AI Chat Paper
Note: Please note that the following content is generated by AMiner AI. SciOpen does not take any responsibility related to this content.
{{lang === 'zh_CN' ? '文章概述' : 'Summary'}}
{{lang === 'en_US' ? '中' : 'Eng'}}
Chat more with AI
Powered by AMiner. Clicking this button will take you away from SciOpen.
Home Nano Biomedicine and Engineering Article
PDF (7 MB)
Cite
EndNote(RIS) BibTeX
Collect
Submit Manuscript AI Chat Paper
Show Outline
Outline
Show full outline
Hide outline
Outline
Show full outline
Hide outline
Review | Open Access

Drug Delivery Systems Based on Polymeric Blend: A Review

Khalid Haneen Abass1( ), Ashraq Mohammed Kadim2, Sara Kareem Mohammed3, Mohd Arif Agam4
Department of Physics, College of Education for Pure Sciences, University of Babylon, Iraq
Medical physics department, Hilla University College, Babylon, Iraq
Technical Institute of Karbala, Iraq
Department of Physics, Faculty of Applied Sciences and Technology, University Tun Hussein Onn Malaysia, 84600 Pagoh, Johor, Malaysia
Show Author Information

Abstract

Non-idealistic pharmaceutical, pharmacokinetic and therapeutic-characteristic predominately combines to decrease the effectiveness of certain composites. For the vectoring of such compounds to target areas, and liposomes and nanoparticles carrier technology provides an interesting and intelligent approach to drug delivery. It provides drug delivery by conjugating the drug to a transporter particle-like, microscopes, liposomes, nanoparticles, et cetera. Due to their small size and other effective properties, microspheres are an important portion of a drug-particle delivery system. The release systems are very important and can compare with the fabrication methods, this when the drug delivery become inside the body. This review highlights different types of drug delivery and drug delivery methods this article also focuses on different types of microspheres such as radioactive float microspheres biological adhesive microspheres, polymeric microbes, microspheres, and magnetic microspheres.

Keywords

MicrospheresControlled releaseTypes of drug deliveryTarget drug delivery

References

[1]

S. Mitra, U. Gaur, P.C. Ghosh, et al., Tumour Targeted Delivery of Encapsulated Dextran–Doxorubicin Conjugate Using Chitosan Nanoparticles as Carrier. Journal of Controlled Release, 2001, 74(1-3): 317-323.
Crossref Google Scholar
[2]

Y.W. Chein, Oral Drug Delivery and Delivery Systems. Novel Drug Delivery Systems, 1992, 50: 139-177.
Crossref Google Scholar
[3]

A. Mitra, B. Dey, Chitosan Microspheres in Novel Drug Deliver Systems. Indian Journal of Pharmaceutical Sciences, 2011, 73(4): 355.
Google Scholar
[4]

F. Sharifi, A.C. Sooriyarachchi, H. Altural, et al., Fiber Based Approaches as Medicine Delivery Systems. ACS Biomaterials Science & Engineering, 2016, 2(9): 1411-1431.
Crossref Google Scholar
[5]

R. Langer, Drug Delivery and Targeting. Nature, 1998, 392(6679 Suppl): 5-10.
Google Scholar
[6]

A.N. Al-Jamal, Q.M. Hadi, F.J. Hamood, et al., Particle Size Effect of Sn on Structure and Optical Properties of PVA-PEG Blend. Proceedings - International Conference on Developments in eSystems Engineering, DeSE, 2019: 736-740.
Crossref Google Scholar
[7]

S.M. Al Asadi, F.J. Hamood, K.H. Abass, et al., The Effect of MgO Nanoparticles on Structure and Optical Properties of PVA-PAAm Blend. Research Journal of Pharmacy and Technology, 2019, 12(6): 2768-2771.
Crossref Google Scholar
[8]

