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Review | Open Access

SARS-CoV-2: Literature Review Focusing on Structure, Diagnosis and Vaccine Development

Mohammed Hamzah Abdulkadhim Al-Saadi1, Wisam Hindawi Hoidy2( )
University of Al Qadisiyah, Chemistry Alsadi, Mohamed, Iraq
Department of Chemistry, College of Education, University of Al-Qadisiyah, Al-Qadisiyah City, Iraq
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Abstract

SARS-CoV-2 is a highly pathogenic novel ongoing-pandemic virus. It causes COVID-19. Little is known about SARS-CoV-2 biology, countermeasure, and its origin. SARS-CoV-2 is characterized by high infectiousness and sever pathogenesis. COVID-19 crosses the bounders of all continents in a high spreading manner. Here, several aspects regarding the origin and the molecular structure of this novel virus as well as the production of effective vaccines have been addressed. This article illustrated that SARS-CoV-2 was not being recombined inside laboratory and it has a complicated genome that led to sophisticated pathogenesis. Additionally, an important structural protein known as spike S was demonstrated by researchers as an important protein used by the virus for host cell entry as well as for vaccine development. However, the efforts for viral diagnosis and genomic demonstration as well as vaccine production are promising to tackle COVID-19. These perspectives will help in COVID-19 control. However, further investigations are urgently needed to figure out which controlling tactic is more efficient not only in the case of SARS-CoV-2 but also for future pandemics.

Keywords

COVID-19SARS-CoV-2Vaccine development

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Nano Biomedicine and Engineering
Volume 14 Issue 4,
December 2022
Pages 343-348
DOI: 10.5101/nbe.v14i4.p343-348
Cite this article:
Al-Saadi MHA, Hoidy WH. SARS-CoV-2: Literature Review Focusing on Structure, Diagnosis and Vaccine Development. Nano Biomedicine and Engineering, 2022, 14(4): 343-348. https://doi.org/10.5101/nbe.v14i4.p343-348

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Received: 26 June 2022
Revised: 02 September 2022
Accepted: 16 December 2022
Published: 31 December 2022
© Mohammed Hamzah Abdulkadhim Al-Saadi and Wisam Hindawi Hoidy.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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