method to increase the surface porosity and thus increase the effectiveness of bone fusion. Histopathological examinations showed the filling of the bone lakes at the implant site with live bone cells and the penetration of Haversian canals into the blood vessels. EDXS profile confirmed the signal characteristic of zirconium and oxygen. EDXS profile is another evidence of pure ZrO2 nanotubes formation. EDXS presents peaks between 0.525 and 2.044 kV, which indicate the presence of ZrO2 nanotubes. SEM result showed that homogeneous nanotubes are less in diameter with increasing concentration of glycerine.

Keywords

ZrO2 nanotube bundlesBone regenerationZr surgical screwBiointegration

References

[1]

C.L. Gregson, M.A. Paggiosi, N. Crabtree, et al., Analysis of body composition in individuals with high bone mass reveals a marked increase in fat mass in women but not men. J. Clin. Endocrinol. Metab. 2013, 98: 818-828.
Crossref Google Scholar
[2]
D. Farlay, G. Boivin, mineral quality. Osteoporosis. In Tech, 2012: 3-32.
Crossref
[3]

E. Donnelly, D.S. Meredith, J.T. Nguyen, et al., Bone tissue composition varies across anatomic sites in the proximal femur and the iliac crest. J. Orthop. Res., 2012, 30: 700-706.
Crossref Google Scholar
[4]

E.T. Everett, Fluoride's effects on the formation of teeth and bones and the influence of genetics. J. Dent. Res., 2011, 90: 552-560.
Crossref Google Scholar
[5]

J.R. Caeiro, P. González, and D. Guede, Biomechanics and bone (& Ⅱ): Trials in different hierarchical levels of bone and alternative tools for the determination of bone strength. Rev. Osteoporos. y Metab. Miner., 2013, 5: 99-108.
Crossref Google Scholar
[6]

M.J. Bojrab, D.R. Waldron, and J.P. Toombs, Current techniques in small animal surgery, 5th edition. CRC Press, Taylor and Francis Group, 2014: 1183.
Crossref
[7]

D. Fang, J. Yu, Z. Luo, et al., Fabrication parameter-dependent morphologies of self-organized ZrO2 nanotubes during anodization. J Solid State Electrochem. 2012, 16: 1219-1228.
Crossref Google Scholar
[8]
D. Fang, Z. Luo, S. Liu, et al., Photoluminescence properties and photocatalytic activities of zirconia nanotube arrays fabricated by anodization", Opt Mater 2013; 35: 1461-1466.
Crossref
[9]

C.R. Babu, N.R.M. Reddy, and K. Reddy, Synthesis and characterization of high dielectric nano zirconium oxide. Ceramics International, 2015, 41: 10675-10679.
Crossref Google Scholar
[10]

S.R. Mokhtaruddin, A.B. Mohamad, K.S. Loh, et al., Thermal properties and conductivity of Nafion-zirconia composite membrane. Malaysian Journal of Analytical Sciences, 2016, 20: 670-677.
Crossref Google Scholar
[11]

R. Sigwadi, S. Dhlamini, T. Mokrani, et al., Effect of synthesis temperature on particles size and morphology of zirconium oxide nanoparticle. Journal of Nano Research, 2017, 50: 18-31.
Crossref Google Scholar
[12]

Y. Lin, L. Zheng, L. Fan, et al., The epigenetic regulation in tooth development and regeneration. Curr. Stem Cell Res. Ther., 2018, 13.
Crossref Google Scholar
[13]

C. Gautam, J. Joyner, A. Gautam, et al., Zirconia based dental ceramics: Structure, mechanical properties, biocompatibility and applications. Dalton T., 2016, 45: 1010-1039.
Crossref Google Scholar
[14]

K. Balagangadharan, C.S. Viji, B. Arumugam, et al., Chitosan/nanohydroxyapatite/nano-zirconium dioxide scaffolds with miR-590-5p for bone regeneration. Int. J. Biol. Macromol., 2018, 111: 953-958.
Crossref Google Scholar
[15]

M.M. Gad, A. Rahoma, A.M. Al-Thobity, et al., Influence of incorporation of ZrO2 nanoparticles on the repair strength of polymethyl methacrylate denture bases. Int. J. Nanomed., 2016, 11: 5633-5643.
Crossref Google Scholar
[16]

C.I. Ossai, N. Raghavan, Nanostructure and nanomaterial characterization, growth mechanisms, and applications. Nanotechnol. Rev., 2017, 7.
Crossref Google Scholar
[17]