K.S. Sharba, A.S. Alkelaby, M.D. Sakhil, et al., Enhancement of Urbach Energy and Dispersion Parameters of Polyvinyl Alcohol with Kaolin Additive. NeuroQuantology, 2020, 18(3): 66-73.
Crossref Google Scholar
[9]

H. Maeda, J. Fang, T. Inutsuka, et al., Vascular Permeability Enhancement in Solid Tumor: Various Factors, Mechanisms Involved and its Implications. International Immunopharmacology, 2003, 3(3): 319-328.
Crossref Google Scholar
[10]

I. Mishra, Dendrimer: a Novel Drug Delivery System. Journal of Drug Delivery and Therapeutics, 2011, 1(2).
Crossref Google Scholar
[11]

A.D. Bangham, M.M. Standish, J.C. Watkins, Diffusion of Univalent Ions Across the lamellae of Swollen Phospholipids. Journal of Molecular Biology, 1965, 13(1): 238-252.
Crossref Google Scholar
[12]

T.M. Allen, P.R. Cullis, Liposomal Drug Delivery Systems: from Concept to Clinical Applications. Advanced drug delivery reviews, 2013, 65(1): 36-48.
Crossref Google Scholar
[13]
G. Gregoriadis, Y. Perrie, Liposomes, Encycl Life Sci, 2010: 1-8.
Crossref
[14]

L. Sercombe, T. Veerati, F. Moheimani, et al., Advances and Challenges of Liposome Assisted Drug Delivery. Frontiers in Pharmacology, 2015, 6: 286.
Crossref Google Scholar
[15]

E. Blanco, C.W. Kessinger, B.D. Sumer, et al., Multifunctional Micellar Nanomedicine for Cancer Therapy. Experimental biology and medicine, 2009, 234(2): 123-131.
Crossref Google Scholar
[16]

S. Vijayaraghavalu, D. Raghavan, V. Labhasetwar, Nanoparticles for Delivery of Chemotherapeutic Agents to Tumors. Current opinion in investigational drugs (London, England: 2000), (2007), 8(6): 477-484.
Google Scholar
[17]

A. Senthil, V.B. Narayanaswamy, I. Ajit, et al., Mucoadhesive Microspheres. International Journal of Research in Ayurveda and Pharmacy, 2011, 2(1): 55-59.
Google Scholar
[18]

N.R. Kadam, V. Suvarna, Microsphere: a Brief Review. Asian Journal of Biomedical and Pharmaceutical Sciences, 2015, 5(47): 13.
Crossref Google Scholar
[19]

S. B. Gholap, S.K. Banarjee, D.D. Gaikwad, et al., Hollow microsphere: A Review. International Journal of Pharmaceutical Sciences Review and Research, 2010, 1(1): 74-79.
Google Scholar
[20]

K.H. Ramteke, V.B. Jadhav, S.N. Dhole, Microspheres: as Carrieres used for Novel Drug Delivery System. Iosrphr, 2012, 2(4): 44-48.
Crossref Google Scholar
[21]

K. Sahil, M. Akanksha, S. Premjeet, et al., Microsphere: A Review. Int. J. Res. Pharm. Chem, 2011, 1(4): 1184-1198.
Google Scholar
[22]

J. Kunisawa, A. Okudaira, Y. Tsutusmi, et al., Characterization of Mucoadhesive Microspheres for the Induction of Mucosal and Systemic Immune Responses. Vaccine, 2000, 19(4-5): 589-594.
Crossref Google Scholar
[23]

K.P.R. Chowdary, Y.S. Rao, Mucoadhesive Microspheres for Controlled Drug Delivery. Biological and Pharmaceutical Bulletin, 2004, 27(11): 1717-1724.
Crossref Google Scholar
[24]

V. Belgamwar, V. Shah, S.J. Surana, Formulation and Evaluation of Oral Mucoadhesive Multiparticulate System Containing Metoprolol Tartarate: an in Vitro-ex Vivo Characterization. Current Drug Delivery, 2009, 6(1): 113-121.
Crossref Google Scholar
[25]

N. Özdemir, S. Ordu, Y. Özkan, Studies of Floating Dosage forms of Furosemide: in Vitro and in Vivo Evaluations of Bilayer Tablet Formulations. Drug Development and Industrial Pharmacy, 2000, 26(8): 857-866.
Crossref Google Scholar
[26]

K.M.Z. Hossain, U. Patel, I. Ahmed Development of Microspheres for Biomedical Applications: a Review. Progress in biomaterials, 2015, 4(1): 1-19.
Crossref Google Scholar
[27]

C.M. Lehr, J.A. Bouwstra, W. Kok, Bioadhesion by Means of Specific Binding of Tomato Lectin. Pharmaceutical Research, 1992, 9(4): 547-553.
Crossref Google Scholar
[28]

S. Wright, L. Huang, Antibody-Directed Liposomes as Drug-Delivery Vehicles. Advanced Drug Delivery Reviews, 1989, 3(3): 343-389.
Crossref Google Scholar
[29]
P.R. Radhika, M. Luqman, C.H. Borkhataria, Preparation and Evaluation of Delayed Release Aceclofenac Microspheres. Asian Journal of Pharmaceutics (AJP): Free full text articles from Asian J Pharm, 2014, 2(4).
Crossref
[30]

P.N. Bhangale, H.S. Mahajan, R.D. Wagh, Formulation and Development of Sustained Release Microspheres of Metformin Hydrochloride. Research Journal of Pharmacy and Technology, 2010, 3(1): 267-271.
Google Scholar
[31]

S.P. Senthil, K.L. Senthilkumar, Preparation and In-Vitro Evaluation of Abacavir Sulphate Loaded Microspheres Cross-Linked by Different Concentrations of Glutaraldehyde. Research Journal of Pharmacy and Technology 2010, 3.4: 1128-1131.
Google Scholar
[32]

M. Jamini, S.A. Rawat, Review on Microsphere. Res. J. Pharm. Boil. Chem. Sci, 2013, 4(1): 1223-1233.
Google Scholar
[33]

N.R. Patel, D.A. Patel, P.D. Bharadia, et al., Microsphere as a Novel Drug Delivery. International Journal of Pharmacy Life Sciences, 2011, 2(8).
Google Scholar
[34]

S.H. Kareem, A.M. Naji, Z.J. Taqi, et al., Polyvinylpyrrolidone Loaded-MnZnFe2O4 Magnetic Nanocomposites Induce Apoptosis in Cancer Cells Through Mitochondrial Damage and P53 Pathway. Journal of Inorganic and Organometallic Polymers and Materials, 2020, 30(12): 5009-5023.
Crossref Google Scholar
[35]

K.H. Abass, A.H. Hamed, Reduction of Energy Gap in ZrO2 Nanoparticles on Structural and Optical Properties of Casted PVA–PAAm Blend. Journal of Green Engineering, 2020, 10(7): 4166-4176.
Google Scholar
[36]

J.K. Patra, G. Das, L.F. Fraceto, et al., Nano based drug delivery systems: recent developments and future prospects. Journal of Nanobiotechnology, 2018, 16(1): 71.
Crossref Google Scholar
[37]

G. Tiwari, R. Tiwari, B. Sriwastawa, et al., Drug Delivery Systems: An Apdated Review. International Journal of Pharmaceutical Investigation, 2012, 2(1): 2.
Crossref Google Scholar
[38]

A.J. Guastella, I.B. Hickie, M.M. McGuinness, et al., Recommendations for the Standardisation of Oxytocin Nasal Administration and Guidelines for its Reporting in Human Research. Psychoneuroendocrinology, 2013, 38(5): 612-625.
Crossref Google Scholar
[39]