M. H. M. Daud, Y. Hsu Zenn, J.Q. Zaman, et al., Evaluation of shear bond strength of a novel nano-zirconia and veneering ceramics. Ceram. Int., 2017, 43: 1272-1277.
Crossref Google Scholar
[18]

P. Song, C. Hu, X. Pei, et al., Dual modulation of crystallinity and macro-/microstructures of 3D printed porous titanium implants to enhance stability and osseointegration. J. Mater. Chem. B, 2019, 7: 2865-2877.
Crossref Google Scholar
[19]

Z. Huang, Z. Wang, C. Li, et al., Application of plasma sprayed zirconia coating in dental implant: Study in implant. J. Oral Implantol., 2018, 44: 17-124.
Crossref Google Scholar
[20]

N. Goonoo, A. Bhaw-Luximon, N. Goonoo, et al., Analyzing polymeric nano fibrous scaffold performances in diabetic animal models for translational chronic wound healing research. Nanotechnol. Rev., 2017, 6.
Crossref Google Scholar
[21]

B. Gaihre, A.C. Jayasuriya, Comparative investigation of porous nano-hydroxyapaptite/chitosan, nano-zirconia/chitosan and novel nano-calcium zirconate/chitosan composite scaffolds for their potential applications in bone regeneration. Mater. Sci. Eng. C-Mater., 2018, 91: 330-339.
Crossref Google Scholar
[22]

E.S. A.V. Costa, J.A. Teixeira, C.C.B.O. Mota, et al., In vitro morphological, optical and microbiological evaluation of nanosilver fluoride in the remineralization of deciduous teeth enamel. Nanotechnol Rev., 2018, 7: 509-520.
Crossref Google Scholar
[23]

M. Gad, A.S. Arrejaie, M.S. Abdel-Halim, et al., The reinforcement effect of nano-zirconia on the transverse strength of repaired acrylic denture base. Int. J. Dent., 2016: 7094056.
Crossref Google Scholar
[24]

M.D. Jerez-Masaquiza, L. Fernández, G. González, et al., Electrochemical sensor based on prussian blue electrochemically deposited at ZrO2 doped carbon nanotubes glassy carbon modified electrode. Nanomaterials, 2020, 10(7): 1328.
Crossref Google Scholar
[25]

A. Meng, L. Lin, X. Yuan, et al., Ag/ZrO2/MWCNT nanocomposite as non-platinum electrocatalysts for enhanced oxygen reduction reaction. ChemCatChem, 2019, 11(12): 2900-2908.
Crossref Google Scholar
[26]

R.B. Anjaneyulu, B.S. Mohan, G.P. Naidu, et al., ZrO2/Fe2O3/RGO nanocomposite: Good photocatalyst for dyes degradation. Physica E: Low-dimensional Systems and Nanostructures, 2019, 108: 105-111.
Crossref Google Scholar
[27]

I. Zhao, L. Li, J. Li, et al., Electrical transport properties of self-organized ZrO2 nanotube. ECS Journal of Solid State Science and Technology, 2019, 8(4): 258: 261.
Crossref Google Scholar
[28]

S.S. Ghahfarokhi, R.S. Mamoory, and A.G. Kalashami, Inverse precipitation synthesis of ZrO2 nanopowder and in-situ coating on MWCNTs. Ceramics International, 2018, 44(12): 13556-13564.
Crossref Google Scholar
[29]

M.A.M. Hassan, D.K. Kafi, Porous scaffold implantation for bone fractures healing. 2020 IOP Conf. Ser.: Mater. Sci. Eng., 2020, 928: 072085.
Crossref Google Scholar
[30]

M.A.M. Hassan, A.M. Abbas, and M.J.M. Ali, Construction of scaffold from MgO nanoparticle: Bone fracture healing. 2020 IOP Conf. Ser.: Mater. Sci. Eng., 2020, 928: 072133.
Crossref Google Scholar
Nano Biomedicine and Engineering
Volume 13 Issue 3,
September 2021
Pages 213-224
DOI: 10.5101/nbe.v13i3.p213-224
Cite this article:
Mohammed AH, Hassan MAM. Enhancing Osteoblast Response and Biointegration in vivo: Grown Zirconium Oxide Nanotube Bundles on Zirconium Surgical Screw. Nano Biomedicine and Engineering, 2021, 13(3): 213-224. https://doi.org/10.5101/nbe.v13i3.p213-224

662

Views

35

Downloads

1

Crossref

1

Scopus

Altmetrics
Received: 04 September 2020
Accepted: 30 April 2021
Published: 19 July 2021
© Asmaa Hadi Mohammed, Marwa Abdul Muhsien Hassan.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Return