C.V. Pardeshi, V.S. Belgamwar, Direct Nose to Brain Drug Delivery Via Integrated Nerve Pathways Bypassing the Blood–Brain Barrier: an Excellent Platform for Brain Targeting. Expert Opinion on Drug Delivery, 2013, 10(7): 957-972.
Crossref Google Scholar
[40]
A. Boxi, Preparation and Characterization of Gelatin Stavudine Conjugated Liposomal Nanoparticles For Better Delivery in Case of Hiv. Doctoral Dissertation, National Institute Of Technology Rourkela, 2015.
[41]
S. Maiti, K.K. Sen, (Eds. ). Bio-Targets and Drug Delivery Approaches. CRC Press, 2016.
Crossref
[42]

G. Tiwari, R. Tiwari, B. Sriwastawa, et al., Drug Delivery Systems: An Updated Review. International Journal of Pharmaceutical Investigation, 2012, 2(1): 2.
Crossref Google Scholar
[43]

S. Hossen, M.K. Hossain, M.K. Basher, Smart Nanocarrier-Based Drug Delivery Systems for Cancer Therapy and Toxicity Studies: A Review. Journal of Advanced Research, 2019, 15: 1-18.
Crossref Google Scholar
[44]

G. Paradossi, F. Cavalieri, E. Chiessi, et al., Poly(Vinyl Alcohol) as Versatile Biomaterial for Potential Biomedical Applications. Journal of Materials Science: Materials in Medicine, 2003, 14(8): 687-691.
Crossref Google Scholar
[45]

P. Khare, S.K. Jain, Influence of Rheology of Dispersion Media in the Preparation of Polymeric Microspheres Through Emulsification Method. AAPS Pharm Sci Tech, 2009, 10(4): 1295-1300
Crossref Google Scholar
[46]

M.N. Abdorreza, M. Robal, L.H. Cheng, et al., Physicochemical, Thermal, and Rheological Properties of Acid-Hydrolyzed Sago (Metroxylon Sagu) Starch. LWT-Food Science and Technology, 2012, 46(1): 135-141.
Crossref Google Scholar
[47]

S. Geng, B. Yang, G. Wang, et al., Two Cholesterol Derivative-Based PEGylated Liposomes as Drug Delivery system, Study on Pharmacokinetics and Drug Delivery to Retina. Nanotechnology, 2014, 25(27): 275103.
Crossref Google Scholar
[48]

H. Chattopadhyay, A.K. De, S. Datta, Novel Starch-PVA Polymer for Microparticle Preparation and Optimization Using Factorial Design Study. International Scholarly Research Notices, 2015: 2015.
Crossref Google Scholar
[49]

A. Puiggalí-Jou, A. Cejudo, L.J. del Valle, et al., Smart Drug Delivery from Electrospun Fibers through electroresponsive polymeric nanoparticles. ACS Applied Bio Materials, (2018), 1(5): 1594-1605.
Crossref Google Scholar
[50]

G.R. Mahdavinia, M. Soleymani, H. Etemadi, et al., Model Protein BSA Adsorption Onto Novel Magnetic Chitosan/PVA/Laponite RD Hydrogel Nanocomposite Beads. International journal of Biological Macromolecules, 2018, 107: 719-729.
Crossref Google Scholar
[51]

A.S. Chauhan, Dendrimers for drug delivery. Molecules, 2018, 23(4): 938.
Crossref Google Scholar
[52]

A. Luraghi, F. Peri, L. Moroni, Electrospinning for drug delivery applications: A review. Journal of Controlled release, 2021, 334: 463-484.
Crossref Google Scholar
[53]

N. Hadi, A. Braihi, S.K. Mohammed, Effect of Flow Behavior on the Production of PVA/Dextrin Microspheres. International Journal of Engineering and Technology, 2019, 8(1.5): 214-221.
Google Scholar
[54]

M. Smola, T. Vandamme, A. Sokolowski, Nanocarriers as Pulmonary Drug Delivery Systems to Treat and to Diagnose Respiratory and Non-Respiratory Diseases. International Journal of Nanomedicine, 2008, 3(1): 1.
Crossref Google Scholar
[55]

T.J. Kean, P. Lin, A. I. Caplan, et al., MSCs: Delivery Routes and Engraftment, Cell-Targeting Strategies, and Immune Modulation. Stem Cells International, 2013: 2013.
Crossref Google Scholar
[56]

C.J. Cheng, G.T. Tietjen, J.K. Saucier-Sawyer, et al., A Holistic Approach to Targeting Disease with Polymeric Nanoparticles. Nature Reviews Drug Discovery, 2015, 14(4): 239-247.
Crossref Google Scholar
[57]

M.M. Zacchè, S. Srikrishna, L. Cardozo, Novel Targeted Bladder Drug-Delivery Systems: A Review. Research and Reports in Urology, 2015, 7: 169.
Crossref Google Scholar
[58]

K.R. Chowdary, N.K. Rao, K. Malathi, Ethyl Sellulose Microspheres of Glipizide: Characterization, in Vitro and in Vivo Evaluation. Indian Journal of Pharmaceutical Sciences, 2004, 66(4): 412.
Google Scholar
[59]

S. Surini, V. Anggriani, E. Anwar, Study of Mucoadhesive Microspheres Based on Pregelatinized. J Med Sci, 2009, 9: 249-56.
Crossref Google Scholar
[60]

S. Fischer, C. Foreg, P.H. Merkle, et al., Chitosan Coated Plga-Microspheres-A Modular System for Targetting Drug Delivery. European Cells and Materials, 2004, 7(1).
Google Scholar
[61]
O.G. Bhusnure, C.A. Shinde, S.B. Gholve, et al., Design, Evaluation and Aseptic Refiner Techniques for Microsphere Formation, (2015).
[62]

J.A. Yabagi, I.M. Kimpa, M.N. Muhammad, et al., Structural Transformation of Polystyrene Nanosphere Produce Positive and Negative Resists by Controlled Laser Exposure. Advanced Science Letters, 2017, 23(7): 6613-6617. ‏
Crossref Google Scholar
[63]

P.J. Wibawa, M.A. Agam, H. Nur, et al., Changes in Physical Properties and Molecular Structure of Polystyrene Nanospheres Exposed with Solar Flux. In AIP Conference Proceedings, American Institute of Physics, 2011, 1341(1): 54-61.
Crossref Google Scholar
[64]

H. Farzaneh, M.E. Nik, M. Mashreghi, et al., A Study on the Role of Cholesterol and Phosphatidylcholine in Various Features of Liposomal Doxorubicin: From Liposomal Preparation to Therapy. International Journal of Pharmaceutics, 2018, 551(1-2): 300-308.
Crossref Google Scholar
[65]
A.M. Kadim, A. Dheyaa, A. Jawad, et al., Formation of PVA-PMMA-PAAm Blend with Various content of Dextrin for Drug Delivery Application. Materialstoday: Proceedings, July, 2021.
[66]

R. Rathinamoorthy, M. Sumothi, Innovative Application of Nano Fiber. Textile Asia, 2009, 1: 24-27.
Google Scholar
[67]
A.A. Hamidi, Synthesis Of Pamam Dendrimer As A New Carrier In Cancer Drug Delivery, 2016.
[68]

C. Jiang, L. Kuang, M.P. Merkel, et al., Biodegradable Polymeric Microsphere-Based Drug Delivery for Inductive Browning of Fat. Frontiers in Endocrinology, 2015, 6: 169.
Crossref Google Scholar
[69]

K.H. Ramteke, V.B. Jadhav, S.N. Dhole, Microspheres: as Carrieres Used for Novel Drug Delivery System. IOSRPHR, 2012, 2(4): 44-48.
Crossref Google Scholar
[70]
M. (Ed. ). Mishra, Handbook of Encapsulation and Controlled Release. CRC Press, 2015.
Crossref
[71]
W. Dina, The Study of Actors Affecting the Preparation of Carbon Microspheres by Hydrothermal method, (2016).
[72]

X. Yang, L. Chen, B. Han, et al., Preparation of Magnetite and Tumor Dual-Targeting Hollow Polymer Microspheres with PH- Sensitivity for Anticancer Drug-Carriers. Polymer, 2010, 51(12): 2533-2539.
Crossref Google Scholar
[73]

H. Tian, Z. Tang, X. Zhuang, et al., Biodegradable synthetic polymers: preparation, functionalization and biomedical application. Progress in Polymer Science, 2012, 37(2): 237-280.
Crossref Google Scholar
[74]
https://www.grandviewresearch.com/industryanalysis/microspheres-industry, (accessed) 11/10/2018.
[75]

A. Kumar, S. Jha, R. Rawal, et al., Mucoadhesive Microspheres for Novel Drug Delivery System: A Review. Am. J. PharmTech Res, 2013, 3: 196-213.
Google Scholar
[76]

A.V. Thummar, C.R. Kyada, R. Kalyanvat, et al., A Review on Mucoadhesive Microspheres as a Novel Drug Delivery System. International Journal for Pharmaceutical Research Scholars, 2013, 2(2): 188-200.
Google Scholar
[77]

S. Mukherjee, P. Bandyopadhyay, Magnetic Microspheres: A Latest Approach in Novel Drug Delivery System. J Pharm Sci Innovation, 2012, 26: 21-25.
Google Scholar
[78]

D. Batra, S. Kakar, R. Singh, et al., Magnetic Microspheres as A Targeted Drug Delivery System: An Overview. Journal of Drug Delivery Research, 2012, 1(3): 10-17.
Google Scholar
[79]

M.S. Roslan, K.T. Chaudhary, N. Doylend, et al., Growth of Wall-Controlled MWCNTs by Magnetic Field Assisted arc Discharge Plasma. Journal of Saudi Chemical Society, 2019, 23(2), 171-181.
Crossref Google Scholar
[80]

A.V. Mayavanshi, S.S. Gajjar, Floating Drug Delivery Systems to Increase Gastric Retention of Drugs: A Review. Research Journal of Pharmacy and Technology, 2008, 1(4): 345-348.
Google Scholar
[81]

V. Rastogi, S.S. Shukla, R. Singh, et al., Microspheres: A Promising Drug Carrier. Journal of Drug Delivery and Therapeutics, 2016, 6(3): 18-26.
Crossref Google Scholar
[82]

K.H. Ramteke, V.B. Jadhav, S.N. Dhole, Microspheres: As Carrieres used for Novel Drug Delivery System. Iosrphr, 2012, 2(4): 44-48.
Crossref Google Scholar
[83]

N.A. Gujarathi, B.R. Rane, J.K. Patel, PH Sensitive Polyelectrolyte Complex of O-Carboxymethyl Chitosan and Poly (Acrylic Acid) Cross-Linked with Calcium for Sustained Delivery of Acid Susceptible Drugs. International Journal of Pharmaceutics, 2012, 436(1-2): 418-425.
Crossref Google Scholar
[84]

T.M. Allen, P.R. Cullis, Drug Delivery Systems: Entering the Mainstream. Science, 2004, 303(5665): 1818-1822.
Crossref Google Scholar
[85]

J.M. Frechet, Dendrimers and Other Dendritic Macromolecules: From Building Blocks to Functional Assemblies in Nanoscience and Nanotechnology. Journal of Polymer Science Part A: Polymer Chemistry, 2003, 41(23): 3713-3725.
Crossref Google Scholar
[86]

F.M. Muggia, J.D. Hainsworth, S. Jeffers, et al., Phase Ⅱ study of liposomal doxorubicin in refractory ovarian cancer: antitumor activity and toxicity modification by liposomal encapsulation. Journal of Clinical Oncology, 1997, 15(3): 987-993.
Crossref Google Scholar
[87]

J. Panyam, & amp; Labhasetwar, V. Biodegradable Nanoparticles for Drug and Gene Delivery to Cells and Tissue. Advanced Drug Delivery Reviews, 2003, 55(3): 329-347.
Crossref Google Scholar
[88]

H. Otsuka, Y. Nagasaki, K. Kataoka, PEGylated Nanoparticles for Biological and Pharmaceutical Applications. Advanced Drug Delivery Reviews, 2003, 55(3): 403-419.
Crossref Google Scholar
[89]

I. Imaz, J. Hernando, D. Ruiz-Molina, et al., Metal–Organic Spheres as Functional Systems for Guest Encapsulation. Angewandte Chemie International Edition, 2009, 48(13): 2325-2329.
Crossref Google Scholar
[90]

M. Oh, C.A. Mirkin, Chemically Tailorable Colloidal Particles from Infinite Coordination Polymers. Nature, 2005, 438(7068): 651-654.
Crossref Google Scholar
[91]

X. Sun, S. Dong, E. Wang, Coordination-induced Formation of Submicrometer-Scale, Monodisperse, Spherical Colloids of Organic-Inorganic Hybrid Materials at Room Temperature. Journal of the American Chemical Society, 2005, 127(38): 13102-13103.
Crossref Google Scholar
[92]

P. Horcajada, C. Serre, M. Vallet-Regí, et al., Metal-Organic Frameworks as Efficient Materials for Drug Delivery. Angewandte Chemie, 2006, 118(36): 6120-6124.
Crossref Google Scholar
[93]

P. Horcajada, C. Serre, G. Maurin, et al., Flexible Porous Metal-Organic Frameworks for A Controlled Drug Delivery. Journal of the American Chemical Society, 2008, 130(21): 6774-6780.
Crossref Google Scholar
[94]

W.J. Rieter, K.M. Pott, K.M. Taylor, et al., Nanoscale Coordination Polymers for Platinum-Based Anticancer Drug Delivery. Journal of the American Chemical Society, 2008, 130(35): 11584-11585.
Crossref Google Scholar
[95]

P. Horcajada, T. Chalati, C. Serre, et al., Porous Metal-Organic-Framework Nanoscale Carriers as a Potential Platform for Drug Delivery and Imaging. Nature Materials, 2010, 9(2): 172-178.
Crossref Google Scholar
[96]

I. Imaz, M. Rubio-Martínez, L. García-Fernández, et al., Coordination Polymer Particles as Potential Drug Delivery Systems. Chemical Communications, 2010, 46(26): 4737-4739.
Crossref Google Scholar
[97]

T. Wang, S. Yang, L. Wang, et al., Use of Poly (Amidoamine) Dendrimer for Dentinal Tubule Occlusion: A Preliminary Study. PLoS One, 2015, 10(4): e0124735.
Crossref Google Scholar
Nano Biomedicine and Engineering
Volume 13 Issue 4,
December 2021
Pages 414-424
DOI: 10.5101/nbe.v13i4.p414-424
Cite this article:
Haneen Abass K, Mohammed Kadim A, Kareem Mohammed S, et al. Drug Delivery Systems Based on Polymeric Blend: A Review. Nano Biomedicine and Engineering, 2021, 13(4): 414-424. https://doi.org/10.5101/nbe.v13i4.p414-424

888

Views

93

Downloads

4

Crossref

5

Scopus

Altmetrics
Received: 14 June 2021
Accepted: 18 October 2021
Published: 09 December 2021
© Khalid Haneen Abass, Ashraq Mohammed Kadim, Sara Kareem Mohammed, and Mohd Arif Agam.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Return